Metastases to bone

Also known as: Bone Metastases / Bony secondaries / Bone cancer metastatic / Bony metastases / Osteolytic bone metastases / Metastasis to bone / Secondary malignant neoplasm of bone (disorder) / Secondary malignant neoplasm of bone and bone marrow

Drug	Drug Name	Drug Description
DB06643	Denosumab	A RANK ligand (RANKL) inhibitor used for the management of osteoporosis in patients at high risk for bone fractures.
DB00710	Ibandronate	A bisphosphonate used to treat osteoporosis in postmenopausal women.
DB00399	Zoledronic acid	A bisphosphonate used to treat malignancy associated hypercalcemia, multiple myeloma, and bone metastasis from solid tumors.

Drug	Drug Name	Target	Type
DB06643	Denosumab	Tumor necrosis factor ligand superfamily member 11	target
DB00710	Ibandronate	Farnesyl pyrophosphate synthase	target
DB00710	Ibandronate	Hydroxylapatite	target
DB00710	Ibandronate	Geranylgeranyl pyrophosphate synthase	target
DB00399	Zoledronic acid	Farnesyl pyrophosphate synthase	target
DB00399	Zoledronic acid	Geranylgeranyl pyrophosphate synthase	target
DB00399	Zoledronic acid	Hydroxylapatite	target
DB00399	Zoledronic acid	Multidrug resistance-associated protein 1	transporter

Drug	Drug Name	Phase	Status	Count
DB00470	Dronabinol	0	Completed	1
DB12775	Abituzumab	1	Completed	1
DB06724	Calcium carbonate	1	Withdrawn	1
DB00958	Carboplatin	1	Completed	1
DB15631	Edodekin alfa	1	Completed	1
DB00099	Filgrastim	1	Withdrawn	1
DB01611	Hydroxychloroquine	1	Terminated	1
DB12381	Merestinib	1	Terminated	1
DB15721	Natural Killer Cell	1	Completed	1
DB01229	Paclitaxel	1	Completed	1
DB06809	Plerixafor	1	Withdrawn	1
DB00072	Trastuzumab	1	Completed	1
DB00399	Zoledronic acid	1	Completed	1
DB01254	Dasatinib	1 / 2	Completed	1
DB01248	Docetaxel	1 / 2	Completed	1
DB14928	Lacnotuzumab	1 / 2	Terminated	1
DB08913	Radium Ra 223 dichloride	1 / 2	Completed	1
DB09566	Radium Ra 223 dichloride	1 / 2	Completed	1
DB08913	Radium Ra 223 dichloride	1 / 2	Unknown Status	1
DB09566	Radium Ra 223 dichloride	1 / 2	Unknown Status	1
DB12813	Radium Ra-223	1 / 2	Unknown Status	1
DB00399	Zoledronic acid	1 / 2	Completed	1
DB00062	Albumin human	2	Recruiting	1
DB00630	Alendronic acid	2	Terminated	1
DB01128	Bicalutamide	2	Terminated	1
DB05153	Cabozantinib	2	Completed	1
DB08875	Cabozantinib	2	Completed	1
DB01101	Capecitabine	2	Unknown Status	1
DB00958	Carboplatin	2	Recruiting	1
DB00515	Cisplatin	2	Completed	1
DB06643	Denosumab	2	Active Not Recruiting	1
DB06643	Denosumab	2	Suspended	1
DB00997	Doxorubicin	2	Not Yet Recruiting	1
DB00997	Doxorubicin	2	Recruiting	1
DB11714	Durvalumab	2	Recruiting	1
DB16047	Elraglusib	2	Recruiting	1
DB08899	Enzalutamide	2	Active Not Recruiting	1
DB08899	Enzalutamide	2	Recruiting	1
DB08899	Enzalutamide	2	Suspended	1
DB00813	Fentanyl	2	Terminated	1
DB00441	Gemcitabine	2	Recruiting	1
DB00762	Irinotecan	2	Recruiting	1
DB01026	Ketoconazole	2	Terminated	1
DB01206	Lomustine	2	Recruiting	1
DB14123	Menthol	2	Recruiting	1
DB09035	Nivolumab	2	Active Not Recruiting	1
DB01229	Paclitaxel	2	Recruiting	1
DB08913	Radium Ra 223 dichloride	2	Completed	2
DB06573	Rebimastat	2	Completed	1
DB12403	Samarium	2	Completed	1
DB06688	Sipuleucel-T	2	Completed	1
DB12546	Strontium chloride Sr-89	2	Completed	1
DB00399	Zoledronic acid	2	Recruiting	1
DB00399	Zoledronic acid	2 / 3	Completed	1
DB00316	Acetaminophen	3	Recruiting	1
DB06643	Denosumab	3	Active Not Recruiting	1
DB06643	Denosumab	3	Completed	4
DB06643	Denosumab	3	Recruiting	1
DB06643	Denosumab	3	Unknown Status	1
DB01234	Dexamethasone	3	Completed	1
DB14649	Dexamethasone acetate	3	Completed	1
DB09398	Fluoride ion F-18	3	Completed	1
DB00441	Gemcitabine	3	Terminated	1
DB00956	Hydrocodone	3	Recruiting	1
DB00465	Ketorolac	3	Recruiting	1
DB00295	Morphine	3	Recruiting	1
DB00497	Oxycodone	3	Recruiting	1
DB08913	Radium Ra 223 dichloride	3	Completed	1
DB09566	Radium Ra 223 dichloride	3	Completed	1
DB00399	Zoledronic acid	3	Completed	4
DB00945	Acetylsalicylic acid	4	Enrolling by Invitation	1
DB01225	Enoxaparin	4	Enrolling by Invitation	1
DB09498	Strontium chloride Sr-89	4	Not Yet Recruiting	1
DB00399	Zoledronic acid	4	Completed	1
DB00945	Acetylsalicylic acid	Not Available	Completed	1
DB01225	Enoxaparin	Not Available	Completed	1
DB08913	Radium Ra 223 dichloride	Not Available	Completed	2
DB08913	Radium Ra 223 dichloride	Not Available	Recruiting	1
DB12813	Radium Ra-223	Not Available	Completed	1
DB00243	Ranolazine	Not Available	Completed	1
DB00072	Trastuzumab	Not Available	Completed	1
DB05773	Trastuzumab emtansine	Not Available	Completed	1