Diphenoxylate Completed Phase 2 Trials for Stage III Breast Cancer AJCC V7 / Stage IIIC Breast Cancer AJCC v7 / Stage II Breast Cancer AJCC v6 and v7 / Stage IIA Breast Cancer AJCC v6 and v7 / HER2/Neu-positive Breast Cancer / Stage IIIB Breast Cancer AJCC v7 / Breast Adenocarcinoma / Stage IIB Breast Cancer AJCC v6 and v7 / Stage IIIA Breast Cancer AJCC v7 Treatment

Indications	Status	Purpose	Phase
DBCOND0037625 (Stage III Breast Cancer AJCC V7) DBCOND0092288 (Stage IIIC Breast Cancer AJCC v7) DBCOND0092283 (Stage II Breast Cancer AJCC v6 and v7) DBCOND0092284 (Stage IIA Breast Cancer AJCC v6 and v7) DBCOND0037730 (HER2/Neu-positive Breast Cancer) DBCOND0092287 (Stage IIIB Breast Cancer AJCC v7) DBCOND0029215 (Breast Adenocarcinoma) DBCOND0092285 (Stage IIB Breast Cancer AJCC v6 and v7) DBCOND0092286 (Stage IIIA Breast Cancer AJCC v7)	Completed	Treatment	2

clinicaltrials.gov Identifier	Title	Drugs
NCT03094052	Incidence and Severity of Diarrhea in Patients With Stage II-IIIC HER2 Positive Breast Cancer Treated With Trastuzumab and Neratinib	Atropine (DB00572) Diphenoxylate (DB01081) Loperamide (DB00836) Neratinib (DB11828) Trastuzumab (DB00072)