Idiopathic Short Stature (ISS) (DBCOND0035250)

Identifiers

Synonyms
ISS- Idiopathic Short Stature / Short Stature, Idiopathic / Idiopathic Short Stature / Idiopathic short stature (disorder) / Short stature (child) / Short stature / Stature short / Short stature disorder (disorder) / Small stature

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Somatotropin
A recombinant human growth hormone used as replacement therapy in various conditions of growth failure, growth hormone deficiency, and weakness in children and adults.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT04962360
The Effect of Nutritional Formula Supplementation on Linear Growth of Growth Hormone (GH) Treated Prepubertal Children With Idiopathic Short Stature (ISS) After 2 Years From the Beginning of GH-therapyNo drug interventionstreatmentNot Availablerecruiting
NCT03015909
Evaluation of the Ease of Use, Preference, and Safety of EutropinPen Inj.treatment4completed
NCT02412943
Pappalysin 2 (PAPP-A2) Enzyme ReplacementNo drug interventionsbasic_science1completed
NCT00355030
Somatropin + Leuprorelin vs Somatropin Alone in Pubertal Children With Idiopathic Short StatureNo drug interventionstreatment3completed
NCT01786902
Efficacy and Safety of DA-3002 in Children With Idiopathic Short StatureNo drug interventionstreatment3completed
NCT01504802
Pharmacodynamics of CNP During Growth Hormone TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT00263445
Constructing an Insulin-Like Growth Factor-based Prediction ModelNo drug interventionsNot AvailableNot Availableterminated
NCT00121875
Study to Identify Markers of Insulin Resistance During Growth Hormone Treatment for Short StatureNot AvailableNot Availableterminated
NCT05858606
Multidisciplinary Evaluation and a Genome-wide Analysis in a Cohort of Idiopathic Short Stature PatientsNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT00488124
Growth Response in Short Children Suffering From a Disease With Growth Retardation and Treated With SomatropinNo drug interventionstreatment2completed
NCT01248416
Aromatase Inhibitors, Alone And In Combination With Growth Hormone In Adolescent Boys With Idiopathic Short StatureNo drug interventionstreatment3completed
NCT01070173
Ghrelin Levels in Children With Poor GrowthNo drug interventionsNot AvailableNot Availablecompleted
NCT05894876
A Study of the Genetic Basis of Response to Growth Hormone Treatment in Children With Idiopathic Short StatureNo drug interventionsNot AvailableNot Availablerecruiting
NCT01746862
A Phase 3 Study to Evaluate the Safety and Efficacy of Saizen® in Children With Idiopathic Short Stature (ISS)No drug interventionstreatment3completed
NCT00840944
A 4 Year Combination Therapy of Growth Hormone and (GnRH) Agonist in Children With a Short Predicted HeightNo drug interventionstreatment4active_not_recruiting
NCT01778023
Efficacy and Safety of Recombinant Human Growth Hormone on Height Velocity in Subjects With Idiopathic Short StatureNo drug interventionstreatment3completed
NCT04798690
Long-term Safety and Effectiveness of Growtropin®-II Treatment in Children With Short StatureNo drug interventionsNot AvailableNot Availablerecruiting
NCT00965484
Genotropin Study Assessing Use of Injection PenNo drug interventionstreatment3completed
NCT06309979
A Study to Assess Growth in Children With Idiopathic Short StatureNo drug interventionsNot AvailableNot Availablerecruiting
NCT00396097
Individualized, Target-Driven Treatment Of Children With Idiopathic Short StatureNo drug interventionstreatment3completed
NCT02973061
The Impact of the Use of Recombinant Human Growth Hormone on ADHD Characteristics in Children and AdolescentsNo drug interventionsNot AvailableNot Availablerecruiting
NCT00710307
Epidemiology Study on Insulin-like Growth Factor-1 in Children With Idiopathic Short Stature (EPIGROW Study)No drug interventionsNot AvailableNot Availablecompleted
NCT05838885
A Trial of YPEG-rhGH in Children With Short StatureNo drug interventionstreatment2completed
NCT00262249
Effect of Growth Hormone in Children With Growth Hormone Deficiencytreatment3completed
NCT04020913
Skeletal Muscle Effects of GH in BoysNot AvailableNot Availableactive_not_recruiting
NCT01246219
Short Stature Related DistressNo drug interventionstreatment4completed
NCT00458263
Biochemical Markers of Growth Response to Growth Hormone Treatment in Children With Idiopathic Short StatureNo drug interventionstreatment4completed
NCT01401244
Bioequivalence of Two Somatropin Products (Norditropin® Versus Genotropin®) in Healthy Adult VolunteersNo drug interventionstreatment1completed
NCT01543867
Safety and Efficacy of Long-term Somatropin Treatment in ChildrenNo drug interventionsNot AvailableNot Availablecompleted
NCT01438801
Predictive Value of the Insulin-like Growth Factor-1 (IGF-1) Generation Test for the Growth Response to Growth Hormone Treatment (PRED-IGF)No drug interventionsdiagnostic4withdrawn
NCT01604395
Long-term Safety and Effectiveness of Growth Hormone With GHD, TS, CRF, SGA , ISS and PWS in ChildrenNo drug interventionsNot AvailableNot Availablerecruiting
NCT06382155
A Phase 2 Study of Vosoritide in Children With Idiopathic Short StatureNo drug interventionstreatment2not_yet_recruiting