Myelofibrosis

Also known as: Myelofibroses / Agnogenic Myeloid Metaplasia / Myelofibrosis，MF / Myelofibrosis (MF) / Indolent Non-follicular / Myelosis non-leukemic / Myelofibrosis (disorder) / (Other blood diseases NOS) or (myelofibrosis) / Myelosis-non-leukaemic / Myelosis non-leukaemic / Myelosis nonleukemic / Myelosclerosis / Osteomyelofibrosis / Primary myelofibrosis / Myelosclerosis with myeloid metaplasia (disorder) / Myelosclerosis with myeloid metaplasia -RETIRED- / Myelosclerosis with myeloid metaplasia / Myelosclerosis with myeloid metaplasia (morphologic abnormality)

Drug	Drug Name	Drug Description
DB06412	Oxymetholone	An anabolic steroid used for the treatment of types of anemia, such as acquired aplastic anemia, congenital aplastic anemia, myelofibrosis, and the hypoplastic anemias.

Drug	Drug Name	Target	Type
DB06412	Oxymetholone	Androgen receptor	target
DB06412	Oxymetholone	Serum albumin	carrier
DB06412	Oxymetholone	Sex hormone-binding globulin	carrier
DB06412	Oxymetholone	Natriuretic peptides B	target
DB06412	Oxymetholone	Amine oxidase [flavin-containing] A	enzyme
DB06412	Oxymetholone	Cytochrome P450 2D6	enzyme
DB06412	Oxymetholone	3-oxo-5-alpha-steroid 4-dehydrogenase 1	enzyme
DB06412	Oxymetholone	Cytochrome P450 3A4	enzyme
DB06412	Oxymetholone	Cytochrome P450 3A5	enzyme
DB06412	Oxymetholone	Cytochrome P450 3A7	enzyme
DB06412	Oxymetholone	Cytochrome P450 3A43	enzyme

Drug	Drug Name	Phase	Status	Count
DB01169	Arsenic trioxide	0	Completed	1
DB00531	Cyclophosphamide	0	Completed	1
DB00091	Cyclosporine	0	Completed	1
DB00987	Cytarabine	0	Completed	1
DB01073	Fludarabine	0	Completed	1
DB00688	Mycophenolate mofetil	0	Completed	1
DB09036	Siltuximab	0	Withdrawn	1
DB11720	Angiotensin 1-7	1	Terminated	1
DB09312	Antilymphocyte immunoglobulin (horse)	1	Completed	1
DB00098	Antithymocyte immunoglobulin (rabbit)	1	Active Not Recruiting	1
DB00098	Antithymocyte immunoglobulin (rabbit)	1	Completed	1
DB11945	Avelumab	1	Active Not Recruiting	1
DB00928	Azacitidine	1	Completed	1
DB00928	Azacitidine	1	Recruiting	1
DB11666	Buparlisib	1	Terminated	1
DB01008	Busulfan	1	Active Not Recruiting	1
DB01008	Busulfan	1	Completed	2
DB00515	Cisplatin	1	Active Not Recruiting	1
DB00631	Clofarabine	1	Terminated	1
DB09110	Coenzyme M	1	Completed	2
DB00531	Cyclophosphamide	1	Completed	2
DB00531	Cyclophosphamide	1	Terminated	1
DB01262	Decitabine	1	Recruiting	1
DB01262	Decitabine	1	Withdrawn	2
DB06165	Fedratinib	1	Completed	1
DB00099	Filgrastim	1	Completed	1
DB01073	Fludarabine	1	Active Not Recruiting	1
DB01073	Fludarabine	1	Completed	3
DB12396	Fresolimumab	1	Terminated	1
DB13040	Gandotinib	1	Completed	1
DB05036	Grn163l	1	Recruiting	1
DB16054	INCB-057643	1	Recruiting	1
DB09054	Idelalisib	1	Terminated	1
DB14909	Imetelstat	1	Recruiting	1
DB06186	Ipilimumab	1	Recruiting	1
DB17545	Jaktinib	1	Recruiting	1
DB05608	MKC-1	1	Completed	1
DB01042	Melphalan	1	Completed	1
DB00563	Methotrexate	1	Active Not Recruiting	1
DB00563	Methotrexate	1	Completed	1
DB00688	Mycophenolate mofetil	1	Completed	1
DB00688	Mycophenolate mofetil	1	Terminated	1
DB01024	Mycophenolic acid	1	Completed	1
DB12340	Navitoclax	1	Recruiting	2
DB12340	Navitoclax	1	Terminated	1
DB17561	Nisevokitug	1	Withdrawn	1
DB11697	Pacritinib	1	Completed	2
DB11697	Pacritinib	1	Withdrawn	1
DB00642	Pemetrexed	1	Active Not Recruiting	1
DB11759	Pevonedistat	1	Terminated	1
DB11730	Ribociclib	1	Completed	1
DB08877	Ruxolitinib	1	Active Not Recruiting	2
DB08877	Ruxolitinib	1	Completed	3
DB08877	Ruxolitinib	1	Recruiting	3
DB08877	Ruxolitinib	1	Terminated	5
DB16322	Sabatolimab	1	Withdrawn	1
DB11689	Selumetinib	1	Recruiting	1
DB00877	Sirolimus	1	Terminated	1
DB14892	Spartalizumab	1	Withdrawn	1
DB12756	TAK-901	1	Completed	1
DB00864	Tacrolimus	1	Completed	2
DB14731	Tagraxofusp	1	Recruiting	1
DB04572	Thiotepa	1	Completed	1
DB14989	Umbralisib	1	Active Not Recruiting	1
DB11581	Venetoclax	1	Recruiting	1
DB08828	Vismodegib	1	Completed	1
DB05243	XL019	1	Terminated	1
DB12638	Zelavespib	1	Terminated	1
DB05169	AT9283	1 / 2	Terminated	1
DB06151	Acetylcysteine	1 / 2	Active Not Recruiting	1
DB00928	Azacitidine	1 / 2	Terminated	1
DB15435	BMS-986158	1 / 2	Recruiting	1
DB15271	Crizanlizumab	1 / 2	Active Not Recruiting	1
DB00987	Cytarabine	1 / 2	Recruiting	1
DB00694	Daunorubicin	1 / 2	Recruiting	1
DB01590	Everolimus	1 / 2	Completed	1
DB06165	Fedratinib	1 / 2	Completed	1
DB12500	Fedratinib	1 / 2	Completed	1
DB12500	Fedratinib	1 / 2	Recruiting	1
DB15670	Gusacitinib	1 / 2	Terminated	1
DB00619	Imatinib	1 / 2	Completed	1
DB17545	Jaktinib	1 / 2	Terminated	1
DB06469	Lestaurtinib	1 / 2	Unknown Status	1
DB15299	Navtemadlin	1 / 2	Recruiting	2
DB17561	Nisevokitug	1 / 2	Active Not Recruiting	1
DB17510	PXS-5505	1 / 2	Recruiting	1
DB11697	Pacritinib	1 / 2	Completed	2
DB06603	Panobinostat	1 / 2	Completed	1
DB00008	Peginterferon alfa-2a	1 / 2	Completed	1
DB17129	Pelabresib anhydrous	1 / 2	Active Not Recruiting	1
DB16285	Pelcitoclax	1 / 2	Withdrawn	1
DB17560	Rineterkib	1 / 2	Active Not Recruiting	1
DB08877	Ruxolitinib	1 / 2	Active Not Recruiting	2
DB08877	Ruxolitinib	1 / 2	Completed	3
DB08877	Ruxolitinib	1 / 2	Recruiting	4
DB08877	Ruxolitinib	1 / 2	Withdrawn	1
DB16322	Sabatolimab	1 / 2	Active Not Recruiting	1
DB16331	Siremadlin	1 / 2	Active Not Recruiting	1
DB04879	Vatalanib	1 / 2	Completed	1
DB01955	1,4-Butanediol	2	Completed	1
DB11740	Adavosertib	2	Terminated	1
DB00087	Alemtuzumab	2	Completed	1
DB09312	Antilymphocyte immunoglobulin (horse)	2	Terminated	1
DB00098	Antithymocyte immunoglobulin (rabbit)	2	Completed	1
DB00098	Antithymocyte immunoglobulin (rabbit)	2	Terminated	1
DB00928	Azacitidine	2	Completed	1
DB00074	Basiliximab	2	Completed	1
DB06769	Bendamustine	2	Completed	1
DB00112	Bevacizumab	2	Terminated	1
DB17234	Bomedemstat	2	Recruiting	1
DB00188	Bortezomib	2	Terminated	1
DB16741	Bortezomib D-mannitol	2	Terminated	1
DB01008	Busulfan	2	Completed	4
DB01008	Busulfan	2	Withdrawn	1
DB00958	Carboplatin	2	Active Not Recruiting	1
DB00531	Cyclophosphamide	2	Active Not Recruiting	2
DB00531	Cyclophosphamide	2	Completed	5
DB00531	Cyclophosphamide	2	Recruiting	1
DB00531	Cyclophosphamide	2	Withdrawn	1
DB00091	Cyclosporine	2	Active Not Recruiting	1
DB00091	Cyclosporine	2	Completed	1
DB00091	Cyclosporine	2	Withdrawn	1
DB01254	Dasatinib	2	Completed	1
DB16047	Elraglusib	2	Active Not Recruiting	1
DB12500	Fedratinib	2	Completed	1
DB00099	Filgrastim	2	Completed	1
DB01073	Fludarabine	2	Active Not Recruiting	2
DB01073	Fludarabine	2	Completed	7
DB01073	Fludarabine	2	Recruiting	1
DB01073	Fludarabine	2	Withdrawn	1
DB12010	Fostamatinib	2	Terminated	1
DB15126	IMG-7289	2	Completed	1
DB15126	IMG-7289	2	Recruiting	1
DB00619	Imatinib	2	Completed	1
DB14909	Imetelstat	2	Completed	1
DB05258	Interferon alfa	2	Terminated	1
DB12154	Itacitinib	2	Completed	1
DB12154	Itacitinib	2	Recruiting	2
DB17545	Jaktinib	2	Completed	1
DB17545	Jaktinib	2	Recruiting	1
DB00480	Lenalidomide	2	Completed	2
DB06469	Lestaurtinib	2	Completed	1
DB12070	Letermovir	2	Active Not Recruiting	1
DB01042	Melphalan	2	Completed	3
DB01042	Melphalan	2	Recruiting	1
DB16620	Methopterin	2	Withdrawn	1
DB00563	Methotrexate	2	Withdrawn	1
DB15483	Modified vaccinia ankara	2	Active Not Recruiting	3
DB15483	Modified vaccinia ankara	2	Withdrawn	1
DB00688	Mycophenolate mofetil	2	Active Not Recruiting	1
DB00688	Mycophenolate mofetil	2	Completed	3
DB00688	Mycophenolate mofetil	2	Recruiting	1
DB12340	Navitoclax	2	Active Not Recruiting	1
DB12191	Obatoclax	2	Completed	1
DB11697	Pacritinib	2	Active Not Recruiting	1
DB00008	Peginterferon alfa-2a	2	Terminated	1
DB00022	Peginterferon alfa-2b	2	Terminated	1
DB04977	Plitidepsin	2	Completed	1
DB08910	Pomalidomide	2	Completed	1
DB00635	Prednisone	2	Completed	2
DB12146	Rigosertib	2	Terminated	1
DB00073	Rituximab	2	Completed	1
DB15119	Ropeginterferon alfa-2b	2	Recruiting	1
DB08877	Ruxolitinib	2	Active Not Recruiting	4
DB08877	Ruxolitinib	2	Completed	2
DB08877	Ruxolitinib	2	Recruiting	2
DB08877	Ruxolitinib	2	Terminated	1
DB11942	Selinexor	2	Active Not Recruiting	1
DB12152	Simtuzumab	2	Completed	1
DB12118	Sotatercept	2	Completed	1
DB00864	Tacrolimus	2	Completed	2
DB00864	Tacrolimus	2	Recruiting	1
DB00864	Tacrolimus	2	Terminated	1
DB00864	Tacrolimus	2	Withdrawn	1
DB14731	Tagraxofusp	2	Completed	1
DB06285	Teriparatide	2	Terminated	1
DB01041	Thalidomide	2	Active Not Recruiting	1
DB17459	Therapeutic allogeneic lymphocytes	2	Completed	1
DB04572	Thiotepa	2	Active Not Recruiting	1
DB04572	Thiotepa	2	Completed	1
DB01030	Topotecan	2	Active Not Recruiting	1
DB07232	Veliparib	2	Active Not Recruiting	1
DB00399	Zoledronic acid	2	Completed	1
DB00531	Cyclophosphamide	3	Recruiting	1
DB01609	Deferasirox	3	Completed	1
DB12500	Fedratinib	3	Active Not Recruiting	2
DB00099	Filgrastim	3	Recruiting	1
DB01073	Fludarabine	3	Recruiting	1
DB05036	Grn163l	3	Recruiting	1
DB01005	Hydroxyurea	3	Recruiting	1
DB14909	Imetelstat	3	Recruiting	1
DB17545	Jaktinib	3	Recruiting	1
DB00688	Mycophenolate mofetil	3	Recruiting	1
DB12340	Navitoclax	3	Active Not Recruiting	1
DB12340	Navitoclax	3	Recruiting	1
DB14867	Parsaclisib	3	Active Not Recruiting	2
DB14867	Parsaclisib	3	Not Yet Recruiting	1
DB14867	Parsaclisib	3	Recruiting	1
DB17129	Pelabresib anhydrous	3	Active Not Recruiting	1
DB08877	Ruxolitinib	3	Active Not Recruiting	4
DB08877	Ruxolitinib	3	Completed	2
DB08877	Ruxolitinib	3	Not Yet Recruiting	1
DB08877	Ruxolitinib	3	Recruiting	3
DB00864	Tacrolimus	3	Recruiting	1
DB08877	Ruxolitinib	4	Recruiting	1
DB05220	Alisertib	Not Available	Active Not Recruiting	1
DB00098	Antithymocyte immunoglobulin (rabbit)	Not Available	Completed	1
DB00074	Basiliximab	Not Available	Terminated	1
DB01008	Busulfan	Not Available	Completed	1
DB01008	Busulfan	Not Available	Withdrawn	1
DB00531	Cyclophosphamide	Not Available	Recruiting	1
DB00531	Cyclophosphamide	Not Available	Terminated	1
DB00091	Cyclosporine	Not Available	Recruiting	1
DB00091	Cyclosporine	Not Available	Terminated	1
DB12500	Fedratinib	Not Available	Available	1
DB00099	Filgrastim	Not Available	Withdrawn	1
DB01073	Fludarabine	Not Available	Completed	1
DB01073	Fludarabine	Not Available	Recruiting	1
DB01073	Fludarabine	Not Available	Terminated	1
DB01005	Hydroxyurea	Not Available	Recruiting	1
DB01042	Melphalan	Not Available	Completed	1
DB11763	Momelotinib	Not Available	Available	1
DB00688	Mycophenolate mofetil	Not Available	Terminated	1
DB12340	Navitoclax	Not Available	Available	1
DB08877	Ruxolitinib	Not Available	Completed	1
DB08877	Ruxolitinib	Not Available	Recruiting	1
DB08877	Ruxolitinib	Not Available	Unknown Status	1
DB08877	Ruxolitinib	Not Available	Withdrawn	1
DB11581	Venetoclax	Not Available	Available	1