NCT05661188
Tiraglolumab Atezolizumab and Chemoradiotherapy in Localized Anal Carcinoma (TIRANUS) treatment 2 recruiting NCT05201105
Tumor Recurrence After Abdominal-perineal Amputation in Squamous Cell Carcinoma of the Anus No drug interventions Not Available Not Available completed NCT04472429
Carboplatin-paclitaxel With Retifanlimab or Placebo in Participants With Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (POD1UM-303/InterAACT 2). treatment 3 active_not_recruiting NCT03870607
Prebiotics and Probiotics During Definitive Treatment With Chemotherapy-radiotherapy SCC of the Anal Canal (BISQUIT) No drug interventions treatment 2 recruiting NCT04462042
Proton Versus Photon Therapy in Anal Squamous Cell Carcinoma No drug interventions treatment Not Available recruiting NCT04429542
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients with EGFR-driven Advanced Solid Tumors treatment 1 recruiting NCT01382745
Nimotuzumab With Radiotherapy in the Treatment of Anal Canal Cancers treatment 2 terminated NCT03597295
A Study of INCMGA00012 in Squamous Carcinoma of the Anal Canal Following Platinum-Based Chemotherapy (POD1UM-202) treatment 2 completed NCT03944252
Cetuximab + Avelumab or Avelumab Alone for Unresectable, Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (SCCAC) Progressed After at Least One Line of Systemic Treatment (CARACAS) treatment 2 unknown_status NCT04894370
Combination of Spartalizumab, mDCF and Radiotherapy in Patients With Metastatic Squamous Cell Anal Carcinoma No drug interventions treatment 2 recruiting NCT04580485
INCB106385 Alone or in Combination With Immunotherapy in Advanced Solid Tumors treatment 1 completed NCT04166318
Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study treatment 2 recruiting NCT03712566
Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic Therapy No drug interventions Not Available Not Available active_not_recruiting NCT02314169
Nivolumab With or Without Ipilimumab in Treating Patients With Refractory Metastatic Anal Canal Cancer treatment 2 active_not_recruiting NCT03690921
Linear Energy Transfer (LET)-Optimized Intensity Modulated Proton Therapy (IMPT) as a Component of Definitive Chemoradiation for Newly Diagnosed Squamous Cell Carcinoma of the Anal Canal: a Feasibility Trial treatment 2 completed NCT04499352
A Study to Test BI 754091 Alone or in Combination With BI 836880 in People Who Have Advanced Anal Cancer treatment 2 withdrawn NCT04929028
Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer treatment 2 recruiting NCT02437851
Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection No drug interventions treatment 2 active_not_recruiting NCT02560298
Cisplatin and Fluorouracil Compared With Carboplatin and Paclitaxel in Treating Patients With Inoperable Locally Recurrent or Metastatic Anal Cancer treatment 2 active_not_recruiting NCT02407561
Prospective Validation Study for the Proprietary Rectal and Anal Cancer Protein Expression Assays No drug interventions Not Available Not Available terminated NCT05060471
PD-1 Blockade Combined With Chemotherapy Followed by Concurrent Immunoradiotherapy for Locally Advanced SCCA Patients treatment 2 enrolling_by_invitation NCT01285778
Vectibix for the Treatment of Anal Cancer treatment 2 completed NCT05374252
Chemoradiotherapy Combined With or Without PD-1 Blockade in Anal Canal Squamous Carcinoma Patients No drug interventions treatment 3 recruiting NCT05438836
Re-optimization Based Online Adaptive Radiotherapy of Anal Cancer No drug interventions Not Available Not Available recruiting NCT05328765
A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection No drug interventions Not Available Not Available recruiting NCT05582031
Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancers treatment 2 withdrawn NCT05130073
4-Point Therapy Response Score With PET/CT for Anal Squamous Cell Cancer No drug interventions Not Available Not Available completed NCT01115790
A Phase 1 Study in Participants With Advanced Cancer treatment 1 completed NCT04596033
TiTAN-1: Safety, Proliferation and Persistence of GEN-011 Autologous Cell Therapy treatment 1 terminated NCT06050707
MR-Adaptive Radiation Therapy for Anal Cancer With EScalated-Treatment in a Risk-Optimized Approach No drug interventions treatment 2 recruiting NCT04616196
Study of NKTR 255 in Combination With Cetuximab in Solid Tumors treatment 1 / 2 completed NCT05838391
Adaptive Radiation in Anal Cancer other Not Available recruiting NCT01807546
Oral Rigosertib for Squamous Cell Carcinoma treatment 2 completed NCT03849469
A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors treatment 1 completed NCT03386500
Safety Study of BMX-001 (Radio-protector) in Patients With Newly Diagnosed Anal Cancer treatment 1 / 2 recruiting NCT06236464
Identification of the Pathogenetic Mechanisms Underlying Squamous Cell Carcinomas No drug interventions Not Available Not Available recruiting NCT02162641
Study to Determine the Feasibility of Sentinel Node Biopsy in Patients With Anal Cancer No drug interventions Not Available Not Available withdrawn NCT02051868
International Multicentre Study in Advanced Anal Cancer Comparing Cisplatin Plus 5 FU vs Carboplatin Plus Weekly Paclitaxel treatment 2 unknown_status NCT03517488
A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors treatment 1 completed NCT03221400
PEN-866 in Patients With Advanced Solid Malignancies treatment 1 / 2 unknown_status NCT03894618
SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas No drug interventions treatment 1 completed