Flurbiprofen sodiumProduct ingredient for Flurbiprofen
- Name
- Flurbiprofen sodium
- Drug Entry
- Flurbiprofen
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis. Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen.
- Accession Number
- DBSALT000544
- Structure
Structure for Flurbiprofen sodium (DBSALT000544)
- Synonyms
- Not Available
- UNII
- M3QE6AS001
- CAS Number
- Not Available
- Weight
- Average: 266.2428
Monoisotopic: 266.071902508 - Chemical Formula
- C15H12FNaO2
- InChI Key
- AUAGTGKMTMVIKN-UHFFFAOYSA-M
- InChI
- InChI=1S/C15H13FO2.Na/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11;/h2-10H,1H3,(H,17,18);/q;+1/p-1
- IUPAC Name
- sodium 2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoate
- SMILES
- [Na+].CC(C([O-])=O)C1=CC(F)=C(C=C1)C1=CC=CC=C1
- External Links
- PubChem Compound
- 23684814
- ChemSpider
- 38291
- ChEBI
- 774941
- ChEMBL
- CHEMBL1200990
- Wikipedia
- Flurbiprofen
- Predicted Properties
Property Value Source Water Solubility 0.013 mg/mL ALOGPS logP 4.07 ALOGPS logP 3.94 Chemaxon logS -4.3 ALOGPS pKa (Strongest Acidic) 4.42 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 40.13 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 78.13 m3·mol-1 Chemaxon Polarizability 24.84 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon