Advanced dopaminomimetic psychosis

Also known as: Drug-induced psychosis / Psychoses, Drug / Psychotic disorder caused by drug (disorder) / Substance-induced psychotic disorder

Drugs
Drugs and Targets

Drug	Drug Name	Drug Description
DB00363	Clozapine	An atypical or second-generation antipsychotic drug used in treatment-resistant schizophrenia and to decrease suicide risk in schizophrenic patients.

Drug	Drug Name	Target	Type
DB00363	Clozapine	Dopamine D4 receptor	target
DB00363	Clozapine	Histamine H1 receptor	target
DB00363	Clozapine	Dopamine D2 receptor	target
DB00363	Clozapine	Neuron-specific vesicular protein calcyon	target
DB00363	Clozapine	Histamine H4 receptor	target
DB00363	Clozapine	5-hydroxytryptamine receptor 2A	target
DB00363	Clozapine	5-hydroxytryptamine receptor 1A	target
DB00363	Clozapine	5-hydroxytryptamine receptor 2C	target
DB00363	Clozapine	Dopamine D1 receptor	target
DB00363	Clozapine	Cytochrome P450 1A2	enzyme
DB00363	Clozapine	Cytochrome P450 2D6	enzyme
DB00363	Clozapine	Dopamine D3 receptor	target
DB00363	Clozapine	Muscarinic acetylcholine receptor M1	target
DB00363	Clozapine	Muscarinic acetylcholine receptor M2	target
DB00363	Clozapine	Muscarinic acetylcholine receptor M3	target
DB00363	Clozapine	Muscarinic acetylcholine receptor M4	target
DB00363	Clozapine	Muscarinic acetylcholine receptor M5	target
DB00363	Clozapine	5-hydroxytryptamine receptor 1B	target
DB00363	Clozapine	5-hydroxytryptamine receptor 1D	target
DB00363	Clozapine	5-hydroxytryptamine receptor 1E	target
DB00363	Clozapine	5-hydroxytryptamine receptor 3A	target
DB00363	Clozapine	5-hydroxytryptamine receptor 6	target
DB00363	Clozapine	5-hydroxytryptamine receptor 7	target
DB00363	Clozapine	Alpha-1A adrenergic receptor	target
DB00363	Clozapine	Alpha-1B adrenergic receptor	target
DB00363	Clozapine	Alpha-2A adrenergic receptor	target
DB00363	Clozapine	Alpha-2B adrenergic receptor	target
DB00363	Clozapine	Alpha-2C adrenergic receptor	target
DB00363	Clozapine	Cytochrome P450 2C9	enzyme
DB00363	Clozapine	P-glycoprotein 1	transporter
DB00363	Clozapine	Cytochrome P450 3A4	enzyme
DB00363	Clozapine	Cytochrome P450 2C19	enzyme
DB00363	Clozapine	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
DB00363	Clozapine	UDP-glucuronosyltransferase 1-4	enzyme
DB00363	Clozapine	Cytochrome P450 1A1	enzyme
DB00363	Clozapine	Cytochrome P450 2A6	enzyme
DB00363	Clozapine	Cytochrome P450 2C8	enzyme
DB00363	Clozapine	Glutathione S-transferase P	target
DB00363	Clozapine	Alpha-1-acid glycoprotein 1	carrier
DB00363	Clozapine	Serum albumin	carrier
DB00363	Clozapine	Dopamine D5 receptor	target
DB00363	Clozapine	Gamma-aminobutyric acid type B receptor subunit 1	target
DB00363	Clozapine	Gamma-aminobutyric acid type B receptor subunit 2	target
DB00363	Clozapine	Solute carrier family 22 member 1	transporter
DB00363	Clozapine	Solute carrier family 22 member 2	transporter
DB00363	Clozapine	Solute carrier family 22 member 3	transporter
DB00363	Clozapine	Gamma-aminobutyric acid receptor subunit alpha-1	target
DB00363	Clozapine	Gamma-aminobutyric acid receptor subunit beta-1	target
DB00363	Clozapine	Gamma-aminobutyric acid receptor subunit gamma-1	target

Drug	Drug Name	Phase	Status	Count