Plasma Volume Replacement (DBCOND0047264)

Identifiers

Synonyms

Not Available

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Calcium chloride	An ionic compound used for the treatment of hypocalcemia and hyperkalemia, and as an antidote to magnesium intoxication due to overdosage of magnesium sulfate.	Protein S100-A13target
Dextran	A low molecular weight dextran used as an adjunctive treatment of shock or impending shock due to hemorrhage, burns, surgery or other trauma, as well as the prophylaxis of venous thrombosis and pulmonary embolism during high-risk medical procedures.	No drug targets
Gelatin	Gelatin is used for weight loss and for treating osteoarthritis, rheumatoid arthritis, and brittle bones (osteoporosis). Some people also use it for strengthening bones, joints, and fingernails. Gelatin is also...	No drug targets
Potassium chloride	A potassium salt used to treat hypokalemia.	Solute carrier family 12 member 2target Solute carrier family 12 member 1target Solute carrier family 12 member 5target Solute carrier family 12 member 6target Solute carrier family 12 member 7target Solute carrier family 12 member 4target Solute carrier family 12 member 2transporter Solute carrier family 12 member 1transporter Solute carrier family 12 member 5transporter Solute carrier family 12 member 6transporter Solute carrier family 12 member 7transporter Solute carrier family 12 member 4transporter
Sodium chloride	An ingredient found in a variety of nutritional products as a source of electrolytes and water.	No drug targets
Succinylated gelatin	A plasma volume expander indicated alone or in combination with blood transfusions.	No drug targets

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT01304433	Safety Profile of Hydroxyethyl Starch	Hydroxyethyl Starch	Not Available	Not Available	completed
NCT01117649	Plasma Volume Replacement (PVR) Therapy With Colloid and Crystalloid Solutions	Hydroxyethyl Starch	treatment	4	completed