Respiratory Distress Syndrome, Newborn (DBCOND0029090)

Identifiers

Synonyms
Newborn Respiratory Distress Syndrome / Respiratory distress syndrome of newborn / Respiratory distress of newborn, unspecified / Syndrome respiratory distress newborn / Respiratory distress syndrome newborn / Distress respiratory syndrome newborn / Respiratory distress syndrome in newborn / Respiratory distress syndrome in the newborn (disorder) / Respiratory distress of newborn / Neonatal respiratory distress syndrome / Respiratory distress syndrome (neonatal) / Infant respiratory distress syndrome / Surfactant deficiency syndrome neonatal

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02570217
HHHFNC (Heated Humidified High-Flow Nasal Cannula) Versus NCPAP for Respiratory Distress Syndrome of PrematurityNo drug interventionstreatmentNot Availablecompleted
NCT00599651
Randomized Controlled Trial of Surfactant Administration by Laryngeal Mask Airway (LMA)No drug interventionspreventionNot Availableterminated
NCT06446453
Echography-guided Surfactant THERapy (ESTHER) For Preterm Infants With Respiratory FailureNo drug interventionstreatmentNot Availablerecruiting
NCT06394583
LUS AT BIRTH IN INFANTS BORN BEFORE 26 WEEKSNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02835209
Positioning During SBT in NICU InfantsNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00368485
Neural Control of Non-invasive Ventilation in the PretermNo drug interventionstreatment1completed
NCT03120585
Fluid Restriction in Respiratory Distress of the NewbornNo drug interventionstreatmentNot Availablecompleted
NCT01039285
Exogenous Surfactant in Very Preterm Neonates in Prevention of Bronchopulmonary Dysplasiatreatment4completed
NCT00739115
The Use of Heliox Via Nasal CPAP to Prevent Early CPAP Failure in Premature Infants: A Feasibility StudyNo drug interventionspreventionNot Availablecompleted
NCT01173237
Efficacy Evaluation of Surfactant Administration Via Laryngeal Mask AirwayNo drug interventionstreatment4unknown_status
NCT00751959
Surfactant Application During Spontaneous Breathing With Continuous Positive Airway Pressure (CPAP) in Premature Infants < 27 WeekstreatmentNot Availablecompleted
NCT00014859
Epidemiology of Surfactant Protein-B DeficiencyNo drug interventionsNot AvailableNot Availablecompleted
NCT04406142
Surfactant Administration Via Thin Catheter Using a Specially Adapted Video Laryngoscope - the VISUAL MethodNo drug interventionstreatmentNot Availablecompleted
NCT00814099
Sedation Management in Pediatric Patients With Acute Respiratory Failure (The RESTORE Study)No drug interventionstreatment3completed
NCT02340299
Nasal HFOV Versus Nasal CPAP to Reduce Post-extubation pCO2No drug interventionstreatmentNot Availableterminated
NCT03422549
Diaphragmatic Electrical Activity in Preterm Infants on Non-Invasive VentilationNo drug interventionstreatmentNot Availableunknown_status
NCT02267018
Diaphragm Electrical Activity of Preterm Infants on nCPAP Versus NIHFVNo drug interventionstreatmentNot Availablecompleted
NCT02164734
Surfactant Via Endotracheal Tube vs. Laryngeal Mask Airway (LMA) in Preterm Neonates With Respiratory Distress Syndrometreatment4terminated
NCT05065424
Premedication for Less Invasive Surfactant Administration Study (PRELISA)treatment4recruiting
NCT04333563
Non-invasive Neurally Adjusted Ventilator Assist or Continuous Positive Airway Pressure in Preterm InfantsNo drug interventionstreatmentNot Availablecompleted
NCT00810186
Continuous Monitoring of Lung VentilationNo drug interventionsNot AvailableNot Availablecompleted
NCT02860325
NIV-NAVA Versus Nasal Continuous Positive Airway Pressure (nCPAP) or Non Synchronized NIPPVNo drug interventionstreatmentNot Availablecompleted
NCT02294630
Aerosolized Surfactant in Neonatal RDStreatment1 / 2completed
NCT04238273
High Flow Nasal Cannula Versus Nasal Continuous Positive Airway Pressure for Respiratory Support of Preterm NeonatesNo drug interventionsNot AvailableNot Availablecompleted
NCT00005776
Inhaled Nitric Oxide Study for Respiratory Failure in Newbornstreatment3terminated
NCT02452476
A Double Blind, Randomized, Controlled Study to Evaluate CHF 5633 (Synthetic Surfactant) and Poractant Alfa in Neonates With Respiratory Distress Syndrome (RDS) (POC)treatment2completed
NCT01688440
ETCare: Safety and Preliminary Efficacy TrialNo drug interventionsprevention0completed
NCT00244101
Delivery Room Management Trial of Premature Infants at High Risk of Respiratory Distress SyndromeNo drug interventionstreatment3completed
NCT05638568
Fast Assessment of Surfactant Deficiency in Preterm Infants to Speed up TreatmentNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT02788110
Work of Breathing During Non-invasive Ventilation in Premature NeonatesNo drug interventionstreatmentNot Availablecompleted
NCT05629910
NeO2Matic-Pilot TrialNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00486395
Will CPAP Reduce Length Of Respiratory Support In Premature Infants?No drug interventionsprevention3terminated
NCT00486850
Synchronized Intermittent Mandatory Ventilation (SIMV) Versus Nasal Intermittent Positive Pressure Ventilation (NIPPV) In Preterm Infants With Respiratory DistressNo drug interventionstreatment4completed
NCT03346343
Pulmonary Function Using Non-invasive Forced OscillometryNo drug interventionsdiagnosticNot Availablerecruiting
NCT04244890
Feasibility of Uninterrupted Infant Respiratory Support TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT04107090
Role of Lung Ultrasound In Assessment Of Recruitment Maneuvers In Ventilated Preterms With Respiratory Distress Syndrome and Its Correlation With Tracheal IL-6 LevelNo drug interventionsotherNot Availablecompleted
NCT04500353
Routine Or Selective Application of a Face Mask for Preterm Infants at Birth: the ROSA TrialNo drug interventionstreatmentNot Availablecompleted
NCT06007547
Prophylactic Minimally Invasive Surfactant Evaluationtreatment4recruiting
NCT05719298
Infant Respiratory Interface and Accessories Evaluation StudyNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT03165305
The Role of Sustained Inflation on Short Term Respiratory Outcomes in Term InfantsNo drug interventionspreventionNot Availablecompleted
NCT05961683
Evaluating Pressures During Non-invasive Ventilation Utilizing NIV Plus SoftwareNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04137783
ABCA3 Gene and RDS in Late Preterm and Term InfantsNo drug interventionsNot AvailableNot Availablecompleted
NCT05399628
LISA Catheter With Marked vs. Unmarked Tip in Extremely Low Birth Weight Infants With RDSNo drug interventionstreatmentNot Availablecompleted
NCT02852928
European Management Platform for Childhood Interstitial Lung Diseases - chILD-EU Register and BiobankNo drug interventionsNot AvailableNot Availablerecruiting
NCT05796128
NIPPV vs.nCPAP During LISA ProcedureNo drug interventionstreatmentNot Availablecompleted
NCT03081611
RAM Cannula VS Short Nasal Prongs for Delivering NIPPV in Preterm InfantsNo drug interventionstreatmentNot Availablecompleted
NCT02050971
Autologous Cord Blood Infusion for the Prevention and Treatment of Prematurity Complications In Preterm Neonatesprevention1unknown_status
NCT01203488
Vitamin A Supplementation for Extremely-Low-Birth-Weight Infantsprevention1 / 2completed
NCT01959009
High Frequency Oscillatory Ventilation Combined With Intermittent Sigh Breaths: Effects on Blood Oxygenation and Stability of OxygenationNo drug interventionstreatmentNot Availableunknown_status
NCT04264156
A Safety and Efficacy Study of Lucinactant for Inhalation in Preterm Neonates 26 to 32 Weeks Gestational Agetreatment2terminated
NCT00139256
Antepartum Betamethasone Treatment for Prevention of Respiratory Distress in Infants Born by Elective Cesarean Sectionprevention2 / 3terminated
NCT05230485
Optimal High CPAP Pressures in Preterm Neonates Post-extubationNo drug interventionssupportive_careNot Availableunknown_status
NCT03938532
Feasibility and Impact of Volume Targeted Ventilation in the Delivery RoomNo drug interventionstreatmentNot Availablerecruiting
NCT01042600
Randomized Controlled Trial of Surfactant Delivery Via Laryngeal Mask Airway (LMA) Versus Endotracheal IntubationNo drug interventionstreatment4completed
NCT05198375
Lung UltrasouNd Guided Surfactant Therapy in Preterm Infants (LUNG Study)No drug interventionstreatmentNot Availablerecruiting
NCT05961670
Application of Lung Near-Infrared Spectroscopy (NIRS) in Preterm InfantsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04914806
Infantile NO Replenishment as a New Therapeutic PossibilityNo drug interventionsNot AvailableNot Availablerecruiting
NCT03996317
Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing AbnormalitiesNo drug interventionstreatmentNot Availablewithdrawn
NCT04391634
Cerebral and Circulatory Effects of Neonatal Volume Targeted VentilationNo drug interventionstreatmentNot Availablecompleted
NCT01941524
Brain Oxygenation and Function of Preterm Newborns During Administration of Two Different Surfactant Preparationstreatment4completed
NCT05260424
Predictors for Nasal Intermittent Positive Pressure Ventilation Failure for Premature Infants With Respiratory Distress SyndromeNo drug interventionsNot AvailableNot Availablecompleted
NCT05594030
Thoracic Fluid Content by Electric Bioimpedance Versus Lung Ultrasound in Preterm Neonates With Respiratory DistressNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02168257
Neotech RAM Cannula Versus Conventional Binasal Prong Continuous Positive Airway Pressure (CPAP) to Treat Respiratory Distress in Low Birth Weight NeonatesNo drug interventionstreatmentNot Availableterminated
NCT04984057
Optimal Dose of Surfactant for Preterm Infants With Respiratory Distress SyndromeNo drug interventionstreatmentNot Availablerecruiting
NCT01526226
Patient Comfort During High Flow Nasal Cannula Versus Nasal Continuous Airway Pressure (CPAP)No drug interventionstreatmentNot Availablecompleted
NCT01255826
Ventilatory Management of the Preterm Neonate in the Delivery RoomNo drug interventionssupportive_care2completed
NCT00501982
Efficacy of Combining Prophylactic Curosurf With Early Nasal CPAP in Delivery Room: the Curpap Studyprevention4completed
NCT00005773
Early Inhaled Nitric Oxide for Respiratory Failure in Newbornstreatment3terminated
NCT01467076
Inhaled Prostaglandin E1 (IPGE1) for Hypoxemic Respiratory Failure (NHRF)treatment2terminated
NCT01242462
Feasibility of Mid-frequency Ventilation in Newborns With RDS: Randomized Crossover Pilot TrialNo drug interventionstreatment1 / 2completed
NCT05427929
Measuring Diaphragm Electrical Activity in Neonates Using a Smaller Inter-electrode DistanceNo drug interventionsdevice_feasibilityNot Availablerecruiting
NCT00598429
Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failuretreatment2withdrawn
NCT00215540
SURFAXIN® Treatment for Prevention of Bronchopulmonary Dysplasia (BPD) in Very Low Birth Weight (VLBW) Infants.prevention2terminated
NCT02332304
Amniotic Fluid Optical Density Determination as a Test for Assessment of Fetal Lung Maturity.No drug interventionsdiagnostic3completed
NCT01206946
Efficacy of Antenatal Steroids in Reducing Respiratory Morbidities in Late Preterm Infantsprevention2unknown_status
NCT03121612
Comparison of CPAP Machines With Reusable vs Disposable CircuitsNo drug interventionstreatmentNot Availableterminated
NCT03366714
RAM Cannula Versus Short Bi-nasal Cannula in Respiratory Distress SyndromeNo drug interventionssupportive_careNot Availablecompleted
NCT00556738
Intrapulmonary Percussive Ventilation (IPV) Versus Nasal Continuous Positive Airway Pressure Ventilation (nCPAP) in Transient Respiratory Distress of the NewbornNo drug interventionstreatmentNot Availablecompleted
NCT01102543
Observational Study on the Prophylactic Use of Curosurf in Neonatal Respiratory Distress Syndrome (RDS)No drug interventionsNot AvailableNot Availablecompleted
NCT00828243
Genetic Regulation of Surfactant DeficiencyNot AvailableNot Availablecompleted