Anal Squamous Cell Carcinoma (DBCOND0046728)

Identifiers

Synonyms
Squamous Cell Carcinoma of the Anal Canal / Anal Cancer Squamous Cell / Squamous Cell Carcinoma of Anal Canal / Squamous Cell Anal Carcinoma / Anal Canal Squamous Cell Carcinoma / Squamous Cell Anal Cancer / Anal Cancer, Squamous Cell Carcinoma / Squamous Cell Carcinoma of the Anus / Anal squamous cell carcinoma / Squamous cell carcinoma of anal margin (disorder) / Squamous cell carcinoma of anal skin / Anal margin carcinoma NOS / Metastatic anal adenocarcinoma / Anal carcinoma NOS / Anal Cancer / Anal carcinoma

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05661188
Tiraglolumab Atezolizumab and Chemoradiotherapy in Localized Anal Carcinoma (TIRANUS)treatment2recruiting
NCT05201105
Tumor Recurrence After Abdominal-perineal Amputation in Squamous Cell Carcinoma of the AnusNo drug interventionsNot AvailableNot Availablecompleted
NCT04472429
Carboplatin-paclitaxel With Retifanlimab or Placebo in Participants With Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (POD1UM-303/InterAACT 2).treatment3active_not_recruiting
NCT03870607
Prebiotics and Probiotics During Definitive Treatment With Chemotherapy-radiotherapy SCC of the Anal Canal (BISQUIT)No drug interventionstreatment2recruiting
NCT04462042
Proton Versus Photon Therapy in Anal Squamous Cell CarcinomaNo drug interventionstreatmentNot Availablerecruiting
NCT04429542
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients with EGFR-driven Advanced Solid Tumorstreatment1recruiting
NCT01382745
Nimotuzumab With Radiotherapy in the Treatment of Anal Canal Cancerstreatment2terminated
NCT03597295
A Study of INCMGA00012 in Squamous Carcinoma of the Anal Canal Following Platinum-Based Chemotherapy (POD1UM-202)treatment2completed
NCT03944252
Cetuximab + Avelumab or Avelumab Alone for Unresectable, Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (SCCAC) Progressed After at Least One Line of Systemic Treatment (CARACAS)treatment2unknown_status
NCT04894370
Combination of Spartalizumab, mDCF and Radiotherapy in Patients With Metastatic Squamous Cell Anal CarcinomaNo drug interventionstreatment2recruiting
NCT04580485
INCB106385 Alone or in Combination With Immunotherapy in Advanced Solid Tumorstreatment1completed
NCT04166318
Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Studytreatment2recruiting
NCT03712566
Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic TherapyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02314169
Nivolumab With or Without Ipilimumab in Treating Patients With Refractory Metastatic Anal Canal Cancertreatment2active_not_recruiting
NCT03690921
Linear Energy Transfer (LET)-Optimized Intensity Modulated Proton Therapy (IMPT) as a Component of Definitive Chemoradiation for Newly Diagnosed Squamous Cell Carcinoma of the Anal Canal: a Feasibility Trialtreatment2completed
NCT04499352
A Study to Test BI 754091 Alone or in Combination With BI 836880 in People Who Have Advanced Anal Cancertreatment2withdrawn
NCT04929028
Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancertreatment2recruiting
NCT02437851
Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV InfectionNo drug interventionstreatment2active_not_recruiting
NCT02560298
Cisplatin and Fluorouracil Compared With Carboplatin and Paclitaxel in Treating Patients With Inoperable Locally Recurrent or Metastatic Anal Cancertreatment2active_not_recruiting
NCT02407561
Prospective Validation Study for the Proprietary Rectal and Anal Cancer Protein Expression AssaysNo drug interventionsNot AvailableNot Availableterminated
NCT05060471
PD-1 Blockade Combined With Chemotherapy Followed by Concurrent Immunoradiotherapy for Locally Advanced SCCA Patientstreatment2enrolling_by_invitation
NCT01285778
Vectibix for the Treatment of Anal Cancertreatment2completed
NCT05374252
Chemoradiotherapy Combined With or Without PD-1 Blockade in Anal Canal Squamous Carcinoma PatientsNo drug interventionstreatment3recruiting
NCT05438836
Re-optimization Based Online Adaptive Radiotherapy of Anal CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT05328765
A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV InfectionNo drug interventionsNot AvailableNot Availablerecruiting
NCT05582031
Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancerstreatment2withdrawn
NCT05130073
4-Point Therapy Response Score With PET/CT for Anal Squamous Cell CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT01115790
A Phase 1 Study in Participants With Advanced Cancertreatment1completed
NCT04596033
TiTAN-1: Safety, Proliferation and Persistence of GEN-011 Autologous Cell Therapytreatment1terminated
NCT06050707
MR-Adaptive Radiation Therapy for Anal Cancer With EScalated-Treatment in a Risk-Optimized ApproachNo drug interventionstreatment2recruiting
NCT04616196
Study of NKTR 255 in Combination With Cetuximab in Solid Tumorstreatment1 / 2completed
NCT05838391
Adaptive Radiation in Anal CancerotherNot Availablerecruiting
NCT01807546
Oral Rigosertib for Squamous Cell Carcinomatreatment2completed
NCT03849469
A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumorstreatment1completed
NCT03386500
Safety Study of BMX-001 (Radio-protector) in Patients With Newly Diagnosed Anal Cancertreatment1 / 2recruiting
NCT06236464
Identification of the Pathogenetic Mechanisms Underlying Squamous Cell CarcinomasNo drug interventionsNot AvailableNot Availablerecruiting
NCT02162641
Study to Determine the Feasibility of Sentinel Node Biopsy in Patients With Anal CancerNo drug interventionsNot AvailableNot Availablewithdrawn
NCT02051868
International Multicentre Study in Advanced Anal Cancer Comparing Cisplatin Plus 5 FU vs Carboplatin Plus Weekly Paclitaxeltreatment2unknown_status
NCT03517488
A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumorstreatment1completed
NCT03221400
PEN-866 in Patients With Advanced Solid Malignanciestreatment1 / 2unknown_status
NCT03894618
SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or LymphomasNo drug interventionstreatment1completed