| Voriconazole | A triazole compound used to treat fungal infections. |
| Telithromycin | An ketolide used to treat community acquired pneumonia of mild to moderate severity. |
| Saquinavir | An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency. |
| Darunavir | A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies. |
| Posaconazole | A triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients. |
| Telaprevir | An NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections. |
| Idelalisib | An antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). |
| Stiripentol | An anticonvulsant agent used with clobazam and valproate as an adjunct to treat refractory generalized tonic-clonic seizures in Dravet syndrome. |
| Midostaurin | An antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL). |
| Curcumin | No approved therapeutic indications. |
| Conivaptan | An antidiuretic hormone inhibitor used to raise serum sodium levels. |
| Mibefradil | For the treatment of angina and high blood pressure. |
| Efavirenz | A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV. |
| Tipranavir | A protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor. |
| Atazanavir | An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV. |
| Naloxone | An opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection. |
| Nilotinib | A kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib. |
| Danoprevir | Danoprevir has been used in trials studying the treatment of Hepatitis C, Chronic. |
| Elvitegravir | An antiretroviral agent used in combination with other antiretrovirals for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. |
| Lopinavir | An HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection. |
| Indinavir | A protease inhibitor used to treat HIV infection. |
| Delavirdine | A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection. |
| Loperamide | A long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis. |
| Ribociclib | A kinase inhibitor used to treat HR+, HER2- advanced or metastatic breast cancer. |
| Terfenadine | For the treatment of allergic rhinitis, hay fever, and allergic skin disorders. |
| Ergotamine | A alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches. |
| Econazole | A topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor. |
| Clarithromycin | A macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection. |
| Nefazodone | An antidepressant used in the treatment of depression. |
| Boceprevir | A hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy. |
| Ketoconazole | A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections. |
| Troleandomycin | For the treatment of bacterial infection. |
| Nelfinavir | A viral protease inhibitor used in the treatment of HIV infection. |
| Itraconazole | An antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis. |
| Cobicistat | A CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection. |
| Ritonavir | An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection. |
| Diltiazem | A calcium channel blocker used to treat hypertension and to manage chronic stable angina. |
| Clotrimazole | A topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis. |