Graves Ophthalmopathy

Also known as: Graves' Ophthalmopathy / Endocrine ophthalmopathy / Thyroid-Related Eye Disease / Graves' Ophthalmopathy (GO) / Thyroid Eye Disease / Thyroid Related Eye Disease / Thyroid eye disease (disorder) / Endocrine exophthalmos / Exophthalmos endocrine

Drug	Drug Name	Drug Description
DB00635	Prednisone	A corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
DB06343	Teprotumumab	A fully human monoclonal antibody directed against insulin-like growth factor-1 receptor for the treatment of thyroid eye disease.

Drug	Drug Name	Target	Type
DB00635	Prednisone	Glucocorticoid receptor	target
DB00635	Prednisone	Cytochrome P450 3A4	enzyme
DB00635	Prednisone	P-glycoprotein 1	transporter
DB00635	Prednisone	Solute carrier organic anion transporter family member 1A2	transporter
DB00635	Prednisone	Cytochrome P450 2C19	enzyme
DB00635	Prednisone	Serum albumin	carrier
DB00635	Prednisone	Cytochrome P450 3A5	enzyme
DB00635	Prednisone	Corticosteroid-binding globulin	carrier
DB00635	Prednisone	Cytochrome P450 3A Subfamily	enzyme
DB00635	Prednisone	Cytochrome P450 2A6	enzyme
DB00635	Prednisone	Cytochrome P450 1B1	enzyme
DB00635	Prednisone	Cytochrome P450 2B6	enzyme
DB00635	Prednisone	Cytochrome P450 2C8	enzyme
DB00635	Prednisone	Cytochrome P450 2C9	enzyme
DB00635	Prednisone	Corticosteroid 11-beta-dehydrogenase isozyme 1	enzyme
DB06343	Teprotumumab	Insulin-like growth factor 1 receptor	target

Drug	Drug Name	Phase	Status	Count
DB00905	Bimatoprost	0	Recruiting	1
DB00959	Methylprednisolone	0	Not Yet Recruiting	1
DB00877	Sirolimus	0	Not Yet Recruiting	1
DB00207	Azithromycin	1 / 2	Withdrawn	1
DB00254	Doxycycline	1 / 2	Completed	1
DB08885	Aflibercept	2	Recruiting	1
DB00482	Celecoxib	2	Terminated	1
DB00254	Doxycycline	2	Recruiting	1
DB14740	Hyaluronidase	2	Recruiting	1
DB00959	Methylprednisolone	2	Recruiting	1
DB00959	Methylprednisolone	2	Terminated	1
DB05496	Otelixizumab	2	Terminated	1
DB00877	Sirolimus	2	Not Yet Recruiting	1
DB06273	Tocilizumab	2	Recruiting	1
DB06075	Linsitinib	2 / 3	Recruiting	2
DB00959	Methylprednisolone	2 / 3	Withdrawn	1
DB09100	Thyroid, porcine	2 / 3	Withdrawn	1
DB16104	Batoclimab	3	Recruiting	3
DB00763	Methimazole	3	Unknown Status	1
DB00550	Propylthiouracil	3	Unknown Status	1
DB15762	Satralizumab	3	Recruiting	2
DB09029	Secukinumab	3	Terminated	1
DB00641	Simvastatin	3	Recruiting	1
DB09153	Sodium chloride	3	Completed	1
DB06343	Teprotumumab	3	Completed	2
DB06343	Teprotumumab	3	Recruiting	1
DB06273	Tocilizumab	3	Completed	1
DB11105	Benzalkonium	4	Completed	1
DB00905	Bimatoprost	4	Completed	1
DB00905	Bimatoprost	4	Withdrawn	1
DB11326	Boric acid	4	Completed	1
DB00083	Botulinum toxin type A	4	Withdrawn	1
DB08818	Hyaluronic acid	4	Terminated	1
DB13366	Hydrochloric acid	4	Completed	1
DB01611	Hydroxychloroquine	4	Recruiting	1
DB11075	Hypromellose	4	Completed	1
DB00654	Latanoprost	4	Withdrawn	1
DB00959	Methylprednisolone	4	Unknown Status	2
DB00761	Potassium chloride	4	Completed	1
DB00635	Prednisone	4	Unknown Status	1
DB00550	Propylthiouracil	4	Unknown Status	1
DB14505	Sodium borate	4	Completed	1
DB09153	Sodium chloride	4	Completed	2
DB11151	Sodium hydroxide	4	Completed	1
DB08819	Tafluprost	4	Withdrawn	1
DB06343	Teprotumumab	4	Active Not Recruiting	1
DB06343	Teprotumumab	4	Completed	1
DB00373	Timolol	4	Withdrawn	1
DB00287	Travoprost	4	Withdrawn	1
DB09145	Water	4	Completed	1
DB01200	Bromocriptine	Not Available	Terminated	1
DB00389	Carbimazole	Not Available	Completed	1
DB05382	Iodine	Not Available	Completed	1
DB00763	Methimazole	Not Available	Terminated	1
DB00959	Methylprednisolone	Not Available	Active Not Recruiting	1
DB00959	Methylprednisolone	Not Available	Completed	5
DB00806	Pentoxifylline	Not Available	Terminated	1
DB00877	Sirolimus	Not Available	Completed	1
DB00706	Tamsulosin	Not Available	Recruiting	1
DB06343	Teprotumumab	Not Available	Approved for Marketing	1
DB06343	Teprotumumab	Not Available	Recruiting	1
DB06273	Tocilizumab	Not Available	Recruiting	1