Rhinitis

Also known as: Coryza / Coryza, Acute / Rhinitis NOS / Rhinitis (disorder) / Nasal irritation

Drug	Drug Name	Drug Description
DB06151	Acetylcysteine	A medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose.
DB11386	Chlorobutanol	No approved therapeutic indications on its own.
DB15881	Clonazoline	Not Annotated
DB13679	Dexchlorpheniramine	A chlorpheniramine enantiomer antihistamine indicated in the treatment of sunburns, insect bites, and allergic reactions of the skin.
DB08801	Dimetindene	A 1st generation selective H1 antagonist used topically as an antipruritic and orally to treat allergies.
DB08979	Fenspiride	An oxazolidinone spiro compound with antispasmodic and bronchodilator effects used in the treatment of ENT and respiratory diseases.
DB00588	Fluticasone propionate	A glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis.
DB00332	Ipratropium	An anticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD).
DB06711	Naphazoline	A sympathomimetic vasoconstrictor used for the symptomatic relief of redness and itching of the eye, and nasal congestion.
DB16618	Niaouli oil	An essential oil used to treat nasal congestion and rhinorrhea.
DB12877	Oxatomide	An antihistamine indicated in the treatment and prevention of allergic symptoms.
DB15956	Terpineol	An ingredient in products that are adjunct in the treatment of upper respiratory tract congestion.
DB06764	Tetryzoline	An alpha-adrenergic agonist used in the temporary symptomatic relief of discomfort and redness of the eyes due to minor irritations, as well as alleviate nasal congestion.
DB06694	Xylometazoline	A direct-acting alpha-adrenergic agonist used for the symptomatic treatment of nasal congestion and minor inflammation due to allergies or colds.

Drug	Drug Name	Target	Type
DB06151	Acetylcysteine	Solute carrier organic anion transporter family member 1B1	transporter
DB06151	Acetylcysteine	NAPQI (N-acetyl-p-benzoquinone imine)	target
DB06151	Acetylcysteine	Solute carrier family 22 member 6	transporter
DB06151	Acetylcysteine	Aminoacylase-1	target
DB06151	Acetylcysteine	Inhibitor of nuclear factor kappa-B kinase subunit alpha	target
DB06151	Acetylcysteine	Inhibitor of nuclear factor kappa-B kinase subunit beta	target
DB06151	Acetylcysteine	Glutathione synthetase	target
DB06151	Acetylcysteine	Cystine/glutamate transporter	target
DB06151	Acetylcysteine	Glutamate receptor ionotropic, NMDA 2B	target
DB06151	Acetylcysteine	Glutamate receptor ionotropic, NMDA 1	target
DB06151	Acetylcysteine	Glutamate receptor ionotropic, NMDA 2A	target
DB06151	Acetylcysteine	Glutamate receptor ionotropic, NMDA 2D	target
DB06151	Acetylcysteine	Glutamate receptor ionotropic, NMDA 3A	target
DB06151	Acetylcysteine	Serum albumin	carrier
DB06151	Acetylcysteine	Aminoacylase-1	enzyme
DB11386	Chlorobutanol	Potassium voltage-gated channel subfamily H member 2	target
DB13679	Dexchlorpheniramine	Cytochrome P450 2D6	enzyme
DB08801	Dimetindene	Muscarinic acetylcholine receptor M2	target
DB08801	Dimetindene	Histamine H1 receptor	target
DB00588	Fluticasone propionate	Corticosteroid-binding globulin	carrier
DB00588	Fluticasone propionate	Cytosolic phospholipase A2	target
DB00588	Fluticasone propionate	Glucocorticoid receptor	target
DB00588	Fluticasone propionate	Cytochrome P450 3A4	enzyme
DB00588	Fluticasone propionate	Progesterone receptor	target
DB00588	Fluticasone propionate	Mineralocorticoid receptor	target
DB00588	Fluticasone propionate	Cytochrome P450 3A5	enzyme
DB00588	Fluticasone propionate	Cytochrome P450 3A7	enzyme
DB00588	Fluticasone propionate	Cytochrome P450 2C8	enzyme
DB00588	Fluticasone propionate	Solute carrier organic anion transporter family member 1B1	carrier
DB00588	Fluticasone propionate	P-glycoprotein 1	transporter
DB00588	Fluticasone propionate	Solute carrier organic anion transporter family member 1B1	transporter
DB00332	Ipratropium	Muscarinic acetylcholine receptor M1	target
DB00332	Ipratropium	Muscarinic acetylcholine receptor M2	target
DB00332	Ipratropium	Muscarinic acetylcholine receptor M3	target
DB00332	Ipratropium	Solute carrier family 22 member 5	transporter
DB00332	Ipratropium	Solute carrier family 22 member 4	transporter
DB00332	Ipratropium	Serum albumin	carrier
DB00332	Ipratropium	alpha1-acid glycoprotein	carrier
DB06711	Naphazoline	Alpha-1A adrenergic receptor	target
DB06711	Naphazoline	Alpha-2A adrenergic receptor	target
DB06764	Tetryzoline	Alpha-1 adrenergic receptors	target
DB06764	Tetryzoline	Alpha-2 adrenergic receptors	target
DB06694	Xylometazoline	Alpha-2A adrenergic receptor	target
DB06694	Xylometazoline	Alpha-1A adrenergic receptor	target
DB06694	Xylometazoline	Alpha-1B adrenergic receptor	target
DB06694	Xylometazoline	Alpha-1D adrenergic receptor	target
DB06694	Xylometazoline	Alpha-2B adrenergic receptor	target
DB06694	Xylometazoline	Alpha-2C adrenergic receptor	target

Drug	Drug Name	Phase	Status	Count
DB06282	Levocetirizine	1	Completed	2
DB00471	Montelukast	1	Completed	1
DB00388	Phenylephrine	1	Completed	1
DB00852	Pseudoephedrine	1	Completed	1
DB11883	SB-705498	1	Completed	2
DB00936	Salicylic acid	1	Completed	1
DB00468	Quinine	1 / 2	Terminated	1
DB00083	Botulinum toxin type A	2	Completed	1
DB00341	Cetirizine	2	Completed	1
DB06282	Levocetirizine	2	Completed	1
DB00455	Loratadine	2	Completed	1
DB00043	Omalizumab	2	Completed	1
DB00388	Phenylephrine	2	Completed	1
DB11883	SB-705498	2	Completed	4
DB00062	Albumin human	2 / 3	Completed	1
DB01001	Albuterol	3	Completed	2
DB00835	Brompheniramine	3	Completed	1
DB00835	Brompheniramine	3	Withdrawn	1
DB01075	Diphenhydramine	3	Withdrawn	1
DB13785	Dropropizine	3	Withdrawn	1
DB08906	Fluticasone furoate	3	Completed	1
DB00588	Fluticasone propionate	3	Completed	2
DB06282	Levocetirizine	3	Completed	3
DB00455	Loratadine	3	Completed	2
DB00764	Mometasone	3	Completed	1
DB14512	Mometasone furoate	3	Completed	2
DB00768	Olopatadine	3	Completed	2
DB00388	Phenylephrine	3	Completed	1
DB00388	Phenylephrine	3	Withdrawn	1
DB00635	Prednisone	3	Completed	2
DB00852	Pseudoephedrine	3	Completed	2
DB00852	Pseudoephedrine	3	Withdrawn	1
DB00620	Triamcinolone	3	Completed	1
DB00620	Triamcinolone	3	Terminated	1
DB00443	Betamethasone	4	Completed	1
DB01222	Budesonide	4	Completed	1
DB06774	Capsaicin	4	Completed	1
DB00950	Fexofenadine	4	Completed	1
DB00448	Lansoprazole	4	Unknown Status	1
DB06282	Levocetirizine	4	Completed	1
DB00455	Loratadine	4	Completed	2
DB14512	Mometasone furoate	4	Completed	1
DB00471	Montelukast	4	Unknown Status	1
DB06694	Xylometazoline	4	Completed	1
DB11347	Bacillus subtilis	Not Available	Completed	1
DB00967	Desloratadine	Not Available	Completed	3
DB00967	Desloratadine	Not Available	Suspended	1
DB17743	Fecal microbiota	Not Available	Not Yet Recruiting	1
DB13867	Fluticasone	Not Available	Completed	2
DB06282	Levocetirizine	Not Available	Terminated	1
DB14512	Mometasone furoate	Not Available	Suspended	1
DB00994	Neomycin	Not Available	Completed	1
DB00852	Pseudoephedrine	Not Available	Completed	1
DB00163	Vitamin E	Not Available	Terminated	1
DB15745	Washed Microbiota Transplantation	Not Available	Not Yet Recruiting	1
DB06694	Xylometazoline	Not Available	Completed	1