NCT05581927
Whole-Body Hypothermia for Neonates With Hypoxic-Ischemic Encephalopathy(HIE) No drug interventions treatment Not Available withdrawn NCT05767476
Neurodevelopmental Outcome in Newborn With Hypoxic-ischemic Encephalopathy Treated With Therapeutic Hypothermia No drug interventions Not Available Not Available recruiting NCT04728438
Effect of Targeted Temperature Management on Cerebral Autoregulation in Patients With Neurocritical Diseases No drug interventions Not Available Not Available unknown_status NCT02800018
Correlation of Risk Factors and Severity of Hypoxic-ischaemic Encephalopathy No drug interventions Not Available Not Available completed NCT01545271
Xenon and Cooling Therapy in Babies at High Risk of Brain Injury Following Poor Condition at Birth treatment 1 / 2 completed NCT00934700
Neuroprotective Effects of Hypothermia Combined With Inhaled Xenon Following Perinatal Asphyxia No drug interventions treatment Not Available completed NCT02700854
Hypoxic-Ischemic Encephalopathy Therapy Optimization in Neonates for Better Neuroprotection With Inhalative CO2 No drug interventions treatment 1 completed NCT02071394
Xenon and Cooling Therapy in Babies at High Risk of Brain Injury Following Poor Condition at Birth treatment 2 completed NCT01793129
Preemie Hypothermia for Neonatal Encephalopathy No drug interventions treatment Not Available completed NCT00614744
Late Hypothermia for Hypoxic-Ischemic Encephalopathy No drug interventions treatment Not Available completed NCT05820178
tDCS and rTMS in Patients With Early Disorders of Consciousness No drug interventions treatment Not Available not_yet_recruiting NCT02676063
Long Term Prognostic of Neonatal Hypoxic Ischemic Encephalopathy With Hypothermia Treatment No drug interventions Not Available Not Available unknown_status NCT01192776
Optimizing (Longer, Deeper) Cooling for Neonatal Hypoxic-Ischemic Encephalopathy(HIE) No drug interventions treatment Not Available terminated NCT02287077
Umbilical Cord Milking for Neonates With Hypoxic Ischemic Encephalopathy No drug interventions prevention Not Available completed NCT01683383
California Transport Cooling Trial No drug interventions treatment Not Available completed NCT00620711
Pilot Study of Head Cooling in Preterm Infants With Hypoxic Ischemic Encephalopathy No drug interventions treatment 1 completed NCT00624871
Ascorbic Acid and Ibuprofen in Infants With Hypoxic Ischemic Encephalopathy treatment Not Available completed NCT01481207
Magnetic Resonance Imaging and Spectroscopy Biomarkers of Neonatal Hypoxic Ischemic Encephalopathy No drug interventions Not Available Not Available completed NCT01471015
Darbe Administration in Newborns Undergoing Cooling for Encephalopathy treatment 1 / 2 completed NCT01649648
Autologous Cord Blood Cells for Brain Injury in Term Newborns treatment 1 completed NCT01128673
MRI Thermal Imaging of Infants Undergoing Cooling for Hypoxic Ischemic Encephalopathy(HIE) No drug interventions Not Available Not Available withdrawn NCT00945789
Erythropoietin in Infants With Hypoxic Ischemic Encephalopathy (HIE) treatment 1 / 2 completed NCT02621944
Melatonin as a Neuroprotective Therapy in Neonates With HIE Undergoing Hypothermia treatment 0 recruiting NCT02578823
Targeted Temperature Management After In-Hospital Cardiac Arrest No drug interventions treatment Not Available unknown_status NCT02551003
Neuroprotective Effect of Autologous Cord Blood Combined With Therapeutic Hypothermia Following Neonatal Encephalopathy treatment 1 / 2 withdrawn NCT01962233
Umbilical Cord Derived Mesenchymal Stem Cells Therapy in Hypoxic Ischemic Encephalopathy No drug interventions treatment 1 unknown_status NCT00097097
Neonatal Resuscitation in Zambia No drug interventions diagnostic 3 completed NCT03071783
Intra-operative Feed Back on Traction Force During Vacuum Extraction: Safe Vacuum Extraction Alliance No drug interventions prevention Not Available completed NCT06145256
Radiological Evaluation of Hypoxic Ischemic Encephalopathy No drug interventions Not Available Not Available not_yet_recruiting NCT02683915
Reno-protective Effect of Brain Cooling in Newborn With Hypoxia No drug interventions Not Available Not Available completed NCT01765218
Topiramate in Neonates Receiving Whole Body Cooling for Hypoxic Ischemic Encephalopathy treatment 1 / 2 terminated NCT01241019
Safety and Efficacy of Topiramate in Neonates With Hypoxic Ischemic Encephalopathy Treated With Hypothermia treatment 2 completed NCT02826941
Moderate Hypothermia in Neonatal Hypoxic Ischemic Encephalopathy No drug interventions treatment 2 completed NCT01138176
Whole Body Cooling Using Phase Changing Material No drug interventions treatment 1 / 2 unknown_status NCT02349672
Clinical Utility of Serum Biomarkers for the Management of Neonatal Hypoxic Ischemic Encephalopathy (Control Levels) No drug interventions Not Available Not Available completed NCT01732146
Efficacy of Erythropoietin to Improve Survival and Neurological Outcome in Hypoxic Ischemic Encephalopathy treatment 3 completed NCT00993564
Magnetic Resonance Imaging (MRI) Thermal Imaging of Infants Undergoing Cooling for Hypoxic Ischemic Encephalopathy (HIE) No drug interventions Not Available Not Available withdrawn NCT02605018
Neuroprotective Effect of Autologous Cord Blood Combined With Therapeutic Hypothermia Following Neonatal Encephalopathy treatment 1 / 2 not_yet_recruiting NCT03162653
Effect of Allopurinol for Hypoxic-ischemic Brain Injury on Neurocognitive Outcome treatment 3 recruiting NCT06370624
PEDI-REAVASC Resonance Imaging of Infants With Hypoxic Ischemic Encephalopathy After Hypothermia Treatment. No drug interventions diagnostic Not Available active_not_recruiting NCT01862250
Safety of Clonidine in Infants With Hypoxic Ischemic Encephalopathy During Therapeutic Hypothermia treatment 1 / 2 completed NCT05130528
Therapeutic Intervention Supporting Development From NICU to 6 Months for Infants Post Hypoxic-Ischemic Encephalopathy No drug interventions other Not Available completed NCT05568264
Effects of a Physical Therapy Intervention on Motor Delay in Infants Admitted to a Neonatal Intensive Care Unit No drug interventions treatment Not Available recruiting NCT03913221
Caffeine for Hypoxic-Ischemic Encephalopathy treatment 1 active_not_recruiting NCT03079284
Holding, Stress, and Bonding During Therapeutic Hypothermia No drug interventions other Not Available completed NCT02854579
Neural Progenitor Cell and Paracrine Factors to Treat Hypoxic Ischemic Encephalopathy No drug interventions treatment Not Available unknown_status NCT06195345
Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1) No drug interventions Not Available Not Available recruiting NCT04337697
Neonatal Seizure Registry - Developmental Functional EValuation No drug interventions Not Available Not Available active_not_recruiting NCT01059461
Study of Cerebrolysin for Treatment of Infants With History of Neonatal Hypoxic Ischemic Encephalopathy prevention 2 completed NCT02700828
Hydrocortisone Treatment In Systemic Low Blood Pressure During Hypothermia in Asphyxiated Newborns treatment 2 / 3 completed NCT05778188
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia No drug interventions treatment 2 recruiting NCT04506788
EEG Slow Wave Activity in Hypoxic Brain Injury No drug interventions Not Available Not Available completed NCT06429007
A Safety and Feasibility Trial Protocol of Metformin in Infants After Perinatal Brain Injury treatment 2 not_yet_recruiting NCT05495607
Continous Renal Replacement Therapy With the CARPEDIEM® in a French National Cohort of 25 Neonates and Small Infants No drug interventions Not Available Not Available completed NCT06427642
Efficacy Evaluation of UCB-MNCs in the Treatment of Refractory Neonatal Diseases No drug interventions treatment Not Available recruiting NCT02544542
Clinical Trial of a New Rectum Cooling System on Patients of Hypoxic-ischemic Brain Damage No drug interventions treatment Not Available completed NCT05787899
Hypothermia's Effect on Hepatitis B Vaccination No drug interventions Not Available Not Available recruiting NCT02256618
Autologous Cord Blood Cell Therapy for Neonatal Encephalopathy No drug interventions treatment 1 completed NCT05379218
RIC in HIE: A Safety and Feasibility Trial No drug interventions other Not Available completed NCT04766541
THE ROLE OF CARDIAC MARKERS IN HYPOXIC ISCHEMIC ENCEPHALOPATHY IN LONG-TERM NEURODEVELOPMENTAL FOLLOW UP No drug interventions Not Available Not Available unknown_status NCT04602325
Systemic Biomarkers of Brain Injury From Hyperammonemia No drug interventions Not Available Not Available recruiting NCT03534466
Evaluation of Long-Term Gait Development in Infants With Neonatal Encephalopathy Using Infant Treadmill No drug interventions prevention Not Available terminated NCT05514665
Functional Imaging of Baby Brains No drug interventions Not Available Not Available not_yet_recruiting NCT03657394
Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries No drug interventions prevention Not Available recruiting NCT06460480
Monitoring After Cardiac Arrest: Electroencephalogram and Cerebral Oximetry in Predicting Outcome No drug interventions Not Available Not Available recruiting NCT06448780
Dose Optimization of Caffeine for HIE treatment 1 recruiting NCT03079492
MRI of Neonate With HIE Before and During the Moderate Hypothermia No drug interventions Not Available Not Available unknown_status NCT01936246
Protein Supplementation in Infants With Brain Injury No drug interventions prevention Not Available completed NCT03181646
Role of Citicoline in Treatment of Newborns With Hypoxic Ischemic Encephalopathy treatment 3 unknown_status NCT03681314
Umbilical Cord Milking in Neonates Who Are Depressed at Birth-Developmental Follow Up (MIDAB-FU) No drug interventions supportive_care Not Available withdrawn NCT02264808
Developmental Outcomes No drug interventions Not Available Not Available completed NCT05687708
Effect of Non-nutritive Sucking on Transition to Oral Feeding in Infants With Asphyxia No drug interventions treatment Not Available completed NCT03246243
Quantitative Assessment of Sucking for Early Diagnosis of Brain Injury in Infants at High Risk No drug interventions Not Available Not Available terminated NCT03024021
Cerebral Oxymetry and Neurological Outcome in Therapeutic Hypothermia No drug interventions Not Available Not Available completed NCT02529202
Dexmedetomidine Pharmacokinetics in Neonates During Therapeutic Hypothermia treatment 0 completed NCT05295784
PK and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia treatment 1 withdrawn NCT03179553
Heart Beat Variability in Neonatal Encephalopathy No drug interventions Not Available Not Available active_not_recruiting NCT03527498
Evaluation of Long-term Neurodevelopment in Neonatal Encephalopathy by Infant Treadmill No drug interventions prevention Not Available withdrawn NCT03786497
Protecting Brains and Saving Futures - the PBSF Protocol No drug interventions Not Available Not Available unknown_status NCT02260271
Florida Neonatal Neurologic Network No drug interventions Not Available Not Available enrolling_by_invitation NCT05901688
Umbilical Cord Abnormalities in the Prediction of Adverse Pregnancy Outcomes No drug interventions Not Available Not Available recruiting NCT00719407
Neonatal Erythropoietin in Asphyxiated Term Newborns treatment 1 completed NCT00890409
Safety and Efficacy of Hypothermia to Treat Neonatal Hypoxic-Ischemic Encephalopathy No drug interventions treatment 3 completed NCT05610085
A Dose Escalation Study of Levetiracetam in the Treatment of Neonatal Seizures treatment 2 recruiting NCT05520359
Spinal Stimulation and Mobility Devices No drug interventions basic_science Not Available recruiting NCT05361070
Neonatal Seizure Registry, GEnetics of Post-Neonatal Epilepsy No drug interventions Not Available Not Available recruiting NCT03682042
Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries Developmental Follow Up No drug interventions prevention Not Available recruiting NCT04445649
Prognostic Factors to Regain Consciousness No drug interventions Not Available Not Available recruiting NCT03837717
The Impact of Holding on Stress and Bonding in Mother-Infant Pairs During Therapeutic Hypothermia No drug interventions supportive_care Not Available completed NCT03996317
Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing Abnormalities No drug interventions treatment Not Available withdrawn NCT04913324
Early Virtual Intervention for Infants With CP Following HIE Diagnosis No drug interventions supportive_care Not Available not_yet_recruiting NCT03806816
Use of Melatonin for Neuroprotection in Asphyxiated Newborns No drug interventions treatment Not Available unknown_status NCT01747863
Prospective Research in Infants With Mild Encephalopathy No drug interventions Not Available Not Available completed NCT06344286
The Effects of Minimal Enteral Nutrition on Mesenteric Blood Flow and Oxygenation in Neonates With HIE No drug interventions supportive_care Not Available completed NCT04772222
Dexmedetomidine Use in Infants Undergoing Cooling Due to Neonatal Encephalopathy (DICE Trial) treatment 2 recruiting NCT02894866
Hyperbaric Oxygen Therapy Improves Outcome of Hypoxic-Ischemic Encephalopathy No drug interventions treatment Not Available unknown_status NCT03549520
CEUS Evaluation of Hypoxic Ischemic Injury diagnostic 3 completed NCT05986994
Identification of a Pool of miRNA to Improve Early Management of Perinatal Asphyxia and Hypoxic Ischemic Encephalopathy No drug interventions Not Available Not Available recruiting NCT03640494
Bedside Optical Retinal Assessment of Hypoxic Ischemic Encephalopathy in Infants No drug interventions Not Available Not Available completed NCT03163589
Erythropoietin in Management of Neonatal Hypoxic Ischemic Encephalopathy treatment 3 unknown_status NCT01913340
Neonatal Erythropoietin And Therapeutic Hypothermia Outcomes in Newborn Brain Injury (NEATO) treatment 1 / 2 completed NCT05514340
Assess Safety and Efficacy of Sovateltide in Hypoxic-ischemic Encephalopathy No drug interventions treatment 2 recruiting NCT03079167
PAEAN - Erythropoietin for Hypoxic Ischaemic Encephalopathy in Newborns treatment 3 completed NCT00817401
Systemic Hypothermia Improves Outcome of Hypoxic-Ischemic Encephalopathy No drug interventions prevention 1 / 2 completed NCT00808704
Neurological Outcome After Erythropoietin Treatment for Neonatal Encephalopathy prevention 1 / 2 completed NCT06090968
Umbilical Cord Milking Versus Immediate Cord Clamping in Full Term Neonates (≥ 37 Weeks) Requiring Resuscitation No drug interventions prevention Not Available completed NCT05971446
Healthy Little Eyes No drug interventions Not Available Not Available recruiting NCT03352310
Feasibility and Safety of Umbilical Cord Blood Transfusion in the Treatment of Neonatal Cerebral Ischemia and Anemia treatment 1 unknown_status NCT05836610
Hydrocortisone Therapy Optimization During Hypothermia Treatment in Asphyxiated Neonates treatment 4 recruiting NCT03485781
Propofol-induced EEG Changes in Hypoxic Brain Injury No drug interventions Not Available Not Available completed NCT03123081
Role of Umbilical Cord Milking in the Management of Hypoxic-ischemic Encephalopathy in Neonates No drug interventions prevention Not Available unknown_status NCT05048550
Babies in Glasses; a Feasibility Study. No drug interventions other Not Available unknown_status NCT02252848
Phase I Clinical Trial to Determine the Safety of Clonidine in Infants With HIE During Therapeutic Hypothermia. treatment 1 recruiting NCT02019147
BiHiVE2 Study. The Investigation and Validation of Predictive Biomarkers in Hypoxic-ischaemic Encephalopathy. No drug interventions Not Available Not Available completed