NCT06350487
The Efficacy of Enavogliflozin in Heart Failure With Preserved Ejection Fraction treatment 4 not_yet_recruiting NCT05638230
Relative Importance of Cardiovascular Risk Factors and Echocardiographic Parameters Affecting Left Atrial Strain No drug interventions Not Available Not Available recruiting NCT03197350
Characterization of Heart Failure With Preserved Ejection Fraction No drug interventions other Not Available recruiting NCT05745337
Atrial Fibrillation: Chronic Beta-blocker Use Versus As-needed Rate Control Guided by Implantable Cardiac Monitor treatment 1 recruiting NCT04826159
IMPROVE-DiCE: Study to Evaluate Effect of IMB-1018972 on Cardiac Energetics in T2DM & Obesity (Pt 1) With HFpEF (Pt 2) No drug interventions treatment 2 recruiting NCT06312748
Novel Approaches for Improving Vascular Function in Veterans With HFpEF treatment 1 recruiting NCT06405126
Validation of a Machine Learning Predictive Model to Distinguish Post-capillary Pulmonary Hypertension No drug interventions Not Available Not Available recruiting NCT05784753
HEART Camp Connect -Promoting Exercise in Adults With Heart Failure With Preserved Ejection Fraction No drug interventions treatment Not Available recruiting NCT05637398
Colchicine in Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction treatment 1 / 2 recruiting NCT06125925
Catheter Ablation in Atrial Fibrillation Patients With HFpEF (STABLE-SR IV Trial) No drug interventions treatment Not Available recruiting NCT06514820
Exercise Magnetic Resonance Imaging in Patients With Obesity Associated Heart Failure No drug interventions Not Available Not Available recruiting NCT05610410
Peripheral Microvascular Blood Flow in ANOCA No drug interventions Not Available Not Available recruiting NCT02145351
Efficacy Study of Pacemakers to Treat Slow Heart Rate in Patients With Heart Failure No drug interventions treatment Not Available completed NCT04434664
BLOCKade of Calcium Channels and Beta Adrenergic Receptors for the Treatment of Hypertension in HFpEF treatment 4 recruiting NCT05826821
Biomarkers in HF: Circulating Biomarkers of Fibrosis and Cardiovascular Disease Not Available Not Available completed NCT05312021
Selective PDE9 Inhibition With IMR-687 in Adults With Heart Failure With Preserved Ejection Fraction treatment 2 withdrawn NCT04986202
Study to Evaluate the Efficacy and Safety of AZD4831 in Participants With Heart Failure With Left Ventricular Ejection Fraction > 40% treatment 2 / 3 completed NCT03057002
UTSW HP [13-C] Pyruvate Injection in HCM No drug interventions Not Available Not Available recruiting NCT06080802
The Effect of Addition of Metformin to SGLT2 In Diabetic Patients With Heart Failure With Preserved Ejection Fraction treatment 2 / 3 not_yet_recruiting NCT04757584
Pilot Deprescribing N-of-1 Trials for Beta-blockers in HFpEF other 4 completed NCT02901184
Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction treatment 3 recruiting NCT05991284
Sacubitril-Valsartan in Heart Failure With Preserved Ejection Fraction and Secondary Mitral Valve Regurgitation treatment 4 recruiting NCT05723679
Targeting Breathing Limitations to Improve Functional Outcomes in HFpEF No drug interventions other Not Available recruiting NCT03351179
Predictors and Outcomes of In-hospital HFpEF in AMI Patients No drug interventions Not Available Not Available unknown_status NCT04063579
Cardiac Magnetic Resonance Assessment for Heart Failure With Preserved Ejection Fraction No drug interventions diagnostic Not Available completed NCT05649787
Effects of a Supervised Training Program on Functional Capacity in Patients With HFpEF and Chronotropic Incompetence No drug interventions treatment Not Available active_not_recruiting NCT05838287
Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants treatment 4 recruiting NCT05600387
Empagliflozin on the Function of Left Atrium in Heart Failure With Mildly Reduced or Preserved Ejection Fraction treatment 4 enrolling_by_invitation NCT03340233
Understanding the Mechanisms of Diastolic Dysfunction No drug interventions diagnostic Not Available withdrawn NCT04970953
Diastolic Exercise Stress Testing in Heart Failure No drug interventions Not Available Not Available terminated NCT04998877
Physical Activity, Cardiac and Skeletal Muscle Energetics in Healthy Subjects and HFpEF Patients No drug interventions Not Available Not Available recruiting NCT02078947
Optimizing Exercise Training in Prevention and Treatment of Diastolic Heart Failure No drug interventions treatment Not Available completed NCT06369298
Study of JK07 in Patients With Chronic Heart Failure No drug interventions treatment 2 recruiting NCT04913805
Matching Perfusion and Metabolic Activity in HFpEF treatment 2 recruiting NCT05715697
Renal Denervation in Patients With Chronic Heart Failure With Preserved Ejection Fraction No drug interventions treatment Not Available recruiting NCT04767061
Impact of Beta-blockers on Physical Function in HFpEF other 4 completed NCT05991128
The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iron Deficiency on Exercise Capacity and Quality of Life treatment 4 recruiting NCT05839028
Mechanisms of LV Remodeling in Hypertensive Patients Working on a Rotational Expeditionary Basis in the Arctic No drug interventions Not Available Not Available active_not_recruiting NCT03153111
A Study to Evaluate Whether Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease treatment 2 completed NCT01920711
Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients With Preserved Ejection Fraction treatment 3 completed NCT06101693
Biomarkers in Patients With Suspected HFpEF No drug interventions Not Available Not Available recruiting NCT05219188
PErirenal Adipose Tissue and RenaL Hemodynamics in Patients With Heart Failure With Preserved Ejection Fraction No drug interventions Not Available Not Available unknown_status NCT05828888
CHIP in Endothelial Dysfunction Associated With HEpEF No drug interventions Not Available Not Available not_yet_recruiting NCT06208007
Arterial Stiffening as a Predictor for Diastolic Cardiac Dysfunction and HFpEF No drug interventions Not Available Not Available recruiting NCT06228807
Clinical Characteristics and Predictors of Adverse Outcomes in HFpEF No drug interventions Not Available Not Available completed NCT04239807
3-Month Home-based Training With Whole Body Vibration (WBV) Device in Patients With Heart Failure and Preserved Ejection Fraction (GALILEO-HFpEF-HOME) (GALILEOHOME) No drug interventions treatment Not Available unknown_status NCT04945707
Impact of Intravenous Iron Repletion On Mechanisms of Exercise InTolerance in HFpEF (IRONMET-HFpEF) treatment 4 recruiting NCT05064709
Assessment of CCM in HF With Higher Ejection Fraction No drug interventions treatment Not Available recruiting NCT04820556
Gut Microbiota in Chronic Noncommunicable Diseases No drug interventions Not Available Not Available completed NCT05053256
The Relationship Between Heart Function and Metabolism in HFpEF Patients No drug interventions Not Available Not Available unknown_status NCT05508256
CAtheter-Based Ablation of Atrial Fibrillation Compared to Conventional Treatment in Patients With Heart Failure With Preserved Ejection Fraction No drug interventions treatment 4 recruiting NCT03254485
A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejection Fraction (HFpEF) treatment 2 completed NCT04739215
Effects of SGLT2 Inhibition on the Mechanisms of Cardiac Damage in the Diabetic Patient With HFpEF treatment 4 unknown_status NCT06309537
Chemoreflex Sensitivity in HFpEF No drug interventions Not Available Not Available not_yet_recruiting NCT06201832
Cardiac Amyloidosis in HFpEF Tunisian Patients No drug interventions Not Available Not Available recruiting NCT04404452
Heart Failure Monitoring With Eko Electronic Stethoscopes No drug interventions Not Available Not Available terminated NCT03226652
Heart Function in Patients Assessed for Sleep Apnoea No drug interventions Not Available Not Available completed NCT05093959
Metformin for Older Patients With Heart Failure With Preserved Ejection Fraction treatment 2 recruiting NCT05002075
Efficacy of an m-Health Cardiac Rehabilitation Program in Heart Failure With Preserved Ejection Fraction No drug interventions treatment Not Available completed NCT03837470
Evaluation of Renal Sodium Excretion After Salt Loading in Heart Failure With Preserved Ejection Fraction basic_science 0 completed NCT06510270
Dapagliflozin in Reducing Epicardial Adipose Tissue in Heart Failure with Preserved Ejection Fraction No drug interventions treatment Not Available not_yet_recruiting NCT05159570
Modulation of Circulating Levels of the Ketone Body 3-hydroxybutyrate in Patients With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction: Metabolic Effects. (KETO-HFpEF-Metabolic) No drug interventions treatment Not Available completed NCT05279742
Enhancing the Natriuretic Peptide System in HFpEF treatment 1 / 2 enrolling_by_invitation NCT04235699
Ketogenic Diet in Patients With Heart Failure No drug interventions treatment Not Available terminated NCT04506606
Cardiac Rehab Effects in HFpEF No drug interventions treatment Not Available recruiting NCT05057806
SGLT2 Inhibitors, Ketones, and Cardiovascular Benefit Research Plan basic_science 0 recruiting NCT06486649
Application of Multimodal Large Language Model in HFpEF No drug interventions Not Available Not Available recruiting NCT04886713
Adipose Tissue Inflammation in HFpEF No drug interventions Not Available Not Available unknown_status NCT04745013
PeRsonalIzed remOtely Guided Preventive exeRcIse Therapy for a healThY Heart No drug interventions prevention Not Available recruiting NCT03619213
Dapagliflozin Evaluation to Improve the LIVEs of Patients With PReserved Ejection Fraction Heart Failure. treatment 3 completed NCT01354613
Reduced Contractile Reserve: a Therapeutic Target in Heart Failure With Preserved Ejection Fraction(HFpEF) treatment Not Available completed NCT04019613
Assessment of Pulmonary Congestion During Cardiac Hemodynamic Stress Testing No drug interventions diagnostic Not Available terminated NCT05584319
EMPAGUM: Effects of Empagliflozin on Gut Microbiota in Heart Failure With a Preserved Ejection Fraction treatment 4 enrolling_by_invitation NCT05651919
PBMC as Biomarkers of Diabetic Cardiomyopathy No drug interventions Not Available Not Available recruiting NCT06532019
Clinical Study of Active Intervention in High-risk HFpEF Patients No drug interventions other Not Available not_yet_recruiting NCT04064541
Virtual Visits to Optimize Research Trial Offerings to HF Patients No drug interventions health_services_research Not Available completed NCT04964817
HFpEF and Symptomatic Obstructive Iliofemoral Venous Disease Study No drug interventions Not Available Not Available terminated NCT05322616
Single-Ascending Dose Study of JK07 in Subjects With HFpEF No drug interventions treatment 1 withdrawn NCT03550235
Exploration of Dyspnea at Non-high Brain Natriuretic Peptide (BNP) No drug interventions Not Available Not Available unknown_status NCT04398563
Heart Failure in Norway: Clinical Characteristics, Mortality and Health Care Resource Use No drug interventions Not Available Not Available unknown_status NCT00840463
Safety and Efficacy Trial to Treat Diastolic Heart Failure Using Ambrisentan diagnostic 4 terminated NCT05496439
Study of the Prognosis of Patients With Heart Failure With Preserved Ejection Fraction No drug interventions Not Available Not Available completed NCT06282822
Shear Wave Elastography for Diagnosis of Heart Failure With Preserved Ejection Fraction No drug interventions Not Available Not Available not_yet_recruiting NCT05822622
Relationship Between Heart Failure With Preserved Ejection Fraction and Nonalcoholic Fatty Liver Disease. No drug interventions Not Available Not Available not_yet_recruiting NCT05585125
A Preliminary Study for INFORMED No drug interventions other 4 recruiting NCT03160625
Evaluation of Rate Adaptive Pacing on Chronotropic Response in Preserved Ejection Fraction HF No drug interventions treatment Not Available withdrawn NCT05376748
Exercise Capacity Before and After AF Ablation in Patients With HFpEF No drug interventions Not Available Not Available recruiting NCT04535726
The Relationship Between Blood Pressure and Arterial Stiffness in HFpEF Patients With Different Levels of Obesity No drug interventions Not Available Not Available completed NCT05731466
Exercise Right Ventricular Coupling in HFpEF No drug interventions diagnostic Not Available recruiting NCT01288365
The Impact of Exercise Training on Functional Capacity in Heart Failure No drug interventions treatment Not Available unknown_status NCT05953831
Reverse Remodeling Effects of CDR132L in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction and Cardiac Hypertrophy No drug interventions treatment 2 withdrawn NCT04862273
Native T1 CMR Imaging for Diagnosis of Cardiac Amyloidosis No drug interventions Not Available Not Available active_not_recruiting NCT04788576
Distribution and Clinical Implication of CMD in Patients With HFpEF Without Significant CAD No drug interventions Not Available Not Available recruiting NCT06015776
Purinergic Signaling and the Postmenopausal Heart No drug interventions Not Available Not Available recruiting NCT05752760
Pilot Study Lp299v Supplementation in Chronic Heart Failure No drug interventions basic_science Not Available recruiting NCT05393362
Effectiveness of a Cardiac Rehabilitation Program in Elderly Patients With Heart Failure. No drug interventions treatment Not Available recruiting NCT03037580
Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction treatment 3 terminated NCT04644692
Effort-Lung Ultra Sound No drug interventions Not Available Not Available completed NCT05582044
Exercise Lower-body Negative Pressure in Heart Failure With Preserved Ejection Fraction No drug interventions treatment Not Available recruiting NCT04237701
Real-Time Monitoring of Heart Failure Across the Yale New Haven Health System No drug interventions Not Available Not Available recruiting NCT05490901
The Prognostic Role and Diagnostic Efficacy of Exercise Right Heart Catheterization With a Simultaneous Echocardiography in Patients With Dyspnea on Exertion No drug interventions Not Available Not Available recruiting NCT03066804
A Randomized, Double-blind Controlled Study Comparing LCZ696 to Medical Therapy for Comorbidities in HFpEF Patients treatment 3 completed NCT05139472
Impact of Empagliflozin on Functional Capacity in Heart Failure With Preserved Ejection Fraction treatment 3 completed NCT04894968
Prediction of the Development of Heart Failure With Preserved Ejection Fraction No drug interventions Not Available Not Available unknown_status NCT02053246
Improving Treatment Personalization of Pulmonary Hypertension Associated With Diastolic Heart Failure treatment 4 terminated NCT04395846
Heart Failure and Preserved Ejection Fraction: Observation of Its Progression and Prognosis (HOPP-BERN) No drug interventions Not Available Not Available recruiting NCT06046612
Empagliflozin for Peripheral Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction treatment 4 recruiting NCT05878912
The Effect of Obesity and Weight Loss in Heart Failure With Preserved Ejection Fraction No drug interventions treatment Not Available recruiting NCT03506412
Circulating NEP and NEP Inhibition Study in Heart Failure With Preserved Ejection Fraction treatment 4 completed NCT05833581
Consistently Assess Signs and Symptom of Heart Failure No drug interventions other Not Available recruiting NCT05553314
Carvedilol in HF With Preserved EF treatment 4 recruiting NCT04424914
Global Prevalence of ATTR-CM in Participants With HFpEF No drug interventions screening Not Available terminated NCT06353750
Intracellular Magnesium and Heart Failure No drug interventions Not Available Not Available not_yet_recruiting NCT05796050
Sex Related Differences in Cardiac Function No drug interventions Not Available Not Available recruiting NCT06309550
Provocative Tests for HFpEF No drug interventions Not Available Not Available recruiting NCT06576050
WeighT LOSS Surgery and Comprehensive Cardiometabolic Responses to to EXercise No drug interventions Not Available Not Available active_not_recruiting NCT05464238
Training in HFpEF-PH No drug interventions treatment Not Available not_yet_recruiting NCT06465043
HFPEF-project: Heart Failure Phenotyping - Exploring the Fingerprints No drug interventions Not Available Not Available not_yet_recruiting NCT06081543
Ketogenic Diet vs Mixed Diet in Patients With Heart Failure No drug interventions basic_science Not Available recruiting NCT05676684
Dapagliflozin With or Without Spironolactone for HFpEF treatment 2 / 3 active_not_recruiting NCT01505179
The Effects of Ranolazine on Exercise Capacity in Patients With Heart Failure With Preserved Ejection Fraction treatment Not Available completed NCT05030987
Renal Denervation to Treat Heart Failure With Preserved Ejection Fraction No drug interventions treatment Not Available recruiting NCT05058833
Prognostic Impact of Cardiac Diastolic Function and Coronary Microvascular Function No drug interventions Not Available Not Available unknown_status NCT05174351
Beta-blocker Discontinuation in Heart Failure With Preserved Ejection Fraction No drug interventions treatment Not Available unknown_status NCT05753553
Incidence and Echocardiographic Predictors of HFpEF in High-Risk Population Afferent to Italian Echo-labs Network No drug interventions Not Available Not Available recruiting NCT05789147
Transcutaneous Vagus Nerve Stimulation in Heart Failure No drug interventions treatment Not Available recruiting NCT04730947
Dapagliflozin (DAPA) Effects in HFpEF treatment 2 completed NCT04592445
Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF No drug interventions treatment Not Available unknown_status NCT04318145
Study to Evaluate Sex Differences in the Acute Effects of PL-3994 in Heart Failure Subjects treatment 2 unknown_status NCT06249945
EMPAgliflozin in Heart Failure With PReserved Ejection Fraction and End Stage Renal Disease treatment 4 not_yet_recruiting NCT06114498
Hospital Register of Decompensated Heart Failure With Preserved Ejection Fraction No drug interventions Not Available Not Available recruiting NCT06576297
Novel Respiratory Training as Part of Palliative Care for Older Adults With Heart Failure No drug interventions treatment Not Available recruiting NCT05409183
Effectiveness of CRD-740 in Heart Failure No drug interventions treatment 2 terminated NCT06078683
Effects of Ketone Ester Consumption on Exercise Tolerance and Cardiac Function No drug interventions basic_science Not Available recruiting NCT06377761
Study on Heart Failure With Preserved Ejection Fraction With Qishen Granules No drug interventions treatment Not Available recruiting NCT04163861
Frequency and Magnitude of Subclinical Systolic Dysfunction by Strain Imaging in Heart Failure With Preserved Ejection Fraction No drug interventions Not Available Not Available completed NCT04455828
Wearable Remote Monitoring of Heart Rate and Respiratory Rate for Heart Failure No drug interventions Not Available Not Available withdrawn NCT05586828
A Single-center Retrospective Cohort Study to Explore the Prognostic Significance of CONUT in Elderly CAD Patients With HFpEFand Compare CONUT With Other Objective Nutritional Indices. No drug interventions Not Available Not Available completed NCT05122793
"HerzCheck" - Detection of Early Heart Failure Using Telemedicine in Structurally Weak Regions No drug interventions prevention Not Available active_not_recruiting NCT05887271
A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction No drug interventions treatment 2 / 3 recruiting NCT05888688
The Sarcopenia Study No drug interventions Not Available Not Available recruiting NCT05095688
Relationship Between Adipose Tissue Distribution and Arterial Stiffness in HFpEF No drug interventions Not Available Not Available unknown_status NCT06027307
Enavogliflozin Outcome Trial in Functional Tricuspid Regurgitation treatment 3 recruiting NCT06536309
Neprilysin Inhibition to Reduce Myocardial Fibrosis in Heart Failure With Preserved Ejection Fraction treatment 4 not_yet_recruiting NCT05114785
Heart Failure With Preserved Ejection Fraction: Evaluation and Recognition by CMR No drug interventions Not Available Not Available not_yet_recruiting NCT06409585
Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition No drug interventions Not Available Not Available recruiting NCT05556785
Association of Epicardial Adipose Tissue Volume Axnd Radiodensity With Coronary Artery Calcification in Patients With HFpEF No drug interventions Not Available Not Available unknown_status NCT03948685
Carvedilol SR Study for Biomarkers From Blood and Urine and Safety of in Patients With Heart Failure With Preserved Ejection Fraction treatment 4 unknown_status NCT05338437
NMES in HF Patients to Improve Functional Recovery Following Hospitalization No drug interventions supportive_care Not Available active_not_recruiting NCT03414632
Transthyretin Cardiac Amyloidosis in HFpEF No drug interventions diagnostic 0 completed NCT06379152
Effect of Bilirubin on Prognosis in Heart Failure With Preserved Ejection Fraction No drug interventions Not Available Not Available recruiting NCT06311552
Optimising CMR Scan Acquisitions for Novel Equipment/Sequences in Clinical Cardiovascular Populations. No drug interventions Not Available Not Available completed NCT05795400
Administration of the SGLT-2 Inhibitor Dapagliflozin in the Patients With Amyloid Cardiomyopathy treatment Not Available recruiting NCT06581159
Study of HS135 in Obese Patients with Pulmonary Hypertension and Heart Failure with Preserved Ejection Fraction No drug interventions treatment 1 not_yet_recruiting NCT05592275
A Study of LY3540378 in Participants With Worsening Chronic Heart Failure With Preserved Ejection Fraction (HFpEF) No drug interventions treatment 2 recruiting NCT05138575
SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial treatment 2 recruiting NCT04594499
The Relationship Between Pericardial Fat Thickness and Arterial Stiffness in HFpEF Patients No drug interventions Not Available Not Available unknown_status NCT01932606
Acute Effects of Inorganic Nitrite on Cardiovascular Hemodynamics in Heart Failure With Preserved Ejection Fraction treatment 2 completed NCT04281849
Balance, Aerobic Capacity, Mobility and Strength in Patients Hospitalized for Heart Failure (BAMS-HF) Program No drug interventions treatment Not Available completed NCT06061549
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection Fraction No drug interventions treatment 1 recruiting NCT04505449
Invasive Left Heart Catheterization Registry No drug interventions Not Available Not Available completed NCT06081049
The COLchicine HEART Failure PRESERVED Trial (COLHEART-PRESERVED) treatment 2 recruiting NCT04112849
Electronic S3 Prediction of Hospital Readmissions for HF Exacerbation No drug interventions Not Available Not Available completed NCT04153136
Effects of Sacubitril/Valsartan on Subclinical Heart Failure in HIV (The ENCHANTMENT HIV Study) treatment 2 recruiting NCT04111536
Developing Oral LT3 Therapy for Heart Failure - HFpEF treatment 1 / 2 completed NCT05126836
Cilostazol for HFpEF treatment 2 completed NCT05236413
The Effect of a High Fiber Diet and High-Intensity Interval Exercise in Patients With HFpEF No drug interventions supportive_care Not Available recruiting NCT05284617
Exploratory Ph 2A, Double-Blind, Placebo-Controlled Dose Escalation Study of Safety, Tolerability, PD, & PK of HU6 for Subjects With Obese HFpEF No drug interventions treatment 2 completed NCT05672134
Evaluation of GeranylGeranylAcetone in Heart Failure With Preserved Ejection Fraction treatment 2 enrolling_by_invitation NCT05068934
The Relationship Between Epicardial Fat Tissue and Cardiac Function in HFpEF Patients No drug interventions Not Available Not Available completed NCT05873634
HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets No drug interventions Not Available Not Available recruiting NCT06065124
Bariatric Surgery Evaluation and Assessment of Treatment Efficacy - Intervention Trial No drug interventions treatment Not Available not_yet_recruiting NCT04327596
Radiofrequency (RF) Ablation for Atrial Fibrillation (AF) in Patients With Heart Failure With Preserved Ejection Fraction No drug interventions treatment Not Available terminated NCT05992558
Longitudinal Multimarker Risk Models for Very Elderly Patients With Heart Failure and Preserved Ejection Fraction No drug interventions Not Available Not Available recruiting NCT05236335
Modulation of Circulating Levels of the Ketone Body 3-hydroxybutyrate in Patients With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction: Cardiovascular Effects. No drug interventions treatment Not Available completed NCT01411735
Evaluation of Enalapril Versus Placebo in Patients With Diastolic Heart Failure treatment 3 completed NCT05525663
Physical Rehabilitation for Older Patients With Acute Heart Failure With Preserved Ejection Fraction No drug interventions treatment Not Available recruiting NCT05562063
Sotagliflozin in Heart Failure With Preserved Ejection Fraction (HFpEF) Patients treatment 4 recruiting NCT05551663
Isometric Exercise Training in Participants With Heart Failure With Preserved Ejection Fraction No drug interventions prevention Not Available not_yet_recruiting NCT06196086
Myocardial Stiffness Evaluation in Patients With Heart Failure With Preserved Ejection Fraction No drug interventions Not Available Not Available recruiting NCT06517186
Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction No drug interventions Not Available Not Available recruiting NCT04233086
Retrospective Observational Analysis of a Cohort With Heart Failure With Preserved Ejection Fraction No drug interventions Not Available Not Available completed NCT04317339
The Efficacy and Safety of Zhigancao Tang Granule for HFpEF of Qi-Yin Dificiency No drug interventions treatment 2 unknown_status NCT05089539
The Effect of Angiotensin Receptor-Neprilysin Inhibition on Cardiac Fibrosis in Patients With HFpEF treatment 2 unknown_status NCT05129722
Polydiuretic Therapy for HFpEF, a Randomised Controlled Trial treatment 4 recruiting NCT06567925
Sleep Extension to Improve Sleep Efficiency and QoL in HF With Preserved Ejection Fraction: the SLEEP-HF Pilot Study No drug interventions treatment Not Available not_yet_recruiting NCT03923530
Pressure Assessment to Improve Outcomes After TAVR: a Registry treatment 0 completed NCT05839730
Fast Induced Remodeling in Heart Failure With Preserved Ejection Fraction No drug interventions treatment Not Available suspended NCT03617848
Optimising Management of Patients With Heart Failure With Preserved Ejection Fraction in Primary Care No drug interventions Not Available Not Available completed NCT04587648
Cardiac Amyloidosis in HFpEF No drug interventions Not Available Not Available recruiting NCT06388226
Leg Heat Therapy in Heart Failure With Preserved Ejection Fraction No drug interventions treatment Not Available recruiting NCT04065620
Ambulatory Blood Pressure in HFPEF Outcomes Global Registry No drug interventions Not Available Not Available unknown_status NCT00207220
Ventricular-Vascular Coupling in Heart Failure No drug interventions Not Available Not Available completed NCT06217120
Reversing Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction treatment 2 / 3 not_yet_recruiting NCT01047631
Role of Exercise in Diastolic Heart Failure No drug interventions treatment Not Available completed NCT04727073
Spironolactone In The Treatment of Heart Failure treatment 3 recruiting NCT03960073
Chronic Kidney Disease and Heart Failure With Preserved Ejection Fraction: The Role of Mitochondrial Dysfunction No drug interventions other Not Available completed NCT06479876
Home-Based Cardiac Rehabilitation for Patients With Heart Failure No drug interventions treatment Not Available recruiting NCT04632160
Extended IASD Investigation: REDUCE LAP-HF IV No drug interventions treatment Not Available withdrawn NCT04633460
Acute Effects of Exogenous Ketone Ester Administration in Heart Failure No drug interventions treatment 2 completed NCT04835194
Phenotypes and Outcomes of Heart Failure With Preserved Ejection Fraction in Patients With Hypertension and Diabetes No drug interventions Not Available Not Available completed NCT01030991
Classification of Heart Failure With Preserved Ejection Fraction No drug interventions Not Available Not Available completed NCT04113291
Randomized Controlled Pilot Trial of DASH Feeding in Older Low Socioeconomic Adults Without Heart Failure No drug interventions prevention Not Available withdrawn NCT04391491
Neuregulin-1 in Patient With Different Forms of Cardiovascular Diseases: a Pilot Study No drug interventions Not Available Not Available completed NCT04128891
Study of Sacubitril/ValsarTan on MyocardIal OxygenatioN and Fibrosis in Heart Failure With Preserved Ejection Fraction treatment 3 withdrawn NCT05055180
Right Ventricular Function and Pulmonary Hypertension in HFpEF No drug interventions Not Available Not Available unknown_status NCT04175080
Clinical Significance and Diagnosis of Sarcopenia in Cardiac Patients No drug interventions Not Available Not Available unknown_status NCT06442280
SGLT-2 Inhibitor and High-Dose Furosemide Plus Small-Volume Hypertonic Saline Solution in Acute HF treatment 4 not_yet_recruiting NCT04189029
PACIFIC-PRESERVED : PhenomApping, ClassIFication, and Innovation for Cardiac Dysfunction - HF With PRESERVED LVEF Study No drug interventions Not Available Not Available active_not_recruiting NCT04766892
A Study of Mavacamten in Participants With HFpEF and Elevation of NT-proBNP With or Without Elevation of cTnT treatment 2 completed NCT06278844
Exercise Capacity Improvement by Conduction System Pacing in heArt Failure patieNts Without Compelling CRT inDication No drug interventions treatment Not Available recruiting NCT01185067
Physiological Effects of Grape Seed Extract in Diastolic Heart Failure treatment 1 completed NCT01091467
Prospective Study of Heart Failure With Preserved Left Ventricular Ejection Fraction No drug interventions Not Available Not Available completed NCT06487468
Risk Factors In Heart Failure Patients With Preserved Ejection Fraction No drug interventions Not Available Not Available completed NCT05059769
Relationship Between Ambulatory Arterial Stiffness Index and Left Ventricular Diastolic Function in Patients With HFpEF No drug interventions Not Available Not Available unknown_status NCT05884346
Association Between Coronary and Peripheral Vascular Injury in Heart Failure Patients With Preserved Ejection Fraction. No drug interventions diagnostic Not Available not_yet_recruiting NCT04287946
Endovascular GSN Ablation in Subjects With HFpEF No drug interventions treatment Not Available enrolling_by_invitation NCT06337812
Fiber Supplementation in Heart Failure With Preserved Ejection Fraction (HFpEF) No drug interventions health_services_research Not Available recruiting NCT06391710
HRS9531 Injection in Obese Subjects With Heart Failure With Preserved Ejection Fraction No drug interventions treatment 2 recruiting NCT01618981
LEft Atrial Pacing in Diastolic Heart Failure No drug interventions Not Available Not Available completed NCT05985395
HEART Camp Connect: A Feasibility Study No drug interventions health_services_research Not Available completed NCT05719714
Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease treatment 1 / 2 recruiting NCT05824923
A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Failure No drug interventions treatment 3 recruiting NCT06174623
Feasibility Study to Support Cardiorenal Function in Acute Decompensated Heart Failure With Diuretic Resistance No drug interventions treatment Not Available not_yet_recruiting NCT05204238
Follow Up of acuTe Heart failUre: a pRospective Echocardiographic and Clinical Study (FUTURE) No drug interventions Not Available Not Available unknown_status NCT06401343
Use of SGLT2i in noHCM With HFpEF treatment 4 recruiting NCT03715543
Surgical Resection of the Greater Splanchnic Nerve in Subjects Having Heart Failure With Preserved Ejection Fraction No drug interventions treatment Not Available completed NCT05888233
Allopurinol Improves Heart Function in African Americans With Resistant Hypertension treatment 2 recruiting NCT06215586
Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Preserved Ejection Fraction (Cycle-2-PEF) treatment 2 recruiting NCT02435667
Resistance Training in HFpEF No drug interventions supportive_care Not Available completed NCT06057623
Neuromuscular Fatigue and Exercise Capacity in Patients With Type 2 Diabetes Mellitus and HFpEF No drug interventions Not Available Not Available recruiting NCT06467266
Mechanistic Insights From Temporary Pacing in HFpEF No drug interventions basic_science Not Available not_yet_recruiting NCT06338943
Middle-aged Women With Adverse Pregnancy Outcomes and Heart Failure With Preserved Ejection Fraction No drug interventions Not Available Not Available recruiting NCT05383287
Characteristics, Phenotypes, and TRAITS of Heart Failure With Preserved Ejection Fraction (TRAITS-HFpEF) No drug interventions Not Available Not Available recruiting NCT04232345
A Study to Assess the Effect AZD4831 in Japanese and Chinese Healthy Volunteers treatment 1 completed NCT05792059
DevElopMent of Clinical PATHwaYs to the Diagnosis of Heart Failure With Preserved Ejection Fraction No drug interventions Not Available Not Available recruiting NCT01989299
Ventricular Tachyarrhythmia Detection by Implantable Loop Recording in Patients With Heart Failure and Preserved Ejection Fraction No drug interventions Not Available Not Available completed NCT03988634
Changes in NT-proBNP, Safety, and Tolerability in HFpEF Patients With a WHF Event (HFpEF Decompensation) Who Have Been Stabilized and Initiated at the Time of or Within 30 Days Post-decompensation (PARAGLIDE-HF) treatment 3 completed NCT03877224
DETERMINE-preserved - Dapagliflozin Effect on Exercise Capacity Using a 6-minute Walk Test in Patients With Heart Failure With Preserved Ejection Fraction treatment 3 completed NCT04327024
Study of Verinurad in Heart Failure With Preserved Ejection Fraction treatment 2 completed NCT06036186
Study for the Treatment of Heart Failure With Preserved Ejection Fraction Associated With High Blood Pressure Using Right Atrial Pacing Controlled by the PressurePaceTM System No drug interventions treatment Not Available completed NCT05441839
UK Heart Failure With Preserved Ejection Fraction No drug interventions Not Available Not Available recruiting NCT04847557
A Study of Tirzepatide (LY3298176) in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) and Obesity: The SUMMIT Trial treatment 3 completed NCT06560762
Study in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) No drug interventions treatment 1 not_yet_recruiting NCT03909295
An Open-label Extension Study Evaluating Safety and Tolerability of LCZ696 in Subjects Who Completed PARAGON-HF in Japan. treatment 3 terminated NCT01714752
Evaluation of Left Ventricular Filling Pressures During Exercise No drug interventions diagnostic Not Available completed NCT04822649
Exercise Capacity According to Coronary Microvascular Dysfunction and Body Composition No drug interventions diagnostic Not Available recruiting NCT05371496
Cardiac and Metabolic Effects of Semaglutide in Heart Failure With Preserved Ejection Fraction treatment 2 recruiting NCT05136820
Flow Regulation by Opening the SepTum in Patients With Heart Failure; a Prospective, Randomized, Sham-controlled, Double-blind, Global Multicenter Study No drug interventions treatment Not Available active_not_recruiting NCT03843060
A Phase 1 Study to Assess the Pharmacokinetics of AZD9977 Administered Alone and in Combination With Itraconazole in Healthy Volunteers treatment 1 completed NCT03876223
Women's Ischemia Syndrome Evaluation (WISE) Pre-HFpEF No drug interventions Not Available Not Available recruiting