Anaphylaxis

Also known as: Anaphylaxis reaction / Anaphylactic Reaction / Anaphylactic responses / Anaphylaxis reactions / Anaphylactic symptoms / Anaphylactic / Anaphylactic-type reactions / Anaphylactic reactions / Anaphylactic shock / Allergic shock / Systemic anaphylaxis / Systemic anaphylactic reaction

DrugDrug NameDrug Description
DB00748CarbinoxamineA first generation antihistamine used to treat allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, allergic reactions, and mild allergic reactions.
DB00434CyproheptadineA combined serotonin and histamine antagonist used in the treatment of allergic symptoms, for appetite stimulation, and off-label in the treatment of serotonin syndrome.
DB08801DimetindeneA 1st generation selective H1 antagonist used topically as an antipruritic and orally to treat allergies.
DB01075DiphenhydramineA H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.
DB00668EpinephrineA hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
DB14542Hydrocortisone phosphateA corticosteroid used to treat congenital adrenal hyperplasia, for emergency asthma treatment, hypersensitivity, and inflammation.
DB01620PheniramineAn antihistamine used to treat allergic rhinitis and pruritus.
DB14633Prednisolone hemisuccinateA corticosteroid indicated in the treatment of anaphylaxis, asthma, edema, organ rejection, and other indications.
DB01069PromethazineA first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness.
DrugDrug NameTargetType
DB00748CarbinoxamineHistamine H1 receptortarget
DB00434Cyproheptadine5-hydroxytryptamine receptor 2Atarget
DB00434CyproheptadineHistamine H1 receptortarget
DB00434CyproheptadineMuscarinic acetylcholine receptor M1target
DB00434CyproheptadineMuscarinic acetylcholine receptor M2target
DB00434CyproheptadineMuscarinic acetylcholine receptor M3target
DB00434Cyproheptadine5-hydroxytryptamine receptor 2Ctarget
DB00434CyproheptadineUDP-glucuronosyltransferase 1-3enzyme
DB00434Cyproheptadine5-hydroxytryptamine receptor 7target
DB00434CyproheptadineUDP-glucuronosyltransferase 2B10enzyme
DB00434CyproheptadineUDP-glucuronosyltransferase 1-4enzyme
DB00434Cyproheptadine5-hydroxytryptamine receptor 2Btarget
DB00434CyproheptadineHistamine H2 receptortarget
DB00434CyproheptadineSolute carrier family 22 member 1transporter
DB00434CyproheptadineSerum albumincarrier
DB08801DimetindeneMuscarinic acetylcholine receptor M2target
DB08801DimetindeneHistamine H1 receptortarget
DB01075DiphenhydramineHistamine H1 receptortarget
DB01075DiphenhydramineCytochrome P450 2D6enzyme
DB01075DiphenhydramineCytochrome P450 2C9enzyme
DB01075DiphenhydramineCytochrome P450 2C19enzyme
DB01075DiphenhydramineSolute carrier family 22 member 2transporter
DB01075DiphenhydramineSolute carrier family 22 member 5transporter
DB01075DiphenhydramineProstaglandin G/H synthase 1enzyme
DB01075DiphenhydramineMuscarinic acetylcholine receptor M2target
DB00668EpinephrineAlpha-1A adrenergic receptortarget
DB00668EpinephrineBeta-1 adrenergic receptortarget
DB00668EpinephrineBeta-2 adrenergic receptortarget
DB00668EpinephrineSolute carrier family 22 member 2transporter
DB00668EpinephrineSolute carrier family 22 member 1transporter
DB00668EpinephrineCytochrome P450 2C9enzyme
DB00668EpinephrineCytochrome P450 3A4enzyme
DB00668EpinephrineAlpha-1B adrenergic receptortarget
DB00668EpinephrineAlpha-1D adrenergic receptortarget
DB00668EpinephrineAlpha-2A adrenergic receptortarget
DB00668EpinephrineAlpha-2B adrenergic receptortarget
DB00668EpinephrineTumor necrosis factortarget
DB00668EpinephrineCatechol O-methyltransferaseenzyme
DB00668EpinephrineMonoamine oxidaseenzyme
DB14542Hydrocortisone phosphateAnnexin A1target
DB14542Hydrocortisone phosphateGlucocorticoid receptortarget
DB14542Hydrocortisone phosphateSex hormone-binding globulincarrier
DB14542Hydrocortisone phosphateCytochrome P450 3A4enzyme
DB14542Hydrocortisone phosphateCytochrome P450 3A5enzyme
DB14542Hydrocortisone phosphateCytochrome P450 3A7enzyme
DB14542Hydrocortisone phosphateP-glycoprotein 1transporter
DB14542Hydrocortisone phosphateSolute carrier organic anion transporter family member 1A2transporter
DB14542Hydrocortisone phosphateATP-binding cassette sub-family G member 2transporter
DB14542Hydrocortisone phosphateCytochrome P450 2C8enzyme
DB14542Hydrocortisone phosphateCorticosteroid-binding globulincarrier
DB14542Hydrocortisone phosphateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14542Hydrocortisone phosphate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14542Hydrocortisone phosphateSolute carrier family 22 member 8transporter
DB01620PheniramineHistamine H1 receptortarget
DB01620PheniramineNuclear receptor subfamily 1 group I member 3target
DB01620PheniramineHistamine H4 receptortarget
DB14633Prednisolone hemisuccinateCytochrome P450 3A4enzyme
DB14633Prednisolone hemisuccinateCytochrome P450 3A5enzyme
DB01069PromethazineDopamine D2 receptortarget
DB01069PromethazineHistamine H1 receptortarget
DB01069PromethazineMuscarinic acetylcholine receptor M4target
DB01069PromethazineMuscarinic acetylcholine receptor M1target
DB01069PromethazineMuscarinic acetylcholine receptor M5target
DB01069PromethazineMuscarinic acetylcholine receptor M2target
DB01069PromethazineMuscarinic acetylcholine receptor M3target
DB01069PromethazineCalmodulintarget
DB01069PromethazineCytochrome P450 2D6enzyme
DB01069PromethazineCytochrome P450 2B6enzyme
DB01069PromethazineP-glycoprotein 1transporter
DB01069PromethazineCytochrome P450 2C9enzyme
DB01069PromethazineHistamine H2 receptortarget
DB01069PromethazineAlpha adrenergic receptortarget
DB01069PromethazineP2 Purinoceptorstarget
DB01069PromethazineVoltage-gated sodium channel alpha subunittarget
DB01069PromethazineVoltage-gated Potassium Channelstarget
DB01069PromethazineCanalicular multispecific organic anion transporter 2transporter
DB01069PromethazineMultidrug resistance-associated protein 4transporter
DB01069PromethazineSerum albumincarrier
DrugDrug NamePhaseStatusCount
DB01234Dexamethasone1Recruiting1
DB00668Epinephrine1Recruiting1
DB06206Sugammadex1Completed1
DB09536Titanium dioxide1Recruiting1
DB09321Zinc oxide1Recruiting1
DB00668Epinephrine2Completed1
DB00043Omalizumab2Completed1
DB15696Pfizer-BioNTech COVID-19 Vaccine3Not Yet Recruiting1
DB00668Epinephrine4Completed2
DB01001Salbutamol4Completed1
DB00668EpinephrineNot AvailableCompleted1
DB01109HeparinNot AvailableWithdrawn1
DB09536Titanium dioxideNot AvailableSuspended1
DB09321Zinc oxideNot AvailableSuspended1