Plague

Also known as: Plague, unspecified / Unspecified plague / Plague (disorder) / Yersinia pestis infection / Bubonic plague / Bubonic plague (disorder)

Drug	Drug Name	Drug Description
DB00618	Demeclocycline	A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections.
DB01017	Minocycline	A tetracycline analog used to treat a wide variety of infections in the body.
DB00218	Moxifloxacin	A fluoroquinolone antibiotic used to treat various bacterial infections.
DB01082	Streptomycin	An aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections.
DB00759	Tetracycline	An antibiotic used to treat a wide variety of susceptible infections.

Drug	Drug Name	Target	Type
DB00618	Demeclocycline	30S ribosomal protein	target
DB00618	Demeclocycline	Vasopressin V2 receptor	target
DB01017	Minocycline	30S ribosomal protein S4	target
DB01017	Minocycline	30S ribosomal protein S9	target
DB01017	Minocycline	16S ribosomal RNA	target
DB01017	Minocycline	Interleukin-1 beta	target
DB01017	Minocycline	Arachidonate 5-lipoxygenase	target
DB01017	Minocycline	Matrix metalloproteinase-9	target
DB01017	Minocycline	Vascular endothelial growth factor A	target
DB01017	Minocycline	Caspase-1	target
DB01017	Minocycline	Caspase-3	target
DB01017	Minocycline	Cytochrome c	target
DB01017	Minocycline	Solute carrier family 22 member 6	transporter
DB01017	Minocycline	Solute carrier family 22 member 7	transporter
DB01017	Minocycline	Outer membrane protein F	transporter
DB01017	Minocycline	Outer membrane porin C	transporter
DB01017	Minocycline	Mitogen-activated Protein Kinases	target
DB01017	Minocycline	Nitric oxide synthase, inducible	target
DB00218	Moxifloxacin	DNA gyrase subunit A	target
DB00218	Moxifloxacin	DNA topoisomerase 4 subunit A	target
DB00218	Moxifloxacin	DNA topoisomerase 2-alpha	target
DB00218	Moxifloxacin	Cytochrome P450 1A2	enzyme
DB00218	Moxifloxacin	Serum paraoxonase/arylesterase 1	target
DB01082	Streptomycin	30S ribosomal protein S12	target
DB01082	Streptomycin	16S ribosomal RNA	target
DB01082	Streptomycin	Protein-arginine deiminase type-4	target
DB01082	Streptomycin	23S ribosomal RNA	target
DB01082	Streptomycin	Bacterial outer membrane	target
DB01082	Streptomycin	Cytoplasmic membrane	target
DB00759	Tetracycline	16S ribosomal RNA	target
DB00759	Tetracycline	Major prion protein	target
DB00759	Tetracycline	Serum albumin	carrier
DB00759	Tetracycline	Cytochrome P450 3A4	enzyme
DB00759	Tetracycline	Solute carrier family 22 member 6	transporter
DB00759	Tetracycline	Solute carrier family 22 member 8	transporter
DB00759	Tetracycline	Solute carrier family 22 member 11	transporter
DB00759	Tetracycline	Solute carrier family 22 member 7	transporter
DB00759	Tetracycline	30S ribosomal protein S3	target
DB00759	Tetracycline	30S ribosomal protein S8	target
DB00759	Tetracycline	30S ribosomal protein S19	target
DB00759	Tetracycline	30S ribosomal protein S14	target
DB00759	Tetracycline	30S ribosomal protein S7	target
DB00759	Tetracycline	Multidrug translocase MdfA	target
DB00759	Tetracycline	Protein-arginine deiminase type-4	target
DB00759	Tetracycline	Solute carrier organic anion transporter family member 2B1	transporter

Drug	Drug Name	Phase	Status	Count
DB00537	Ciprofloxacin	2	Unknown Status	1
DB00254	Doxycycline	2	Unknown Status	1
DB05463	ISS-1018	2	Active Not Recruiting	1
DB15461	Yersinia pestis 195/p antigen (formaldehyde inactivated)	2	Active Not Recruiting	1
DB15461	Yersinia pestis 195/p antigen (formaldehyde inactivated)	2	Completed	1
DB00798	Gentamicin	2 / 3	Completed	1
DB01082	Streptomycin	2 / 3	Completed	1