Eosinophilic Esophagitis

Also known as: Eosinophilic Esophagitis (EoE) / Oesophagitis, Eosinophilic / Eosinophilic oesophagitis / Eosinophilic esophagitis (disorder)

Drug	Drug Name	Drug Description
DB01222	Budesonide	A corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
DB12159	Dupilumab	A monoclonal antibody used to treat moderate to severe atopic dermatitis, asthma, and nasal polyps accompanied by chronic rhinosinusitis in adolescents and adults.
DB00588	Fluticasone propionate	A glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis.

Drug	Drug Name	Target	Type
DB01222	Budesonide	Glucocorticoid receptor	target
DB01222	Budesonide	Cytochrome P450 3A4	enzyme
DB01222	Budesonide	Cytochrome P450 3A5	enzyme
DB01222	Budesonide	Bile salt export pump	transporter
DB01222	Budesonide	P-glycoprotein 1	transporter
DB01222	Budesonide	Annexin A1	target
DB01222	Budesonide	Cytochrome P450 3A Subfamily	enzyme
DB01222	Budesonide	Cytochrome P450 2A6	enzyme
DB01222	Budesonide	Cytochrome P450 1B1	enzyme
DB01222	Budesonide	Cytochrome P450 2B6	enzyme
DB01222	Budesonide	Cytochrome P450 2C8	enzyme
DB01222	Budesonide	Cytochrome P450 2C9	enzyme
DB01222	Budesonide	Cytochrome P450 2C19	enzyme
DB01222	Budesonide	Corticosteroid-binding globulin	carrier
DB01222	Budesonide	Solute carrier organic anion transporter family member 1A2	transporter
DB01222	Budesonide	Solute carrier family 22 member 8	transporter
DB01222	Budesonide	Serum albumin	carrier
DB12159	Dupilumab	Interleukin-4 receptor subunit alpha	target
DB12159	Dupilumab	Interleukin-13	target
DB12159	Dupilumab	Interleukin-4	target
DB00588	Fluticasone propionate	Corticosteroid-binding globulin	carrier
DB00588	Fluticasone propionate	Cytosolic phospholipase A2	target
DB00588	Fluticasone propionate	Glucocorticoid receptor	target
DB00588	Fluticasone propionate	Cytochrome P450 3A4	enzyme
DB00588	Fluticasone propionate	Progesterone receptor	target
DB00588	Fluticasone propionate	Mineralocorticoid receptor	target
DB00588	Fluticasone propionate	Cytochrome P450 3A5	enzyme
DB00588	Fluticasone propionate	Cytochrome P450 3A7	enzyme
DB00588	Fluticasone propionate	Cytochrome P450 2C8	enzyme
DB00588	Fluticasone propionate	Solute carrier organic anion transporter family member 1B1	carrier
DB00588	Fluticasone propionate	P-glycoprotein 1	transporter
DB00588	Fluticasone propionate	Solute carrier organic anion transporter family member 1B1	transporter

Drug	Drug Name	Phase	Status	Count
DB01109	Heparin	0	Completed	1
DB00364	Sucralfate	0	Completed	1
DB14227	Technetium Tc-99m	0	Completed	1
DB00394	Beclomethasone dipropionate	1	Completed	1
DB18378	CALY-002	1	Recruiting	1
DB18427	Cendakimab	1	Recruiting	1
DB00471	Montelukast	1	Completed	1
DB00043	Omalizumab	1	Completed	1
DB00877	Sirolimus	1	Terminated	1
DB05351	Dexlansoprazole	1 / 2	Withdrawn	1
DB06612	Mepolizumab	1 / 2	Completed	1
DB00058	Alpha-1-proteinase inhibitor	2	Recruiting	1
DB11842	Angiotensin II	2	Completed	1
DB11105	Benzalkonium	2	Recruiting	1
DB01019	Bethanechol	2	Terminated	1
DB01222	Budesonide	2	Completed	5
DB01222	Budesonide	2	Not Yet Recruiting	1
DB01222	Budesonide	2	Terminated	1
DB14789	Dectrekumab	2	Completed	1
DB12159	Dupilumab	2	Completed	1
DB14766	Etrasimod	2	Completed	1
DB00927	Famotidine	2	Terminated	1
DB08906	Fluticasone furoate	2	Completed	1
DB00588	Fluticasone propionate	2	Completed	3
DB00448	Lansoprazole	2	Completed	1
DB00455	Loratadine	2	Terminated	1
DB00678	Losartan	2	Completed	2
DB06612	Mepolizumab	2	Completed	3
DB00244	Mesalazine	2	Completed	1
DB14512	Mometasone furoate	2	Recruiting	1
DB14512	Mometasone furoate	2	Terminated	1
DB11900	OC-459	2	Completed	1
DB01222	Budesonide	2 / 3	Completed	1
DB00736	Esomeprazole	2 / 3	Completed	1
DB00588	Fluticasone propionate	2 / 3	Completed	2
DB16728	Lirentelimab	2 / 3	Completed	1
DB06602	Reslizumab	2 / 3	Completed	1
DB12023	Benralizumab	3	Terminated	1
DB01222	Budesonide	3	Completed	4
DB01222	Budesonide	3	Terminated	1
DB18427	Cendakimab	3	Recruiting	1
DB12159	Dupilumab	3	Active Not Recruiting	1
DB12159	Dupilumab	3	Completed	1
DB00588	Fluticasone propionate	3	Completed	3
DB00588	Fluticasone propionate	3	Withdrawn	1
DB00471	Montelukast	3	Withdrawn	1
DB06602	Reslizumab	3	Completed	1
DB15090	Tezepelumab	3	Recruiting	1
DB01222	Budesonide	4	Completed	2
DB01222	Budesonide	4	Recruiting	1
DB01003	Cromoglicic acid	4	Completed	1
DB12159	Dupilumab	4	Recruiting	1
DB13867	Fluticasone	4	Completed	1
DB13867	Fluticasone	4	Unknown Status	1
DB00588	Fluticasone propionate	4	Completed	1
DB00588	Fluticasone propionate	4	Recruiting	1
DB00448	Lansoprazole	4	Terminated	1
DB00338	Omeprazole	4	Recruiting	1
DB00338	Omeprazole	4	Unknown Status	1
DB15049	Sucralose	4	Completed	1
DB01222	Budesonide	Not Available	Completed	1
DB01222	Budesonide	Not Available	Not Yet Recruiting	1
DB00736	Esomeprazole	Not Available	Completed	1
DB13867	Fluticasone	Not Available	Completed	1
DB13867	Fluticasone	Not Available	Unknown Status	1
DB00588	Fluticasone propionate	Not Available	Available	1
DB00471	Montelukast	Not Available	Terminated	1
DB00338	Omeprazole	Not Available	Active Not Recruiting	1
DB00904	Ondansetron	Not Available	Completed	1
DB00818	Propofol	Not Available	Completed	1
DB01236	Sevoflurane	Not Available	Completed	1