Lomefloxacin hydrochlorideProduct ingredient for Lomefloxacin
- Name
- Lomefloxacin hydrochloride
- Drug Entry
- Lomefloxacin
Lomefloxacin is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and urinary tract infections (UTIs). Additionally, it has been employed for the prophylaxis of UTIs prior to surgery as well.
- Accession Number
- DBSALT000795
- Structure
- Synonyms
- Lomefloxacin HCl
- UNII
- 9VC7S3ZXXB
- CAS Number
- 98079-52-8
- Weight
- Average: 387.809
Monoisotopic: 387.116125638 - Chemical Formula
- C17H20ClF2N3O3
- InChI Key
- KXEBLAPZMOQCKO-UHFFFAOYSA-N
- InChI
- InChI=1S/C17H19F2N3O3.ClH/c1-3-21-8-11(17(24)25)16(23)10-6-12(18)15(13(19)14(10)21)22-5-4-20-9(2)7-22;/h6,8-9,20H,3-5,7H2,1-2H3,(H,24,25);1H
- IUPAC Name
- 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
- SMILES
- Cl.CCN1C=C(C(O)=O)C(=O)C2=CC(F)=C(N3CCNC(C)C3)C(F)=C12
- External Links
- KEGG Compound
- C08053
- PubChem Compound
- 68624
- ChemSpider
- 61883
- ChEBI
- 6518
- ChEMBL
- CHEMBL1728
- Wikipedia
- Lomefloxacin
- Predicted Properties
Property Value Source Water Solubility 0.106 mg/mL ALOGPS logP 0 ALOGPS logP -0.43 Chemaxon logS -3.5 ALOGPS pKa (Strongest Acidic) 5.45 Chemaxon pKa (Strongest Basic) 8.78 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 72.88 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 90.11 m3·mol-1 Chemaxon Polarizability 34.56 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon