Empyema

Also known as: Empyema NOS / Empyema (morphologic abnormality) / Empyema (disorder)

DrugDrug NameDrug Description
DB00626BacitracinA cyclic polypeptide antibiotic used to prevent wound infections, treat pneumonia and empyema in infants, and to treat skin and eye infections.
DB01053BenzylpenicillinA penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption.
DB00916MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
DrugDrug NameTargetType
DB00626BacitracinAlpha-2-macroglobulintarget
DB00626BacitracinInsulin-degrading enzymetarget
DB00626BacitracinC55-isoprenyl pyrophosphatetarget
DB00626BacitracinBacitracin transport ATP-binding protein BcrAtransporter
DB00626BacitracinBacitracin transport permease protein BCRBtransporter
DB00626BacitracinBacitracin transport permease protein BcrCtransporter
DB01053BenzylpenicillinOrganic cation/carnitine transporter 2transporter
DB01053BenzylpenicillinSolute carrier family 15 member 1transporter
DB01053BenzylpenicillinSolute carrier family 15 member 2transporter
DB01053BenzylpenicillinSolute carrier family 22 member 6transporter
DB01053BenzylpenicillinOrganic anion transporter 3transporter
DB01053BenzylpenicillinSolute carrier family 22 member 4transporter
DB01053BenzylpenicillinSolute carrier family 22 member 11transporter
DB01053BenzylpenicillinSolute carrier organic anion transporter family member 2B1transporter
DB01053BenzylpenicillinSolute carrier organic anion transporter family member 4A1transporter
DB01053BenzylpenicillinSolute carrier organic anion transporter family member 3A1transporter
DB01053BenzylpenicillinSolute carrier organic anion transporter family member 1B1transporter
DB01053BenzylpenicillinPenicillin-binding protein 3target
DB01053BenzylpenicillinOrganic anion transporter 3target
DB01053BenzylpenicillinSolute carrier family 15 member 1target
DB01053BenzylpenicillinSolute carrier family 15 member 2target
DB01053BenzylpenicillinBeta-lactamase TEMenzyme
DB01053BenzylpenicillinAlbumincarrier
DB01053BenzylpenicillinPeptidoglycan synthase FtsItarget
DB01053BenzylpenicillinPenicillin-binding protein 1Atarget
DB01053BenzylpenicillinPenicillin-binding protein 1Btarget
DB01053BenzylpenicillinPenicillin-binding protein 1Ctarget
DB00916MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
DB00916MetronidazoleCytochrome P450 2C9enzyme
DB00916MetronidazoleCytochrome P450 3A4enzyme
DB00916MetronidazoleCytochrome P450 2C8enzyme
DB00916MetronidazoleUDP-glucuronosyltransferase 1A1enzyme
DB00916MetronidazoleAnaerobic bacterial DNAtarget
DB00916MetronidazoleProtozoal DNAtarget
DB00916MetronidazoleATP-dependent translocase ABCB1transporter
DB00916MetronidazoleCytochrome P450 2A6enzyme
DB00916MetronidazoleCytochrome P450 3A5enzyme
DB00916MetronidazoleCytochrome P450 3A7enzyme
DrugDrug NamePhaseStatusCount
DB00013Urokinase1Completed1
DB01234Dexamethasone2Completed1
DB00009Alteplase3Withdrawn1
DB00013Urokinase3Completed1
DB00009Alteplase4Completed1
DB01327Cefazolin4Completed1
DB01190Clindamycin4Completed1
DB00003Dornase alfa4Completed1
DB00009AlteplaseNot AvailableUnknown Status1
DB01060AmoxicillinNot AvailableCompleted1
DB00766Clavulanic acidNot AvailableCompleted1