Chemotherapy

Also known as: Antineoplastic Treatment / Chemotherapies / Antineoplastic Agents / Chemotherapy NOS / Cancer chemotherapy / Cancer treatment / Anticancer Treatment / Administration of antineoplastic agent (procedure) / Chemotherapy (procedure) / Drug therapy (procedure) / Antineoplastic chemotherapy regimen (regime/therapy) / Antineoplastic chemotherapy regimen (procedure)

DrugDrug NameDrug Description
DB01425AlizaprideA dopamine antagonist used to prevent nausea and vomiting associated with medical procedures, surgeries, and cancer therapies.
DB00437AllopurinolA xanthine oxidase inhibitor used to reduce urinary and serum uric acid concentrations in patients with gout, recurrent calcium oxalate calculi, and various malignancies.
DB08886Asparaginase Erwinia chrysanthemiAn asparagine-specific enzyme used as part of a chemotherapeutic regimen to treat patients with acute lymphoblastic leukemia and lymphoblastic lymphoma.
DB00023Asparaginase Escherichia coliAn asparaginase enzyme from E. coli used as part of treatment regimens for acute lymphoblastic leukemias.
DB16537Bacillus clausiiA probiotic used to restore normal gastrointestinal flora.
DB03127BenzamidineA drug used to treat painful and inflammatory conditions of the oral cavity, such as infections and gingivitis.
DB09375ChymotrypsinA digestive enzyme supplement used as supportive therapy to manage the side effects associated with conventional chemotherapy, radiotherapy, and hormone therapy.
DB01254DasatinibA tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy.
DB00099FilgrastimA form of recombinant human granulocyte colony stimulating factor used to induce the production of granulocytes and lower infection risk after myelosuppressive therapy.
DB00143GlutathioneFor nutritional supplementation, also for treating dietary shortage or imbalance
DB00889GranisetronA 5HT3 antagonist used to treat nausea and vomiting in cancer therapy and postoperatively.
DB00070Hyaluronidase (ovine)A purified form of sheep hyaluronidase enzyme used as an adjunct in subcutaneous rehydration therapy and to increase absorption of other drugs and radiopaque imaging agents.
DB00034Interferon alfa-2aA form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
DB11360Lactobacillus plantarumLactobacillus plantarum is a member of Lactobacillus, or lactic acid bacteria, that it is widely used in the food industry as a microbial starter and probiotic microorganism. It is considered...
DB14967MargetuximabAn Fc-engineered human/mouse chimeric IgG1κ anti-HER2 monoclonal antibody indicated for patients with HER2-positive metastatic breast cancer.
DB00563MethotrexateAn antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
DB09074OlaparibA poly (ADP-ribose) polymerase (PARP) inhibitor used to treat ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer.
DB09330OsimertinibA tyrosine kinase inhibitor used in the treatment of certain types of non-small cell lung carcinoma.
DB09037PembrolizumabA PD-1 blocking antibody used to treat various types of cancer, including metastatic melanoma, non small-cell lung cancer, cervical cancer, head and neck cancer, and Hodgkin's lymphoma.
DB00165PyridoxineA vitamin used to correct vitamin B6 deficiency and to treat nausea during pregnancy.
DB00049RasburicaseA recombinant form of urate-oxidase enzyme used to treat hyperuricemia following chemotherapy for leukemias and non-Hodgkin's lymphoma.
DB00073RituximabA monoclonal anti-CD20 antibody used to treat non-Hodgkin's lymphoma, chronic lymphocytic leukemia, Wegener's granulomatosis, pemphigus vulgaris, and rheumatoid arthritis.
DB09517Sodium ferric gluconate complexAn iron complex used for the treatment of iron deficiency anemia in adult patients and in pediatric patients age 6 years and older with chronic kidney disease receiving hemodialysis who are receiving supplemental epoetin therapy.
DB00364SucralfateA gastro-duodenal protective agent used in the treatment of gastric and duodenal ulcers and to prevent duodenal ulcer recurrence.
DB00444TeniposideA cytotoxic drug used as an adjunct for chemotherapy induction in the treatment of refractory childhood acute lymphoblastic leukemia.
DB00399Zoledronic acidA bisphosphonate used to treat malignancy associated hypercalcemia, multiple myeloma, and bone metastasis from solid tumors.
DrugDrug NameTargetType
DB01425AlizaprideDopamine D2 receptortarget
DB00437AllopurinolXanthine dehydrogenase/oxidasetarget
DB00437AllopurinolSolute carrier family 22 member 8transporter
DB00437AllopurinolSolute carrier family 22 member 7transporter
DB00437AllopurinolAldehyde oxidaseenzyme
DB00437AllopurinolXanthine dehydrogenase/oxidaseenzyme
DB00437AllopurinolATP-binding cassette sub-family G member 2transporter
DB00437AllopurinolSolute carrier family 22 member 2transporter
DB00023Asparaginase Escherichia coliL-asparaginetarget
DB00023Asparaginase Escherichia coliThyroxine-binding globulincarrier
DB03127BenzamidineUrokinase-type plasminogen activatortarget
DB03127BenzamidineTrypsin-1target
DB03127BenzamidineCasein kinase II subunit alphatarget
DB03127BenzamidineKallikrein-6target
DB03127BenzamidineTrypsin-2target
DB03127BenzamidineTrypsin-3target
DB03127BenzamidineCopper transport protein ATOX1target
DB03127BenzamidineEnoyl-CoA delta isomerase 1, mitochondrialtarget
DB03127BenzamidineTrypsintarget
DB03127BenzamidineSuppressor of tumorigenicity 14 proteintarget
DB03127BenzamidineKallikrein-1target
DB01254DasatinibTyrosine-protein kinase ABL1target
DB01254DasatinibAbelson tyrosine-protein kinase 2target
DB01254DasatinibProto-oncogene tyrosine-protein kinase Srctarget
DB01254DasatinibTyrosine-protein kinase Fyntarget
DB01254DasatinibTyrosine-protein kinase Lcktarget
DB01254DasatinibTyrosine-protein kinase Yestarget
DB01254DasatinibMast/stem cell growth factor receptor Kittarget
DB01254DasatinibPlatelet-derived growth factor receptor betatarget
DB01254DasatinibEphrin type-A receptor 2target
DB01254DasatinibSignal transducer and activator of transcription 5Btarget
DB01254DasatinibCytochrome P450 3A4enzyme
DB01254DasatinibP-glycoprotein 1transporter
DB01254DasatinibATP-binding cassette sub-family G member 2transporter
DB01254DasatinibCytochrome P450 1A1enzyme
DB01254DasatinibCytochrome P450 1A2enzyme
DB01254DasatinibCytochrome P450 1B1enzyme
DB01254DasatinibCytochrome P450 3A5enzyme
DB01254DasatinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB01254DasatinibTyrosine-protein kinase BTKtarget
DB01254DasatinibNuclear receptor subfamily 4 group A member 3target
DB01254DasatinibBreakpoint cluster region proteintarget
DB01254DasatinibTyrosine-protein kinase CSKtarget
DB01254DasatinibEphrin type-A receptor 5target
DB01254DasatinibEphrin type-B receptor 4target
DB01254DasatinibTyrosine-protein kinase Fgrtarget
DB01254DasatinibTyrosine-protein kinase FRKtarget
DB01254DasatinibHeat shock cognate 71 kDa proteintarget
DB01254DasatinibTyrosine-protein kinase Lyntarget
DB01254DasatinibMitogen-activated protein kinase kinase kinase MLTtarget
DB01254DasatinibMitogen-activated protein kinase 14target
DB01254DasatinibAmidophosphoribosyltransferasetarget
DB00099FilgrastimGranulocyte colony-stimulating factor receptortarget
DB00099FilgrastimNeutrophil elastaseenzyme
DB00143GlutathioneGlutathione reductase, mitochondrialtarget
DB00143GlutathioneGlutathione synthetasetarget
DB00143GlutathioneGlutathione S-transferase Mu 1target
DB00143GlutathioneGlutathione S-transferase kappa 1target
DB00143GlutathioneGlutathione S-transferase A3target
DB00143GlutathioneGlutathione S-transferase Mu 3target
DB00143GlutathioneGlutathione S-transferase A4target
DB00143GlutathioneGlutathione S-transferase Mu 4target
DB00143GlutathioneGlutathione S-transferase A5target
DB00143GlutathioneGlutathione S-transferase Ptarget
DB00143GlutathioneGlutathione S-transferase omega-1target
DB00143GlutathioneGlutathione peroxidase 1target
DB00143GlutathioneGlutathione peroxidase 2target
DB00143GlutathioneGlutathione S-transferase theta-1target
DB00143GlutathioneMaleylacetoacetate isomerasetarget
DB00143GlutathioneEpididymal secretory glutathione peroxidasetarget
DB00143GlutathioneGlutathione peroxidase 3target
DB00143GlutathioneLactoylglutathione lyasetarget
DB00143GlutathioneLeukotriene C4 synthasetarget
DB00143GlutathioneMicrosomal glutathione S-transferase 3target
DB00143GlutathioneHematopoietic prostaglandin D synthasetarget
DB00143GlutathioneGlutathione S-transferase A1target
DB00143GlutathioneGlutathione S-transferase A2target
DB00143GlutathioneMicrosomal glutathione S-transferase 1target
DB00143GlutathioneS-formylglutathione hydrolasetarget
DB00143GlutathioneGamma-glutamyltranspeptidase 1target
DB00143GlutathioneGlutathione S-transferase Mu 2target
DB00143GlutathioneGlutaredoxin-1target
DB00143GlutathionePhospholipid hydroperoxide glutathione peroxidase, mitochondrialtarget
DB00143GlutathioneGlutathione S-transferase Mu 5target
DB00143GlutathioneGlutathione peroxidase 6target
DB00143GlutathioneHydroxyacylglutathione hydrolase, mitochondrialtarget
DB00143GlutathioneGlutathione peroxidasetarget
DB00143GlutathioneGlutathione peroxidase 7target
DB00143GlutathioneMicrosomal glutathione S-transferase 2target
DB00143GlutathioneGlutathione S-transferase omega-2target
DB00143GlutathioneGlutaredoxin-2, mitochondrialtarget
DB00143GlutathioneGlutathione S-transferase A2enzyme
DB00143GlutathioneGlutathione S-transferase A1enzyme
DB00143GlutathioneMultidrug resistance-associated protein 1transporter
DB00143GlutathioneCanalicular multispecific organic anion transporter 1transporter
DB00143GlutathioneCanalicular multispecific organic anion transporter 2transporter
DB00143GlutathioneMultidrug resistance-associated protein 4transporter
DB00143GlutathioneMultidrug resistance-associated protein 5transporter
DB00143GlutathioneAldose reductasetarget
DB00143GlutathioneMatrix metalloproteinase-9target
DB00143GlutathioneCytochrome P450 3A4target
DB00143GlutathioneGlutathione peroxidasetarget
DB00889Granisetron5-hydroxytryptamine receptor 3Atarget
DB00889GranisetronCytochrome P450 3A4enzyme
DB00889GranisetronCytochrome P450 1A1enzyme
DB00070Hyaluronidase (ovine)Transforming growth factor beta-1target
DB00070Hyaluronidase (ovine)Serum albumincarrier
DB00070Hyaluronidase (ovine)Hyaluronantarget
DB00034Interferon alfa-2aInterferon alpha/beta receptor 1target
DB00034Interferon alfa-2aInterferon alpha/beta receptor 2target
DB00034Interferon alfa-2aCytochrome P450 1A2enzyme
DB14967MargetuximabReceptor tyrosine-protein kinase erbB-2target
DB00563MethotrexateDihydrofolate reductasetarget
DB00563MethotrexateAldehyde oxidaseenzyme
DB00563MethotrexateMethylenetetrahydrofolate reductaseenzyme
DB00563MethotrexateSerum albumincarrier
DB00563MethotrexateCanalicular multispecific organic anion transporter 2transporter
DB00563MethotrexateMultidrug resistance-associated protein 4transporter
DB00563MethotrexateMultidrug resistance-associated protein 1transporter
DB00563MethotrexateSolute carrier family 22 member 6transporter
DB00563MethotrexateMultidrug resistance-associated protein 7transporter
DB00563MethotrexateSolute carrier family 22 member 8transporter
DB00563MethotrexateCanalicular multispecific organic anion transporter 1transporter
DB00563MethotrexateP-glycoprotein 1transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1A2transporter
DB00563MethotrexateMonocarboxylate transporter 1transporter
DB00563MethotrexateATP-binding cassette sub-family C member 11transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1B3transporter
DB00563MethotrexateSolute carrier family 22 member 11transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1C1transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 3A1transporter
DB00563MethotrexateATP-binding cassette sub-family G member 2transporter
DB00563MethotrexateSolute carrier family 22 member 7transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1B1transporter
DB00563Methotrexate6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00563MethotrexateProton-coupled folate transportertransporter
DB00563MethotrexateFolylpolyglutamate synthase, mitochondrialenzyme
DB00563MethotrexateGamma-glutamyl hydrolaseenzyme
DB00563MethotrexateDihydrofolate reductaseenzyme
DB00563MethotrexateThymidylate synthaseenzyme
DB00563MethotrexateBifunctional purine biosynthesis protein PURHenzyme
DB00563MethotrexateSolute carrier organic anion transporter family member 4C1transporter
DB00563MethotrexateFolate transporter 1transporter
DB00563MethotrexateFolate receptor alphatransporter
DB00563MethotrexateCytochrome P450 3A4enzyme
DB00563MethotrexateThymidylate synthasetarget
DB00563MethotrexateBifunctional purine biosynthesis protein PURHtarget
DB00563MethotrexateFolate receptor betatransporter
DB00563MethotrexateSolute carrier family 15 member 1transporter
DB00563MethotrexateProton-coupled amino acid transporter 1transporter
DB00563MethotrexateCarboxypeptidase G2enzyme
DB09074OlaparibPoly [ADP-ribose] polymerase 1target
DB09074OlaparibCytochrome P450 3A4enzyme
DB09074OlaparibCytochrome P450 2B6enzyme
DB09074OlaparibPoly [ADP-ribose] polymerase 2target
DB09074OlaparibPoly [ADP-ribose] polymerase 3target
DB09074OlaparibCytochrome P450 3A5enzyme
DB09074OlaparibP-glycoprotein 1transporter
DB09074OlaparibATP-binding cassette sub-family G member 2transporter
DB09074OlaparibAldo-keto reductase family 1 member C3target
DB09074OlaparibUDP-glucuronosyltransferase 1-1enzyme
DB09074OlaparibSerum albumincarrier
DB09074OlaparibAlpha-1-acid glycoprotein 1carrier
DB09330OsimertinibEpidermal growth factor receptortarget
DB09330OsimertinibP-glycoprotein 1transporter
DB09330OsimertinibATP-binding cassette sub-family G member 2transporter
DB09330OsimertinibCytochrome P450 3A4enzyme
DB09330OsimertinibCytochrome P450 1A2enzyme
DB09037PembrolizumabProgrammed cell death protein 1target
DB09037PembrolizumabProgrammed cell death 1 ligand 1target
DB00165PyridoxinePyridoxal kinasetarget
DB00165PyridoxineCytochrome P450 1A1enzyme
DB00165PyridoxineSerum albumincarrier
DB00165PyridoxinePyridoxal kinaseenzyme
DB00165PyridoxinePyridoxal phosphate phosphataseenzyme
DB00165PyridoxineAlkaline phosphatase, tissue-nonspecific isozymetransporter
DB00165PyridoxineAlkaline phosphatase, tissue-nonspecific isozymeenzyme
DB00049RasburicaseUric acidtarget
DB00073RituximabB-lymphocyte antigen CD20target
DB09517Sodium ferric gluconate complexFerritin light chaintarget
DB09517Sodium ferric gluconate complexHemoglobin subunit alphatarget
DB09517Sodium ferric gluconate complexHemoglobin subunit betatarget
DB00364SucralfateFibrinogentarget
DB00364SucralfatePepsin A-5target
DB00364SucralfatePro-epidermal growth factortarget
DB00364SucralfateFibroblast growth factor 2target
DB00444TeniposideDNA topoisomerase 2-alphatarget
DB00444TeniposideCytochrome P450 2C19enzyme
DB00444TeniposideCytochrome P450 2C9enzyme
DB00444TeniposideCytochrome P450 3A4enzyme
DB00444TeniposideMultidrug resistance-associated protein 6transporter
DB00444TeniposideATP-binding cassette sub-family G member 2transporter
DB00444TeniposideCytochrome P450 3A5enzyme
DB00399Zoledronic acidFarnesyl pyrophosphate synthasetarget
DB00399Zoledronic acidGeranylgeranyl pyrophosphate synthasetarget
DB00399Zoledronic acidHydroxylapatitetarget
DB00399Zoledronic acidMultidrug resistance-associated protein 1transporter
DrugDrug NamePhaseStatusCount
DB16087Alflutinib1Recruiting1
DB15722CYNK-0011Active Not Recruiting1
DB00762Irinotecan1Completed1
DB11885Anlotinib1 / 2Recruiting1
DB01101Capecitabine1 / 2Unknown Status1
DB00958Carboplatin1 / 2Recruiting1
DB09257Gimeracil1 / 2Not Yet Recruiting1
DB09330Osimertinib1 / 2Recruiting2
DB03209Oteracil1 / 2Not Yet Recruiting1
DB09037Pembrolizumab1 / 2Not Yet Recruiting1
DB00642Pemetrexed1 / 2Recruiting1
DB09256Tegafur1 / 2Not Yet Recruiting1
DB14922Tislelizumab1 / 2Recruiting1
DB08916Afatinib2Not Yet Recruiting1
DB00062Albumin human2Completed1
DB00062Albumin human2Recruiting1
DB11885Anlotinib2Completed1
DB11885Anlotinib2Not Yet Recruiting2
DB11885Anlotinib2Recruiting2
DB00673Aprepitant2Terminated1
DB11595Atezolizumab2Terminated1
DB11945Avelumab2Completed1
DB00112Bevacizumab2Recruiting1
DB00112Bevacizumab2Terminated1
DB00112Bevacizumab2Unknown Status1
DB15414CM-43072Not Yet Recruiting1
DB15414CM-43072Recruiting1
DB06772Cabazitaxel2Completed1
DB14776Camrelizumab2Completed1
DB14776Camrelizumab2Recruiting2
DB01101Capecitabine2Recruiting1
DB01101Capecitabine2Terminated1
DB00958Carboplatin2Not Yet Recruiting3
DB00958Carboplatin2Recruiting1
DB00482Celecoxib2Terminated1
DB00515Cisplatin2Not Yet Recruiting2
DB00515Cisplatin2Recruiting1
DB00531Cyclophosphamide2Terminated1
DB01248Docetaxel2Completed1
DB01248Docetaxel2Recruiting1
DB00016Erythropoietin2Completed2
DB01073Fludarabine2Unknown Status1
DB00544Fluorouracil2Not Yet Recruiting1
DB00441Gemcitabine2Not Yet Recruiting2
DB09257Gimeracil2Recruiting1
DB00889Granisetron2Completed1
DB00619Imatinib2Completed1
DB01259Lapatinib2Terminated1
DB00480Lenalidomide2Recruiting1
DB00650Leucovorin2Not Yet Recruiting1
DB06796Mangafodipir2Completed1
DB00563Methotrexate2Terminated1
DB00745Modafinil2Completed1
DB11793Niraparib2Recruiting2
DB09074Olaparib2Recruiting1
DB03209Oteracil2Recruiting1
DB00526Oxaliplatin2Completed1
DB00526Oxaliplatin2Not Yet Recruiting1
DB00526Oxaliplatin2Recruiting1
DB01229Paclitaxel2Completed1
DB01229Paclitaxel2Not Yet Recruiting1
DB01229Paclitaxel2Recruiting3
DB00377Palonosetron2Completed1
DB00282Pamidronic acid2Terminated1
DB00642Pemetrexed2Not Yet Recruiting1
DB00642Pemetrexed2Recruiting1
DB12257Platinum2Recruiting1
DB08901Ponatinib2Not Yet Recruiting1
DB00073Rituximab2Recruiting1
DB14765Rivoceranib2Completed1
DB14765Rivoceranib2Not Yet Recruiting1
DB14765Rivoceranib2Recruiting1
DB15765Sintilimab2Recruiting2
DB00398Sorafenib2Recruiting1
DB09256Tegafur2Recruiting1
DB14922Tislelizumab2Recruiting1
DB01030Topotecan2Terminated1
DB15043Toripalimab2Recruiting1
DB00399Zoledronic acid2Terminated1
DB00062Albumin human2 / 3Recruiting1
DB00515Cisplatin2 / 3Not Yet Recruiting1
DB00515Cisplatin2 / 3Recruiting1
DB00531Cyclophosphamide2 / 3Unknown Status2
DB01248Docetaxel2 / 3Recruiting1
DB01248Docetaxel2 / 3Unknown Status2
DB00997Doxorubicin2 / 3Unknown Status1
DB00445Epirubicin2 / 3Unknown Status2
DB00544Fluorouracil2 / 3Completed1
DB00544Fluorouracil2 / 3Not Yet Recruiting1
DB00544Fluorouracil2 / 3Recruiting1
DB00441Gemcitabine2 / 3Not Yet Recruiting1
DB00014Goserelin2 / 3Unknown Status1
DB00762Irinotecan2 / 3Completed1
DB01006Letrozole2 / 3Unknown Status1
DB00650Leucovorin2 / 3Completed1
DB00904Ondansetron2 / 3Recruiting1
DB00526Oxaliplatin2 / 3Completed1
DB01229Paclitaxel2 / 3Recruiting1
DB00377Palonosetron2 / 3Recruiting1
DB12257Platinum2 / 3Not Yet Recruiting1
DB00675Tamoxifen2 / 3Unknown Status1
DB15043Toripalimab2 / 3Not Yet Recruiting1
DB15043Toripalimab2 / 3Recruiting1
DB12001Abemaciclib3Recruiting1
DB05812Abiraterone3Recruiting1
DB14776Camrelizumab3Recruiting1
DB00002Cetuximab3Completed1
DB01248Docetaxel3Completed1
DB00445Epirubicin3Completed1
DB00016Erythropoietin3Completed1
DB00544Fluorouracil3Completed2
DB11242Gelatin3Unknown Status1
DB00159Icosapent3Unknown Status1
DB00762Irinotecan3Completed2
DB00650Leucovorin3Completed2
DB09330Osimertinib3Active Not Recruiting1
DB00526Oxaliplatin3Completed1
DB00019Pegfilgrastim3Completed1
DB12257Platinum3Active Not Recruiting1
DB00860Prednisolone3Recruiting1
DB00635Prednisone3Recruiting1
DB00853Temozolomide3Recruiting1
DB14922Tislelizumab3Not Yet Recruiting1
DB14922Tislelizumab3Recruiting1
DB15043Toripalimab3Recruiting1
DB00012Darbepoetin alfa4Completed1
DB00016Erythropoietin4Completed2
DB00016Erythropoietin4Terminated1
DB00987CytarabineNot AvailableRecruiting1
DB01248DocetaxelNot AvailableRecruiting1
DB00650LeucovorinNot AvailableActive Not Recruiting1
DB00650LeucovorinNot AvailableRecruiting1
DB01204MitoxantroneNot AvailableRecruiting1
DB00526OxaliplatinNot AvailableRecruiting1
DB00675TamoxifenNot AvailableCompleted1