Trimipramine maleateProduct ingredient for Trimipramine
- Name
- Trimipramine maleate
- Drug Entry
- Trimipramine
Tricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
- Accession Number
- DBSALT000969
- Structure
Structure for Trimipramine maleate (DBSALT000969)
- Synonyms
- Not Available
- UNII
- 269K6498LD
- CAS Number
- 521-78-8
- Weight
- Average: 410.514
Monoisotopic: 410.220557454 - Chemical Formula
- C24H30N2O4
- InChI Key
- YDGHCKHAXOUQOS-BTJKTKAUSA-N
- InChI
- InChI=1S/C20H26N2.C4H4O4/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22;5-3(6)1-2-4(7)8/h4-11,16H,12-15H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
- IUPAC Name
- (2Z)-but-2-enedioic acid; (3-{2-azatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}-2-methylpropyl)dimethylamine
- SMILES
- [H]\C(=C(/[H])C(O)=O)C(O)=O.CC(CN(C)C)CN1C2=CC=CC=C2CCC2=CC=CC=C12
- External Links
- KEGG Compound
- C14029
- ChemSpider
- 4445487
- ChEBI
- 35030
- ChEMBL
- CHEMBL1200948
- Wikipedia
- Trimipramine
- Predicted Properties
Property Value Source Water Solubility 0.026 mg/mL ALOGPS logP 4.67 ALOGPS logP 4.76 Chemaxon logS -4 ALOGPS pKa (Strongest Basic) 9.42 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 6.48 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 95.02 m3·mol-1 Chemaxon Polarizability 35.32 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule Yes Chemaxon