Tiapride hydrochlorideProduct ingredient for Tiapride
- Name
- Tiapride hydrochloride
- Drug Entry
- Tiapride
Tiapride is a selective D2 and D3 dopamine receptor blocker in the brain.
- Accession Number
- DBSALT002373
- Structure
Structure for Tiapride hydrochloride (DBSALT002373)
- Synonyms
- Tiapride HCl
- UNII
- 25N106WEDO
- CAS Number
- 51012-33-0
- Weight
- Average: 364.89
Monoisotopic: 364.1223562 - Chemical Formula
- C15H25ClN2O4S
- InChI Key
- OTFDPNXIVHBTKW-UHFFFAOYSA-N
- InChI
- InChI=1S/C15H24N2O4S.ClH/c1-5-17(6-2)10-9-16-15(18)13-11-12(22(4,19)20)7-8-14(13)21-3;/h7-8,11H,5-6,9-10H2,1-4H3,(H,16,18);1H
- IUPAC Name
- N-[2-(diethylamino)ethyl]-5-methanesulfonyl-2-methoxybenzamide hydrochloride
- SMILES
- Cl.CCN(CC)CCNC(=O)C1=CC(=CC=C1OC)S(C)(=O)=O
- External Links
- ChemSpider
- 36445
- ChEBI
- 32220
- ChEMBL
- CHEMBL1256772
- Predicted Properties
Property Value Source Water Solubility 0.252 mg/mL ALOGPS logP 1.14 ALOGPS logP 0.46 Chemaxon logS -3.1 ALOGPS pKa (Strongest Acidic) 13.23 Chemaxon pKa (Strongest Basic) 8.87 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 75.71 Å2 Chemaxon Rotatable Bond Count 8 Chemaxon Refractivity 88.02 m3·mol-1 Chemaxon Polarizability 35.58 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon