Hypothyroidism

Also known as: Hypothyroid / Myxedema / Unspecified hypothyroidism / Thyroid activity decreased / Myxedema NOS / Hypothyreosis

DrugDrug NameDrug Description
DB00451LevothyroxineA synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer.
DB00279LiothyronineA thyroid hormone replacement therapy used to treat hypothyroidism, to suppress TSH, and to help in the diagnosis of hyperthyroidism.
DB09100Thyroid, porcineA naturally-occurring peptide hormone used for the replacement therapy for hypothyroidism of any etiology, treatment for euthyroid goiters, and management of thyroid cancers.
DrugDrug NameTargetType
DB00451LevothyroxineThyroid hormone receptor alphatarget
DB00451LevothyroxineThyroid hormone receptor betatarget
DB00451LevothyroxineCytochrome P450 2C8enzyme
DB00451LevothyroxineTransthyretincarrier
DB00451LevothyroxineSerum albumincarrier
DB00451LevothyroxineThyroxine-binding globulincarrier
DB00451LevothyroxineP-glycoprotein 1transporter
DB00451LevothyroxineMonocarboxylate transporter 8transporter
DB00451LevothyroxineSolute carrier organic anion transporter family member 1C1transporter
DB00451LevothyroxineSolute carrier organic anion transporter family member 1A2transporter
DB00451LevothyroxineSolute carrier organic anion transporter family member 1B1transporter
DB00451LevothyroxineSolute carrier organic anion transporter family member 1B3transporter
DB00451LevothyroxineSolute carrier organic anion transporter family member 4A1transporter
DB00451LevothyroxineLarge neutral amino acids transporter small subunit 1transporter
DB00451LevothyroxineUDP-glucuronosyltransferase 1-1enzyme
DB00451LevothyroxineSolute carrier organic anion transporter family member 2B1transporter
DB00451LevothyroxineIntegrin alpha-Vtarget
DB00451LevothyroxineIntegrin beta-3target
DB00451LevothyroxineP-glycoprotein 1enzyme
DB00279LiothyronineThyroid hormone receptor betatarget
DB00279LiothyronineThyroid hormone receptor alphatarget
DB00279LiothyronineThyroxine-binding globulincarrier
DB00279LiothyronineTransthyretincarrier
DB00279LiothyronineSerum albumincarrier
DB00279LiothyronineP-glycoprotein 1transporter
DB00279LiothyronineSolute carrier family 22 member 8transporter
DB00279LiothyronineMonocarboxylate transporter 10transporter
DB00279LiothyronineSolute carrier organic anion transporter family member 4A1transporter
DB00279LiothyronineSolute carrier organic anion transporter family member 1C1transporter
DB00279LiothyronineSolute carrier organic anion transporter family member 1A2transporter
DB00279LiothyronineSodium/bile acid cotransportertransporter
DB00279LiothyronineSolute carrier organic anion transporter family member 4C1transporter
DB00279LiothyronineSolute carrier organic anion transporter family member 1B3transporter
DB00279LiothyronineSolute carrier organic anion transporter family member 1B1transporter
DB00279LiothyronineLarge neutral amino acids transporter small subunit 1transporter
DB00279LiothyronineProliferating cell nuclear antigentarget
DB00279LiothyronineUDP-glucuronosyltransferase 1-1enzyme
DB09100Thyroid, porcineThyroxine-binding globulincarrier
DB09100Thyroid, porcineSerum albumincarrier
DB09100Thyroid, porcineTransthyretincarrier
DB09100Thyroid, porcineMonocarboxylate transporter 8transporter
DB09100Thyroid, porcineSolute carrier organic anion transporter family member 1C1transporter
DB09100Thyroid, porcineSolute carrier organic anion transporter family member 3A1transporter
DB09100Thyroid, porcineSolute carrier organic anion transporter family member 4A1transporter
DB09100Thyroid, porcineLarge neutral amino acids transporter small subunit 1transporter
DB09100Thyroid, porcineSodium/bile acid cotransportertransporter
DB09100Thyroid, porcineType I iodothyronine deiodinaseenzyme
DB09100Thyroid, porcineType II iodothyronine deiodinaseenzyme
DB09100Thyroid, porcineThyroxine 5-deiodinaseenzyme
DB09100Thyroid, porcineThyroid hormone receptor alphatarget
DB09100Thyroid, porcineThyroid hormone receptor betatarget
DB09100Thyroid, porcineSulfotransferase 1A1enzyme
DB09100Thyroid, porcineSulfotransferase 1A2enzyme
DB09100Thyroid, porcineSulfotransferase 1A3/1A4enzyme
DB09100Thyroid, porcineSulfotransferase family cytosolic 1B member 1enzyme
DB09100Thyroid, porcineSulfotransferase 1C2enzyme
DB09100Thyroid, porcineEstrogen sulfotransferaseenzyme
DrugDrug NamePhaseStatusCount
DB00451Levothyroxine2Active Not Recruiting1
DB00451Levothyroxine2Completed2
DB00279Liothyronine2Completed2
DB09100Thyroid, porcine2Active Not Recruiting1
DB00451Levothyroxine2 / 3Recruiting1
DB00451Levothyroxine2 / 3Unknown Status1
DB00279Liothyronine2 / 3Recruiting1
DB01249Iodixanol4Not Yet Recruiting1
DB01362Iohexol4Not Yet Recruiting1
DB08947Iopamidol4Recruiting1
DB09156Iopromide4Not Yet Recruiting1
DB09134Ioversol4Not Yet Recruiting1
DB00583Levocarnitine4Completed1
DB00451Levothyroxine4Active Not Recruiting2
DB00451Levothyroxine4Completed3
DB00451Levothyroxine4Terminated1
DB00451Levothyroxine4Unknown Status4
DB00017Salmon calcitonin4Completed1
DB00052Somatotropin4Completed1
DB00024Thyrotropin alfa4Completed1
DB00451LevothyroxineNot AvailableCompleted8
DB00451LevothyroxineNot AvailableRecruiting2
DB00451LevothyroxineNot AvailableTerminated2
DB00451LevothyroxineNot AvailableUnknown Status1
DB00279LiothyronineNot AvailableCompleted1
DB00279LiothyronineNot AvailableTerminated1
DB00279LiothyronineNot AvailableUnknown Status1
DB09100Thyroid, porcineNot AvailableUnknown Status1