Amino terminal sequence analysis of human placenta aromatase.
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Chen S, Shively JE, Nakajin S, Shinoda M, Hall PF
Amino terminal sequence analysis of human placenta aromatase.
Biochem Biophys Res Commun. 1986 Mar 28;135(3):713-9.
- PubMed ID
- 3964273 [ View in PubMed]
- Abstract
The amino acid composition and the amino-terminal amino acid sequence from position 1 to 21 of human placenta aromatase were determined. In addition, a cysteine containing peptide with a sequence homologous to those of peptides containing the cysteine residue which was suggested to provide the proximal thiolate ligand to the heme in other cytochrome p-450 isozymes, was identified. The results indicate that aromatase is a cytochrome p-450 protein, probably derived from a new cytochrome p-450 family.