Dyspepsia

Also known as: Sour stomach / Acid Dyspepsia / Indigestion / Indigestion NOS (finding) / Indigestion (finding) / Dyspepsia (disorder) [Ambiguous] / Dyspepsia (& [flatulent] or [NOS]) / (Dyspepsia, indigestion NOS) or (dyspepsia) or (hyperacidity)

DrugDrug NameDrug Description
DB13518Alginic acidIndicated for the management of gastric reflux, reflux oesophagitis, hiatus hernia, heartburn (including heartburn of pregnancy) and similar gastric distress .
DB13595AlmasilateAlmasilate is indicated for use as an antacid for the neutralization of excess stomach acid . It is subsequently also used for the symptomatic treatment of diseases where it is...
DB13626Aluminium glycinateA medication indicated to treat heartburn, indigestion, acid reflux, ulcers, and gas.
DB14517Aluminium phosphateNot Available
DB06723Aluminum hydroxideAn antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach.
DB15776Anise oilNot Annotated
DB01294Bismuth subsalicylateAn antidiarrheal and anti-inflammatory agent used for symptomatic treatment of nausea, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
DB00201CaffeineA stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth.
DB06724Calcium carbonateAn ionic compound used as a calcium supplement or antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach.
DB00501CimetidineA histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
DB08810CinitaprideA benzamide with gastroprokinetic and antiemetic properties typically used for the treatment of gastrointestinal motility disorders such as gastroesophageal reflux disease (GERD), non-ulcer dyspepsia, and delayed gastric emptying.
DB11622Dehydrocholic acidNo approved therapeutic indications.
DB11074DimethiconeAn ingredient used to treat dry and irritated eyes.
DB01184DomperidoneA dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting.
DB14225Enterococcus faeciumNot Annotated
DB00927FamotidineA histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.
DB07118HymecromoneA coumarin derivative that lacks anticoagulant properties but possesses choleretic and biliary antispasmodic activity.
DB04924ItoprideAn acetylcholine esterase inhibitor and dopamine D2 receptor antagonist used to treat symptoms of functional dyspepsia such as nausea and vomiting.
DB16021Levosulpirideindicated to treat dyspepsia, symptoms of Meniere's syndrome, and second line in the treatment of drug-induced nausea and vomiting.
DB08938MagaldrateAn antacid used to treat various conditions in the GI tract, such as esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux.
DB09104Magnesium hydroxideAn inorganic compound used as a laxative and antacid.
DB01233MetoclopramideAn antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.
DB14016Ox bile extractNot Annotated
DB00085PancrelipaseA purified form of porcine pancreatic lipase, amylase, and protease enzymes used to treat malabsorption associated with pancreatic insufficiency resulting from cystic fibrosis and pancreatitis.
DB13844PipenzolateAn antimuscarinic agent indicated in the treatment of gastrointestinal motility disorders and arrhythmia.
DB14116SilodrateNot Annotated
DB09512SimethiconeAn anti-flatulence agent used to relieve pressure, bloating, and symptoms referred to as gas.
DB01390Sodium bicarbonateA compound used for the symptomatic treatment of heartburn, acid indigestion, and upset stomach as well as the treatment of metabolic acidosis associated with conditions such as severe renal disease and circulatory insufficiency due to shock.
DB00364SucralfateA gastro-duodenal protective agent used in the treatment of gastric and duodenal ulcers and to prevent duodenal ulcer recurrence.
DB00391SulpirideA selective D2 dopamine receptor antagonist indicated to treat chronic and acute schizophrenia.
DrugDrug NameTargetType
DB14517Aluminium phosphateSerotransferrintarget
DB14517Aluminium phosphateSodium/potassium-transporting ATPase subunit alpha-1target
DB14517Aluminium phosphateSerum albumincarrier
DB14517Aluminium phosphateKallikrein-1target
DB14517Aluminium phosphateAmyloid beta A4 proteintarget
DB01294Bismuth subsalicylateSerum albumincarrier
DB01294Bismuth subsalicylateSerotransferrincarrier
DB00201CaffeineAdenosine receptor A1target
DB00201CaffeinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00201CaffeineAdenosine receptor A2atarget
DB00201CaffeineCytochrome P450 1A2enzyme
DB00201CaffeineRyanodine receptor 1target
DB00201CaffeineCytochrome P450 3A4enzyme
DB00201CaffeineCytochrome P450 2E1enzyme
DB00201CaffeineCytochrome P450 2C8enzyme
DB00201CaffeineCytochrome P450 2C9enzyme
DB00201CaffeineCytochrome P450 1A1enzyme
DB00201CaffeineCytochrome P450 1B1enzyme
DB00201CaffeineCytochrome P450 2D6enzyme
DB00201CaffeineCyclic nucleotide phosphodiesterasetarget
DB00201CaffeineDNA-dependent protein kinase catalytic subunittarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformtarget
DB00201CaffeineInositol 1,4,5-trisphosphate receptortarget
DB00201CaffeineSerine-protein kinase ATMtarget
DB00201CaffeineATP-binding cassette sub-family G member 2transporter
DB00201CaffeineAdenosine receptor A2btarget
DB00201CaffeineAdenosine receptor A3target
DB00201CaffeinePhosphodiesterase enzymestarget
DB00501CimetidineHistamine H2 receptortarget
DB00501CimetidineCytochrome P450 1A2enzyme
DB00501CimetidineCytochrome P450 2D6enzyme
DB00501CimetidineCytochrome P450 2C19enzyme
DB00501CimetidineCytochrome P450 3A4enzyme
DB00501CimetidineCytochrome P450 3A5enzyme
DB00501CimetidineP-glycoprotein 1transporter
DB00501CimetidineSolute carrier family 22 member 2transporter
DB00501CimetidineSolute carrier family 22 member 1transporter
DB00501CimetidineSolute carrier family 22 member 3transporter
DB00501CimetidineSolute carrier family 22 member 5transporter
DB00501CimetidineSolute carrier family 22 member 6transporter
DB00501CimetidineSolute carrier family 22 member 8transporter
DB00501CimetidineMultidrug and toxin extrusion protein 1transporter
DB00501CimetidineSolute carrier family 22 member 4transporter
DB00501CimetidineSolute carrier family 22 member 11transporter
DB00501CimetidineSolute carrier family 22 member 7transporter
DB00501CimetidineCytochrome P450 11B1, mitochondrialenzyme
DB00501CimetidineCytochrome P450 2C8enzyme
DB00501CimetidineCytochrome P450 2C9enzyme
DB00501CimetidineCytochrome P450 2E1enzyme
DB00501CimetidineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00501CimetidineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00501CimetidineBile salt export pumptransporter
DB00501CimetidineMultidrug and toxin extrusion protein 2transporter
DB00501CimetidineSerum albumincarrier
DB08810Cinitapride5-hydroxytryptamine receptor 1Atarget
DB08810Cinitapride5-hydroxytryptamine receptor 4target
DB08810Cinitapride5-hydroxytryptamine receptor 2Atarget
DB01184DomperidoneDopamine D2 receptortarget
DB01184DomperidoneCytochrome P450 3A4enzyme
DB01184DomperidoneCytochrome P450 3A5enzyme
DB01184DomperidoneCytochrome P450 3A7enzyme
DB01184DomperidoneP-glycoprotein 1transporter
DB01184DomperidoneCytochrome P450 1A2enzyme
DB01184DomperidoneCytochrome P450 2B6enzyme
DB01184DomperidoneCytochrome P450 2C8enzyme
DB01184DomperidoneCytochrome P450 2D6enzyme
DB01184DomperidoneDopamine D3 receptortarget
DB00927FamotidineHistamine H2 receptortarget
DB00927FamotidineSolute carrier family 22 member 2transporter
DB00927FamotidineSolute carrier family 22 member 8transporter
DB00927FamotidineMultidrug and toxin extrusion protein 1transporter
DB00927FamotidineCytochrome P450 1A2enzyme
DB00927FamotidineSolute carrier family 22 member 6transporter
DB07118HymecromoneArylsulfate sulfotransferasetarget
DB04924ItoprideDopamine D2 receptortarget
DB04924ItoprideAcetylcholinesterasetarget
DB01233MetoclopramideMuscarinic acetylcholine receptor M1target
DB01233MetoclopramideDopamine D2 receptortarget
DB01233MetoclopramideCytochrome P450 2D6enzyme
DB01233Metoclopramide5-hydroxytryptamine receptor 4target
DB01233Metoclopramide5-hydroxytryptamine receptor 3Atarget
DB01233MetoclopramideCytochrome P450 3A4enzyme
DB01233MetoclopramideCytochrome P450 1A2enzyme
DB01233MetoclopramideP-glycoprotein 1transporter
DB01233MetoclopramideAlpha-1-acid glycoprotein 1carrier
DB00085PancrelipaseDietary fattarget
DB00085PancrelipaseDietary proteintarget
DB00085PancrelipaseDietary starchtarget
DB01390Sodium bicarbonateElectrogenic sodium bicarbonate cotransporter 1transporter
DB01390Sodium bicarbonateSodium bicarbonate cotransporter 3transporter
DB01390Sodium bicarbonateElectroneutral sodium bicarbonate exchanger 1transporter
DB01390Sodium bicarbonateElectrogenic sodium bicarbonate cotransporter 4transporter
DB01390Sodium bicarbonateHydrogen ionstarget
DB01390Sodium bicarbonateSodium-driven chloride bicarbonate exchangertransporter
DB00364SucralfateFibrinogentarget
DB00364SucralfatePepsin A-5target
DB00364SucralfatePro-epidermal growth factortarget
DB00364SucralfateFibroblast growth factor 2target
DB00391SulpirideDopamine D2 receptortarget
DB00391SulpirideDopamine D3 receptortarget
DB00391SulpirideCholinesteraseenzyme
DB00391SulpirideCarbonic anhydrase 2target
DB00391SulpirideCarbonic anhydrase 3target
DB00391SulpirideSerum albumincarrier
DB00391SulpirideSolute carrier family 22 member 1transporter
DB00391SulpirideSolute carrier family 22 member 2transporter
DB00391SulpirideMultidrug and toxin extrusion protein 1transporter
DB00391SulpirideMultidrug and toxin extrusion protein 2transporter
DB00391SulpirideDopamine D4 receptortarget
DB00391SulpirideSolute carrier family 22 member 3transporter
DB00391SulpirideP-glycoprotein 1transporter
DB00391SulpirideATP-binding cassette sub-family G member 2transporter
DrugDrug NamePhaseStatusCount
DB01060Amoxicillin0Completed1
DB01211Clarithromycin0Completed1
DB00338Omeprazole0Completed1
DB16036ABX-14311Terminated1
DB16021Levosulpiride1Completed1
DB12355Netazepide1Completed1
DB00736Esomeprazole1 / 2Unknown Status1
DB00448Lansoprazole1 / 2Unknown Status1
DB00338Omeprazole1 / 2Unknown Status1
DB09532Secretin human1 / 2Completed1
DB01586Ursodeoxycholic acid1 / 2Recruiting1
DB01060Amoxicillin2Completed1
DB01060Amoxicillin2Unknown Status1
DB09061Cannabidiol2Recruiting1
DB01211Clarithromycin2Unknown Status1
DB04856Dexloxiglumide2Completed1
DB00736Esomeprazole2Completed3
DB00736Esomeprazole2Unknown Status1
DB09047Finafloxacin2Completed1
DB00338Omeprazole2Terminated1
DB00904Ondansetron2Recruiting1
DB15417Recanaclotide2Terminated1
DB01220Rifaximin2Not Yet Recruiting1
DB12482Acotiamide3Completed2
DB13518Alginic acid3Completed1
DB01060Amoxicillin3Completed1
DB09018Bromopride3Completed1
DB06724Calcium carbonate3Completed1
DB08810Cinitapride3Completed1
DB11074Dimethicone3Completed1
DB01184Domperidone3Completed1
DB01184Domperidone3Recruiting1
DB00254Doxycycline3Recruiting1
DB01175Escitalopram3Completed1
DB00736Esomeprazole3Completed4
DB00736Esomeprazole3Recruiting1
DB04924Itopride3Completed4
DB01137Levofloxacin3Recruiting1
DB00281Lidocaine3Completed1
DB00788Naproxen3Completed1
DB04743Nimesulide3Completed1
DB00507Nitazoxanide3Recruiting1
DB11062Octisalate3Completed1
DB09535Octocrylene3Completed1
DB00338Omeprazole3Completed1
DB00338Omeprazole3Recruiting1
DB00213Pantoprazole3Completed1
DB01129Rabeprazole3Completed1
DB11656Rebamipide3Completed1
DB00615Rifabutin3Completed1
DB01390Sodium bicarbonate3Completed1
DB09372Tannic acid3Completed1
DB01079Tegaserod3Completed6
DB09321Zinc oxide3Completed1
DB00945Acetylsalicylic acid4Completed1
DB13518Alginic acid4Completed1
DB06723Aluminum hydroxide4Completed1
DB01060Amoxicillin4Completed3
DB01060Amoxicillin4Enrolling by Invitation2
DB01060Amoxicillin4Not Yet Recruiting1
DB00207Azithromycin4Completed1
DB04115Berberine4Completed2
DB04115Berberine4Enrolling by Invitation1
DB00490Buspirone4Completed1
DB09300Butylscopolamine4Completed1
DB01211Clarithromycin4Completed4
DB01211Clarithromycin4Enrolling by Invitation1
DB01211Clarithromycin4Not Yet Recruiting1
DB01003Cromoglicic acid4Unknown Status1
DB01184Domperidone4Completed1
DB00668Epinephrine4Recruiting1
DB00736Esomeprazole4Completed4
DB00736Esomeprazole4Enrolling by Invitation1
DB00736Esomeprazole4Unknown Status3
DB00736Esomeprazole4Withdrawn1
DB00927Famotidine4Unknown Status1
DB00875Flupentixol4Completed1
DB00614Furazolidone4Enrolling by Invitation1
DB13322Hydrotalcite4Completed1
DB00448Lansoprazole4Completed2
DB09481Magnesium carbonate4Completed1
DB13384Melitracen4Completed1
DB00916Metronidazole4Completed1
DB00338Omeprazole4Completed2
DB00213Pantoprazole4Completed2
DB09125Potassium citrate4Completed1
DB01129Rabeprazole4Enrolling by Invitation1
DB00863Ranitidine4Completed2
DB00863Ranitidine4Withdrawn1
DB11656Rebamipide4Unknown Status1
DB09153Sodium chloride4Recruiting1
DB00364Sucralfate4Completed1
DB16690Tegoprazan4Not Yet Recruiting1
DB00759Tetracycline4Enrolling by Invitation1
DB12482AcotiamideNot AvailableCompleted1
DB06723Aluminum hydroxideNot AvailableCompleted1
DB09393Amino acidsNot AvailableCompleted1
DB00321AmitriptylineNot AvailableTerminated1
DB01060AmoxicillinNot AvailableCompleted1
DB00155CitrullineNot AvailableCompleted1
DB01211ClarithromycinNot AvailableCompleted1
DB01151DesipramineNot AvailableTerminated1
DB01184DomperidoneNot AvailableTerminated1
DB00736EsomeprazoleNot AvailableRecruiting1
DB11242GelatinNot AvailableCompleted1
DB04924ItoprideNot AvailableCompleted1
DB16021LevosulpirideNot AvailableCompleted1
DB01377Magnesium oxideNot AvailableCompleted1
DB00471MontelukastNot AvailableCompleted1
DB00540NortriptylineNot AvailableTerminated1
DB00338OmeprazoleNot AvailableCompleted1
DB00338OmeprazoleNot AvailableWithdrawn1
DB00107OxytocinNot AvailableCompleted1
DB00213PantoprazoleNot AvailableCompleted2
DB13198PepsinNot AvailableCompleted1
DB06480PrucaloprideNot AvailableCompleted1
DB00863RanitidineNot AvailableCompleted1
DB14744Spirulina platensisNot AvailableCompleted1
DB00364SucralfateNot AvailableWithdrawn1
DB00285VenlafaxineNot AvailableCompleted1