CoviGlobulin
Identification
- Generic Name
- CoviGlobulin
- DrugBank Accession Number
- DB15747
- Background
CoviGlobulin, a rabbit polyclonal antibody, was specifically designed as a potential therapy for COVID-19. Rabbit polyclonal antibodies are derived from the rabbit, a common animal host for polyclonal production. The antibodies themselves are produced in response to an immunogen and derived from antibody-producing plasma cells that were once B-cell clones. Different antibodies have different mechanisms of action depending on their target. Current applications of antibodies include, but are not limited to, targeting cancer, inflammatory diseases, organ transplantation, cardiovascular disease, infection, respiratory disease, and ophthalmologic disease.
- Type
- Biotech
- Groups
- Investigational
- Biologic Classification
- Protein Based Therapies
Blood factors - Protein Chemical Formula
- Not Available
- Protein Average Weight
- Not Available
- Sequences
- Not Available
- Synonyms
- Not Available
- External IDs
- CoviGlobulin
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
No information available thus far on the MoA for CoviGlobulin.
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Chemical TaxonomyProvided by Classyfire
- Description
- Not Available
- Kingdom
- Organic Compounds
- Super Class
- Organic Acids
- Class
- Carboxylic Acids and Derivatives
- Sub Class
- Amino Acids, Peptides, and Analogues
- Direct Parent
- Peptides
- Alternative Parents
- Not Available
- Substituents
- Not Available
- Molecular Framework
- Not Available
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- Not Available
- CAS number
- Not Available
References
- General References
- Nakazawa M, Mukumoto M, Miyatake K: Production and purification of polyclonal antibodies. Methods Mol Biol. 2010;657:63-74. doi: 10.1007/978-1-60761-783-9_5. [Article]
- Suzuki M, Kato C, Kato A: Therapeutic antibodies: their mechanisms of action and the pathological findings they induce in toxicity studies. J Toxicol Pathol. 2015 Jul;28(3):133-9. doi: 10.1293/tox.2015-0031. Epub 2015 Jun 15. [Article]
- Stuart J. Knechtle, Peter J Morris (2013). Kidney Transplantation - Principles and Practice. Elsevier Health Sciences. [ISBN:9781455774050]
- Labome: Rabbit Antibody [Link]
- External Links
- Not Available
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at August 11, 2020 21:43 / Updated at August 13, 2020 07:02