Fungal skin infection

Also known as: Skin Mycoses / Skin fungal infection / Dermatomycoses / Superficial Mycoses / Skin fungal infection NOS / Mycotic skin infection / Fungal Infection of the dermal / Dermatitis fungoid / Cutaneous fungal disease / Dermal mycosis (disorder) / Fungal dermatitis / Dermatitis fungal / Dermatitis fungal NOS / Fungal dermatitis NOS / Dermatomycosis, unspecified

DrugDrug NameDrug Description
DB09056AmorolfineA morpholine derivative commonly applied as a lacquer for onychomycosis but is also used for superficial dermatomycosis.
DB00394Beclomethasone dipropionateAn inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks.
DB04794BifonazoleAn azole antifungal drug used to treat fungal skin infections, such as dermatomycosis.
DB11326Boric acidNo FDA- or EMA-approved therapeutic indications on its own.
DB01243ChloroxineAn antibacterial agent used for the treatment of dandruff and mild to moderately severe seborrheic dermatitis of the scalp.
DB13306ChlorquinaldolChlorquinaldol was used historically as a topical antiseptic agent for skin infections. It maintains use in European countries as a combination vaginal tablet with promestriene for use in the treatment...
DB01188CiclopiroxA broad-spectrum topical antifungal agent used to treat mild to moderate onychomycosis of fingernails and toenails in immunocompetent patients.
DB04815ClioquinolAn antifungal cream used to treat a variety of fungal infections.
DB00257ClotrimazoleA topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
DB01127EconazoleA topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor.
DB13434FenticonazoleAn imidazole antifungal used to treat a variety of topical fungal infections.
DB14634Fluprednidene acetateA corticosteroid indicated in the treatment of corticosteroid-responsive dermatoses.
DB02703Fusidic acidA topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria.
DB03808HexamidineAn antiseptic drug used for dermatomycoses and superficial bacterial infections alone or in combination with clotrimazole.
DB01167ItraconazoleA triazole antifungal agent used to treat various fungal infections, such as blastomycosis and onychomycosis.
DB01110MiconazoleAn azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.
DB00239OxiconazoleA topical antifungal used to treat a variety of dermatophyte infections.
DB13977Potassium carbonatePotassium carbonate (K2CO3) is a white salt, soluble in water (insoluble in ethanol) which forms a strongly alkaline solution. It can be made as the product of potassium hydroxide's absorbent...
DB00936Salicylic acidAn acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
DB01153SertaconazoleA topical antifungal agent used in the treatment of interdigital tinea pedis in immunocompetent patients.
DB01007TioconazoleAn imidazole antifungal used to treat vulvovaginal candidiasis.
DB00620TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
DrugDrug NameTargetType
DB00394Beclomethasone dipropionateCorticosteroid-binding globulincarrier
DB00394Beclomethasone dipropionateGlucocorticoid receptortarget
DB00394Beclomethasone dipropionateCytochrome P450 3A5enzyme
DB00394Beclomethasone dipropionateCytochrome P450 3A4enzyme
DB00394Beclomethasone dipropionateP-glycoprotein 1transporter
DB00394Beclomethasone dipropionateATP-binding cassette sub-family G member 2transporter
DB00394Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B1transporter
DB00394Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B3transporter
DB04794BifonazoleCytochrome P450 2B6target
DB04794BifonazoleCytochrome P450 51target
DB04794BifonazoleCytochrome P450 19A1enzyme
DB04794BifonazoleCytochrome P450 2E1enzyme
DB04794BifonazoleCytochrome P450 3A4enzyme
DB01188CiclopiroxSodium/potassium-transporting ATPase subunit alpha-1target
DB00257ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
DB00257ClotrimazoleCytochrome P450 2D6enzyme
DB00257ClotrimazoleCytochrome P450 2C8enzyme
DB00257ClotrimazoleCytochrome P450 3A4enzyme
DB00257ClotrimazoleCytochrome P450 2B6enzyme
DB00257ClotrimazoleP-glycoprotein 1transporter
DB00257ClotrimazoleCytochrome P450 2A6enzyme
DB00257ClotrimazoleCytochrome P450 2C9enzyme
DB00257ClotrimazoleCytochrome P450 2E1enzyme
DB00257ClotrimazoleCytochrome P450 3A7enzyme
DB00257ClotrimazoleCytochrome P450 51target
DB00257ClotrimazoleNuclear receptor subfamily 1 group I member 2target
DB00257ClotrimazoleHydroxycarboxylic acid receptor 2target
DB00257ClotrimazoleBile salt export pumptransporter
DB00257ClotrimazoleSolute carrier organic anion transporter family member 1B1transporter
DB00257ClotrimazoleSolute carrier organic anion transporter family member 1B3transporter
DB00257ClotrimazoleErgosteroltarget
DB01127EconazoleCytochrome P450 19A1enzyme
DB01127EconazoleCytochrome P450 2E1enzyme
DB01127EconazoleCytochrome P450 3A4enzyme
DB01127EconazoleCytochrome P450 51target
DB01127EconazoleNuclear receptor subfamily 1 group I member 2target
DB14634Fluprednidene acetateCytochrome P450 3A4enzyme
DB14634Fluprednidene acetateCytochrome P450 3A5enzyme
DB02703Fusidic acidChloramphenicol acetyltransferase 3target
DB02703Fusidic acidChloramphenicol acetyltransferasetarget
DB02703Fusidic acidBile salt export pumptransporter
DB02703Fusidic acidCanalicular multispecific organic anion transporter 1transporter
DB02703Fusidic acidElongation factor Gtarget
DB02703Fusidic acidCytochrome P450 2D6enzyme
DB02703Fusidic acidCytochrome P450 3A4enzyme
DB02703Fusidic acidUDP-glucuronosyltransferase 1-1enzyme
DB02703Fusidic acidATP-binding cassette sub-family G member 2transporter
DB02703Fusidic acidSolute carrier organic anion transporter family member 1B1transporter
DB03808HexamidineHTH-type transcriptional regulator QacRtarget
DB03808HexamidineHTH-type transcriptional regulator QacRtarget
DB01167ItraconazoleCytochrome P450 3A4enzyme
DB01167ItraconazoleCytochrome P450 3A5enzyme
DB01167ItraconazoleCytochrome P450 3A7enzyme
DB01167ItraconazoleCytochrome P450 2B6enzyme
DB01167ItraconazoleP-glycoprotein 1transporter
DB01167ItraconazoleCytochrome P450 1A1enzyme
DB01167ItraconazoleCytochrome P450 2E1enzyme
DB01167ItraconazoleSolute carrier organic anion transporter family member 2B1transporter
DB01167ItraconazoleCytochrome P450 3A Subfamilyenzyme
DB01167ItraconazoleATP-binding cassette sub-family G member 2transporter
DB01167ItraconazoleSerum albumincarrier
DB01167ItraconazoleLanosterol 14-alpha demethylasetarget
DB01110MiconazoleCytochrome P450 2C9enzyme
DB01110MiconazoleCytochrome P450 2D6enzyme
DB01110MiconazoleCytochrome P450 3A4enzyme
DB01110MiconazoleP-glycoprotein 1transporter
DB01110MiconazoleCytochrome P450 51target
DB01110MiconazoleNitric oxide synthase, endothelialtarget
DB01110MiconazoleNitric oxide synthase, inducibletarget
DB01110MiconazoleCytochrome P450 11B1, mitochondrialenzyme
DB01110MiconazoleCytochrome P450 2A6enzyme
DB01110MiconazoleCytochrome P450 2B6enzyme
DB01110MiconazoleCytochrome P450 2C19enzyme
DB01110MiconazoleCytochrome P450 2E1enzyme
DB01110MiconazoleNuclear receptor subfamily 1 group I member 2target
DB01110MiconazoleLanosterol 14-alpha demethylaseenzyme
DB01110MiconazoleCytochrome P450 19A1enzyme
DB01110MiconazoleCalcium-activated potassium channeltarget
DB01110MiconazoleVoltage-gated Potassium Channelstarget
DB01110MiconazoleInward rectifier potassium channeltarget
DB01110MiconazoleVoltage gated L-type calcium channeltarget
DB01110MiconazoleSerum albumincarrier
DB01110MiconazoleCytochrome P450 2C8enzyme
DB00239OxiconazoleCytochrome P450 51target
DB00239OxiconazoleLanosterol synthasetarget
DB00239OxiconazoleCytochrome P450 3A4enzyme
DB00239OxiconazoleCytochrome P450 2C19enzyme
DB00239OxiconazoleNuclear receptor subfamily 1 group I member 2target
DB00936Salicylic acidSerum albumincarrier
DB00936Salicylic acidProstaglandin G/H synthase 1target
DB00936Salicylic acidProstaglandin G/H synthase 2target
DB00936Salicylic acidAldo-keto reductase family 1 member C1target
DB00936Salicylic acidSolute carrier family 22 member 6transporter
DB00936Salicylic acidSolute carrier family 22 member 10transporter
DB00936Salicylic acidSolute carrier family 22 member 8transporter
DB00936Salicylic acidSolute carrier family 22 member 11transporter
DB00936Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
DB00936Salicylic acidMonocarboxylate transporter 1transporter
DB00936Salicylic acidSolute carrier family 22 member 7transporter
DB00936Salicylic acidCytochrome P450 2C9enzyme
DB01153SertaconazoleCytochrome P450 51target
DB01007TioconazoleLanosterol 14-alpha demethylasetarget
DB01007TioconazoleCytochrome P450 19A1enzyme
DB01007TioconazoleCytochrome P450 2C19enzyme
DB01007TioconazoleCytochrome P450 2E1enzyme
DB01007TioconazoleCytochrome P450 3A4enzyme
DB01007TioconazoleCytochrome P450 51target
DB00620TriamcinoloneCorticosteroid-binding globulincarrier
DB00620TriamcinoloneGlucocorticoid receptortarget
DB00620TriamcinoloneCytochrome P450 3A4enzyme
DB00620TriamcinoloneProstaglandin G/H synthase 2enzyme
DB00620TriamcinoloneCholinesteraseenzyme
DB00620TriamcinoloneCytochrome P450 3A5enzyme
DB00620TriamcinoloneCytochrome P450 3A7enzyme
DB00620TriamcinoloneSerum albumincarrier
DrugDrug NamePhaseStatusCount
DB01167Itraconazole1Completed1
DB01188Ciclopirox4Terminated1