Bronchitis

Also known as: Bronchial Inflammation / Bronchitis: [unspecified (& chest infection)] or [recurrent wheezy] / Bronchitis unspecified (disorder) / Bronchitis NOS / Bronchitis, not specified as acute or chronic / Bronchitis NOS (disorder) / Bronchitis (disorder)

DrugDrug NameDrug Description
DB06767Ammonium chlorideExpectorant in cough syrups. The ammonium ion (NH4+) in the body plays an important role in the maintenance of acid-base balance. The kidney uses ammonium (NH4+) in place of sodium...
DB09019BromhexineA mucolytic drug used to decrease the viscosity of mucus in the airway, enhancing mucus clearance.
DB00835BrompheniramineA histamine H1 antagonist used to treat coughs, upper respiratory symptoms, and nasal congestion associated with allergies and the common cold.
DB01139CefapirinA first generation cephalosporin indicated in the treatment of susceptible bacterial infections.
DB01114ChlorpheniramineA histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies.
DB00766Clavulanic acidA beta lactamase inhibitor used to enhance the effectiveness of beta lactam antibiotics.
DB01407ClenbuterolA decongestant and bronchodilator used in a variety of respiratory conditions.
DB01075DiphenhydramineA H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.
DB05057ErdosteineA mucolytic agent used to treat conditions characterized by pathological mucus such as respiratory tract infections and chronic obstructive pulmonary disease (COPD).
DB16560Ethyl nitriteAn ingredient in cough syrups for symptomatic treatment of cough, cold, bronchitis, and phlegm.
DB08979FenspirideAn oxazolidinone spiro compound with antispasmodic and bronchodilator effects used in the treatment of ENT and respiratory diseases.
DB00874GuaifenesinAn expectorant commonly found in OTC products for the symptomatic relief from congested chests and coughs associated with cold, bronchitis, and/or other breathing illnesses.
DB13293IpecacAn emetic agent used to induce vomiting in poisoning.
DB09285MorniflumateAn NSAID derived from niflumic acid used in the symptomatic treatment of inflammatory conditions of the airways, ENT, and the urogenital and osteoarticular systems.
DB00397PhenylpropanolamineA sympathomimetic that was previously used in nasal decongestants and weight loss products, but has been withdrawn by the FDA due to safety risks and lack of efficacy.
DB11160PhenyltoloxamineA medication used to treat minor aches and pains.
DB00871TerbutalineA beta-2 adrenergic agonist used as a bronchodilator and to prevent premature labor.
DB00277TheophyllineA xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction.
DB01409TiotropiumA long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD).
DrugDrug NameTargetType
DB09019BromhexineTransmembrane protease serine 2target
DB09019BromhexineAngiotensin-converting enzyme 2target
DB09019BromhexineAngiotensin-converting enzyme 2enzyme
DB00835BrompheniramineHistamine H1 receptortarget
DB00835BrompheniramineMuscarinic acetylcholine receptor M1target
DB00835BrompheniramineMuscarinic acetylcholine receptor M2target
DB00835BrompheniramineMuscarinic acetylcholine receptor M3target
DB00835BrompheniramineMuscarinic acetylcholine receptor M4target
DB00835BrompheniramineMuscarinic acetylcholine receptor M5target
DB01139CefapirinPenicillin-binding protein 1Atarget
DB01114ChlorpheniramineHistamine H1 receptortarget
DB01114ChlorpheniramineCytochrome P450 3A4enzyme
DB01114ChlorpheniramineCytochrome P450 2D6enzyme
DB01114ChlorpheniramineSodium-dependent serotonin transportertarget
DB01114ChlorpheniramineSodium-dependent noradrenaline transportertarget
DB01114ChlorpheniramineSodium-dependent dopamine transportertarget
DB01114ChlorpheniramineCytochrome P450 3A5enzyme
DB01114ChlorpheniramineCytochrome P450 3A7enzyme
DB01114ChlorpheniramineSolute carrier family 22 member 2transporter
DB01114ChlorpheniramineSolute carrier family 22 member 1transporter
DB00766Clavulanic acidBacterial beta-lactamase enzymesenzyme
DB00766Clavulanic acidBacterial beta-lactamase enzymestarget
DB00766Clavulanic acidSodium/glucose cotransporter 1transporter
DB01407ClenbuterolBeta-2 adrenergic receptortarget
DB01407ClenbuterolBeta-nerve growth factortarget
DB01407ClenbuterolTumor necrosis factortarget
DB01407ClenbuterolBeta-1 adrenergic receptortarget
DB01407ClenbuterolBeta-3 adrenergic receptortarget
DB01407ClenbuterolCytochrome P450 1A1enzyme
DB01075DiphenhydramineHistamine H1 receptortarget
DB01075DiphenhydramineCytochrome P450 2D6enzyme
DB01075DiphenhydramineCytochrome P450 2C9enzyme
DB01075DiphenhydramineCytochrome P450 2C19enzyme
DB01075DiphenhydramineSolute carrier family 22 member 2transporter
DB01075DiphenhydramineSolute carrier family 22 member 5transporter
DB01075DiphenhydramineProstaglandin G/H synthase 1enzyme
DB01075DiphenhydramineMuscarinic acetylcholine receptor M2target
DB05057ErdosteineAdenosine deaminaseenzyme
DB00874GuaifenesinNMDA receptortarget
DB13293IpecacCytochrome P450 2D6enzyme
DB13293IpecacCytochrome P450 3A4enzyme
DB09285MorniflumateArachidonate 5-lipoxygenasetarget
DB09285MorniflumateProstaglandin G/H synthase 2target
DB09285MorniflumateArachidonate 5-lipoxygenaseenzyme
DB09285MorniflumateProstaglandin G/H synthase 2enzyme
DB09285MorniflumateLeukotriene B4 receptor 1target
DB09285MorniflumateThromboxane A2 receptortarget
DB09285MorniflumateUDP-glucuronosyltransferase 1-9enzyme
DB00397PhenylpropanolamineAmine oxidase [flavin-containing] Aenzyme
DB00397PhenylpropanolamineDopamine D1 receptortarget
DB00397PhenylpropanolamineBeta-1 adrenergic receptortarget
DB00397PhenylpropanolamineBeta-2 adrenergic receptortarget
DB00397PhenylpropanolamineAlpha-2 adrenergic receptorstarget
DB11160PhenyltoloxamineHistamine H1 receptortarget
DB00871TerbutalineBeta-2 adrenergic receptortarget
DB00871TerbutalineCholinesteraseenzyme
DB00871TerbutalineBeta-3 adrenergic receptortarget
DB00871TerbutalineBeta-1 adrenergic receptortarget
DB00871TerbutalineSulfotransferaseenzyme
DB00871TerbutalineUDP-glucuronosyltransferases (UGTs)enzyme
DB00871TerbutalineSolute carrier family 22 member 5transporter
DB00871TerbutalineSolute carrier family 22 member 2transporter
DB00277TheophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB00277TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00277TheophyllineAdenosine receptor A2btarget
DB00277TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB00277TheophyllinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00277TheophyllineAdenosine receptor A1target
DB00277TheophyllineAdenosine receptor A2atarget
DB00277TheophyllineCytochrome P450 1A2enzyme
DB00277TheophyllineAdenosine deaminaseenzyme
DB00277TheophyllineCytochrome P450 2E1enzyme
DB00277TheophyllineCytochrome P450 3A4enzyme
DB00277TheophyllineSolute carrier family 22 member 7transporter
DB00277TheophyllineCytochrome P450 1A1enzyme
DB00277TheophyllineCytochrome P450 1B1enzyme
DB00277TheophyllineCytochrome P450 2D6enzyme
DB00277TheophyllineHistone deacetylase 2target
DB00277TheophyllineCopine-1target
DB00277TheophyllineMinor histocompatibility antigen H13target
DB00277TheophyllineNodal modulator 1target
DB00277TheophyllinePoly [ADP-ribose] polymerase 1target
DB00277TheophyllineProtein RIC-3target
DB00277TheophyllineTubulin monoglycylase TTLL3target
DB01409TiotropiumMuscarinic acetylcholine receptor M3target
DB01409TiotropiumCytochrome P450 2D6enzyme
DB01409TiotropiumCytochrome P450 3A4enzyme
DB01409TiotropiumMuscarinic acetylcholine receptor M1target
DB01409TiotropiumMuscarinic acetylcholine receptor M2target
DB01409TiotropiumSolute carrier family 22 member 5transporter
DB01409TiotropiumSolute carrier family 22 member 4transporter
DB01409TiotropiumMuscarinic acetylcholine receptor M4target
DB01409TiotropiumMuscarinic acetylcholine receptor M5target
DrugDrug NamePhaseStatusCount
DB04339Carbocisteine1Completed1
DB09536Titanium dioxide1Completed1
DB09321Zinc oxide1Completed1
DB13961Fish oil2 / 3Completed1
DB01137Levofloxacin2 / 3Completed1
DB01060Amoxicillin3Completed1
DB01274Arformoterol3Completed1
DB00207Azithromycin3Completed1
DB01211Clarithromycin3Completed1
DB00766Clavulanic acid3Completed1
DB00803Colistin3Unknown Status1
DB00983Formoterol3Completed1
DB01137Levofloxacin3Completed1
DB06612Mepolizumab3Completed1
DB01274Arformoterol4Completed1
DB00874Guaifenesin4Completed1
DB00852Pseudoephedrine4Completed1
DB01409Tiotropium4Completed1
DB00207AzithromycinNot AvailableCompleted1
DB01211ClarithromycinNot AvailableCompleted1
DB00005EtanerceptNot AvailableCompleted1
DB03852EucalyptolNot AvailableNot Yet Recruiting1
DB00874GuaifenesinNot AvailableCompleted2
DB00332IpratropiumNot AvailableCompleted1
DB12510OzoneNot AvailableCompleted1
DB01015SulfamethoxazoleNot AvailableCompleted3
DB00440TrimethoprimNot AvailableCompleted3
DB00558ZanamivirNot AvailableCompleted1