Lennox Gastaut Syndrome
Also known as: Lennox Gastaut Syndrome (LGS) / Lennox-Gastaut Syndrome / Lennox-Gastaut Syndrome (LGS) / Lennox-Gastaut syndrome (disorder) / Cutis verticis gyrata / Cutis verticis gyrata (disorder)
| Drug | Drug Name | Drug Description |
|---|---|---|
| DB09061 | Cannabidiol | An active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer. |
| DB00349 | Clobazam | A benzodiazepine used as adjunct treatment in seizures associated with Lennox-Gastaut syndrome. |
| DB01068 | Clonazepam | A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, and seizures. |
| DB00574 | Fenfluramine | Fenfluramine is a phenethylamine that is structurally similar to serotonin. Due to its ability to increase extracellular serotonin levels, modulate serotonergic and other neurologic receptors, and control neurotransmission, it is effective in treating pharmacoresistant seizures. |
| DB00555 | Lamotrigine | A phenyltriazine antiepileptic used to treat some types of epilepsy and bipolar I disorder. |
| DB06201 | Rufinamide | An antiepileptic drug used as adjunctive therapy to treat seizures associated with Lennox-Gastaut Syndrome (LGS). |
| DB00273 | Topiramate | An anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines. |
| Drug | Drug Name | Phase | Status | Count |
|---|---|---|---|---|
| DB09061 | Cannabidiol | 1 | Completed | 1 |
| DB12338 | Carisbamate | 1 | Completed | 2 |
| DB00574 | Fenfluramine | 1 | Completed | 1 |
| DB09061 | Cannabidiol | 1 / 2 | Terminated | 1 |
| DB15932 | Clemizole | 2 | Not Yet Recruiting | 1 |
| DB00574 | Fenfluramine | 2 | Active Not Recruiting | 1 |
| DB16987 | Soticlestat | 2 | Active Not Recruiting | 1 |
| DB16987 | Soticlestat | 2 | Completed | 1 |
| DB09061 | Cannabidiol | 3 | Completed | 3 |
| DB09061 | Cannabidiol | 3 | Unknown Status | 1 |
| DB09061 | Cannabidiol | 3 | Withdrawn | 1 |
| DB12338 | Carisbamate | 3 | Recruiting | 1 |
| DB00349 | Clobazam | 3 | Completed | 1 |
| DB00574 | Fenfluramine | 3 | Active Not Recruiting | 2 |
| DB00334 | Olanzapine | 3 | Completed | 1 |
| DB08883 | Perampanel | 3 | Terminated | 1 |
| DB06201 | Rufinamide | 3 | Completed | 3 |
| DB16987 | Soticlestat | 3 | Completed | 1 |
| DB16987 | Soticlestat | 3 | Recruiting | 1 |
| DB00273 | Topiramate | 3 | Completed | 1 |
| DB09061 | Cannabidiol | 4 | Recruiting | 1 |
| DB09061 | Cannabidiol | 4 | Withdrawn | 1 |
| DB16956 | L-Acetylleucine | 4 | Withdrawn | 1 |
| DB01065 | Melatonin | 4 | Withdrawn | 1 |
| DB09061 | Cannabidiol | Not Available | Not Yet Recruiting | 1 |
| DB08883 | Perampanel | Not Available | Available | 1 |
| DB06201 | Rufinamide | Not Available | Available | 1 |
| DB06201 | Rufinamide | Not Available | Completed | 1 |