Pyoderma Gangrenosum

Also known as: Phagedenic pyoderma / Pyoderma gangrenous / Pyoderma gangrenosum (disorder) / Pyoderma gangenosum

Drug	Drug Name	Drug Description
DB00051	Adalimumab	A monoclonal anti-tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis.
DB00005	Etanercept	A protein therapy based on the binding fragment of the tumour necrosis factor alpha receptor used to treat severe rheumatoid arthritis and moderate to severe plaque psoriasis.
DB00798	Gentamicin	An aminoglycoside used to treat a wide variety of aerobic infections in the body.
DB00864	Tacrolimus	A calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis.

Drug	Drug Name	Target	Type
DB00051	Adalimumab	Tumor necrosis factor	target
DB00005	Etanercept	Tumor necrosis factor	target
DB00005	Etanercept	Lymphotoxin-alpha	target
DB00005	Etanercept	Low affinity immunoglobulin gamma Fc region receptor III-B	target
DB00005	Etanercept	Low affinity immunoglobulin gamma Fc region receptor III-A	target
DB00005	Etanercept	High affinity immunoglobulin gamma Fc receptor I	target
DB00005	Etanercept	Low affinity immunoglobulin gamma Fc region receptor II-a	target
DB00005	Etanercept	Low affinity immunoglobulin gamma Fc region receptor II-b	target
DB00005	Etanercept	Low affinity immunoglobulin gamma Fc region receptor II-c	target
DB00005	Etanercept	Complement component 1q (C1q)	target
DB00798	Gentamicin	30S ribosomal protein S12	target
DB00798	Gentamicin	16S ribosomal RNA	target
DB00798	Gentamicin	NH(3)-dependent NAD(+) synthetase	target
DB00798	Gentamicin	Dihydrofolate reductase	target
DB00798	Gentamicin	23S ribosomal RNA	target
DB00798	Gentamicin	Bacterial outer membrane	target
DB00798	Gentamicin	Cytoplasmic membrane	target
DB00798	Gentamicin	Low-density lipoprotein receptor-related protein 2	transporter
DB00798	Gentamicin	Solute carrier family 22 member 2	transporter
DB00798	Gentamicin	Canalicular multispecific organic anion transporter 1	transporter
DB00864	Tacrolimus	Peptidyl-prolyl cis-trans isomerase FKBP1A	target
DB00864	Tacrolimus	Cytochrome P450 3A4	enzyme
DB00864	Tacrolimus	Cytochrome P450 3A5	enzyme
DB00864	Tacrolimus	P-glycoprotein 1	transporter
DB00864	Tacrolimus	ATP-binding cassette sub-family A member 5	transporter
DB00864	Tacrolimus	Serum albumin	carrier
DB00864	Tacrolimus	Alpha-1-acid glycoprotein 1	carrier
DB00864	Tacrolimus	Solute carrier organic anion transporter family member 1B1	transporter

Drug	Drug Name	Phase	Status	Count
DB16650	Deucravacitinib	0	Not Yet Recruiting	1
DB09029	Secukinumab	1 / 2	Completed	1
DB00051	Adalimumab	2	Withdrawn	2
DB11817	Baricitinib	2	Recruiting	1
DB06168	Canakinumab	2	Completed	1
DB14766	Etrasimod	2	Terminated	1
DB12119	Gevokizumab	2	Completed	1
DB11569	Ixekizumab	2	Completed	1
DB09029	Secukinumab	2	Withdrawn	1
DB15626	Spesolimab	2	Recruiting	1
DB16416	Vilobelimab	2	Completed	1
DB00051	Adalimumab	3	Completed	1
DB12119	Gevokizumab	3	Terminated	3
DB16416	Vilobelimab	3	Recruiting	1
DB00065	Infliximab	Not Available	Completed	1