Filariasis (DBCOND0009884)
Identifiers
- Synonyms
- Filariasis, unspecified / Disease due to superfamily Filarioidea (disorder) / Unspecified filariasis / Elephantiasis tropica
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Mebendazole A benzimidazole anthelmintic used to treat helminth infections.- Tubulin alpha-1A chaintarget
- Tubulin beta-4B chaintarget
- Cytochrome P450 1A1enzyme
- Cytochrome P450 3A Subfamilyenzyme
- Clinical Trials
Identifier Title Drug(s) Purpose Phase Status NCT01628497 Exhaled NO Testing in Filariasis No drug interventions Not Available Not Available completed NCT02929134 A 24 Month Study to Compare Efficacy of Doxycycline vs Placebo for Improving Filarial Lymphedema in Sri Lanka treatment 3 completed NCT02927496 A 24 Month Study, to Compare the Efficacy of Doxycycline vs. Placebo for Improving Filarial Lymphedema in Mali treatment 3 completed NCT00471666 Medical Implications of Coinfection With Malaria and Filariasis Parasites No drug interventions Not Available Not Available completed NCT03014167 Field Studies on the Feasibility of Interrupting the Transmission of Soil-transmitted Helminths (STH) treatment 3 active_not_recruiting NCT03383614 Safety, Tolerability and PK of Multiple-ascending Doses of Emodepside No drug interventions treatment 1 completed NCT03383523 Relative Bioavailability Study of Emodepside IR-tablets and Solution treatment 1 completed NCT02929121 A 24 Month Study to Compare Efficacy of Doxycycline vs Placebo for Improving Filarial Lymphedema in India treatment 3 completed NCT01547884 Effect of Filarial Infection on Immune Responses in Latent Tuberculosis No drug interventions Not Available Not Available completed NCT00001230 Host Response to Infection and Treatment in Filarial Diseases Not Available Not Available recruiting NCT04920292 PK, Safety and Tolerability of Single and Multiple Doses of Oxfendazole Tablets treatment 1 completed