Prophylaxis of preeclampsia

Also known as: Preeclampsia / Pre Eclampsia / Pre-Eclampsia / Toxemia of pregnancy / Unspecified pre-eclampsia, unspecified trimester / Pre-eclamptic toxaemia / Unspecified pre-eclampsia / Pre-eclampsia toxaemia / Pre-eclampsia toxemia / Proteinuric hypertension of pregnancy / Pre-eclampsia (disorder) / Hypertension of pregnancy (& [pre-eclampsia]) / Severe pre-eclampsia (disorder) / Pre-eclampsia NOS / Pre-eclampsia NOS (disorder) / Toxaemia of pregnancy / Toxemia NOS (disorder) / Toxemia of pregnancy (disorder) / Mild &/or unspecified pre-eclampsia (& [toxaemia NOS]) / Gestosis / Disease of pregnancy (disorder) / Hypertension with albuminuria (disorder)

DrugDrug NameDrug Description
DB00945Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
DB00999HydrochlorothiazideA thiazide diuretic used to treat edema associated with a number of conditions, and hypertension.
DB00653Magnesium sulfateA drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany.
DrugDrug NameTargetType
DB00945Acetylsalicylic acidProstaglandin G/H synthase 1target
DB00945Acetylsalicylic acidProstaglandin G/H synthase 2target
DB00945Acetylsalicylic acidAldo-keto reductase family 1 member C1target
DB00945Acetylsalicylic acidSolute carrier family 22 member 6transporter
DB00945Acetylsalicylic acidP-glycoprotein 1transporter
DB00945Acetylsalicylic acidCytochrome P450 2C19enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C9enzyme
DB00945Acetylsalicylic acid5'-AMP-activated protein kinasetarget
DB00945Acetylsalicylic acidEndothelin-1 receptortarget
DB00945Acetylsalicylic acidCellular tumor antigen p53target
DB00945Acetylsalicylic acid78 kDa glucose-regulated proteintarget
DB00945Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
DB00945Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
DB00945Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
DB00945Acetylsalicylic acidCaspase-1target
DB00945Acetylsalicylic acidCaspase-3target
DB00945Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00945Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
DB00945Acetylsalicylic acidG1/S-specific cyclin-D1target
DB00945Acetylsalicylic acidMyc proto-oncogene proteintarget
DB00945Acetylsalicylic acidProliferating cell nuclear antigentarget
DB00945Acetylsalicylic acidCyclin Atarget
DB00945Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
DB00945Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
DB00945Acetylsalicylic acidSolute carrier family 22 member 8transporter
DB00945Acetylsalicylic acidSialidase-1target
DB00999HydrochlorothiazideSolute carrier family 12 member 3target
DB00999HydrochlorothiazideSolute carrier family 22 member 6transporter
DB00999HydrochlorothiazideCalcium-activated potassium channel subunit alpha-1target
DB00999HydrochlorothiazideSerum albumincarrier
DB00999HydrochlorothiazideSolute carrier family 22 member 11transporter
DB00999HydrochlorothiazideMultidrug resistance-associated protein 4transporter
DB00999HydrochlorothiazideSolute carrier family 22 member 8transporter
DB00653Magnesium sulfateVoltage-dependent L-type calcium channeltarget
DrugDrug NamePhaseStatusCount
DB00335Atenolol0Recruiting1
DB00335Atenolol0Withdrawn1
DB00598Labetalol0Recruiting1
DB00598Labetalol0Withdrawn1
DB01115Nifedipine0Recruiting1
DB01115Nifedipine0Withdrawn1
DB00107Oxytocin0Completed1
DB01399Salsalate0Recruiting1
DB00175Pravastatin1Active Not Recruiting1
DB05794Serelaxin1Suspended1
DB00945Acetylsalicylic acid1 / 2Recruiting1
DB00126Ascorbic acid1 / 2Completed1
DB06755Beta carotene1 / 2Completed1
DB00121Biotin1 / 2Completed1
DB01373Calcium1 / 2Completed1
DB00169Cholecalciferol1 / 2Completed1
DB09129Chromic chloride1 / 2Completed1
DB11134Cupric oxide1 / 2Completed1
DB00115Cyanocobalamin1 / 2Completed1
DB00917Dinoprostone1 / 2Unknown Status1
DB14491Ferrous fumarate1 / 2Completed1
DB00158Folic acid1 / 2Completed1
DB14513Magnesium1 / 2Completed1
DB00653Magnesium sulfate1 / 2Completed1
DB06757Manganese1 / 2Completed1
DB00929Misoprostol1 / 2Unknown Status1
DB02701Nicotinamide1 / 2Completed1
DB01783Pantothenic acid1 / 2Completed1
DB06715Potassium Iodide1 / 2Completed1
DB00165Pyridoxine1 / 2Completed1
DB00140Riboflavin1 / 2Completed1
DB11068Selenic acid1 / 2Completed1
DB14496Sodium molybdate1 / 2Completed1
DB00152Thiamine1 / 2Completed1
DB00162Vitamin A1 / 2Completed1
DB01593Zinc1 / 2Completed1
DB14003alpha-Tocopherol acetate1 / 2Completed1
DB00945Acetylsalicylic acid2Completed1
DB00945Acetylsalicylic acid2Recruiting2
DB00126Ascorbic acid2Completed1
DB01373Calcium2Completed1
DB00482Celecoxib2Withdrawn1
DB00390Digoxin2Completed1
DB00076Digoxin Immune Fab (Ovine)2Completed1
DB01257Eculizumab2Recruiting1
DB01275Hydralazine2Completed1
DB00598Labetalol2Completed1
DB02701Nicotinamide2Completed1
DB00175Pravastatin2Recruiting1
DB01098Rosuvastatin2Not Yet Recruiting1
DB00203Sildenafil2Terminated1
DB00214Torasemide2Completed1
DB00945Acetylsalicylic acid2 / 3Recruiting1
DB00155Citrulline2 / 3Completed1
DB00633Dexmedetomidine2 / 3Completed1
DB00736Esomeprazole2 / 3Completed1
DB01109Heparin2 / 3Unknown Status1
DB00598Labetalol2 / 3Withdrawn1
DB04465Lactose2 / 3Completed1
DB00653Magnesium sulfate2 / 3Withdrawn1
DB00396Progesterone2 / 3Unknown Status1
DB00945Acetylsalicylic acid3Completed3
DB00945Acetylsalicylic acid3Recruiting3
DB00945Acetylsalicylic acid3Terminated1
DB00945Acetylsalicylic acid3Unknown Status1
DB11166Antithrombin Alfa3Completed1
DB11166Antithrombin Alfa3Recruiting1
DB16094Antithrombin gamma3Recruiting1
DB00125Arginine3Completed1
DB00126Ascorbic acid3Completed2
DB01076Atorvastatin3Completed1
DB01373Calcium3Completed1
DB14002D-alpha-Tocopherol acetate3Completed1
DB01225Enoxaparin3Completed2
DB01225Enoxaparin3Not Yet Recruiting1
DB01364Ephedrine3Withdrawn1
DB00736Esomeprazole3Recruiting1
DB00158Folic acid3Completed1
DB00695Furosemide3Recruiting1
DB00999Hydrochlorothiazide3Recruiting1
DB00281Lidocaine3Withdrawn1
DB00653Magnesium sulfate3Completed1
DB00610Metaraminol3Withdrawn1
DB00929Misoprostol3Completed1
DB00622Nicardipine3Terminated1
DB00175Pravastatin3Recruiting1
DB00296Ropivacaine3Completed1
DB12661Urapidil3Terminated1
DB00316Acetaminophen4Completed1
DB00316Acetaminophen4Unknown Status1
DB00945Acetylsalicylic acid4Completed3
DB00945Acetylsalicylic acid4Not Yet Recruiting2
DB00945Acetylsalicylic acid4Recruiting4
DB00945Acetylsalicylic acid4Withdrawn1
DB00207Azithromycin4Unknown Status1
DB01197Captopril4Completed1
DB00575Clonidine4Completed1
DB01364Ephedrine4Terminated1
DB00695Furosemide4Completed1
DB14570Hydroxyprogesterone4Recruiting1
DB01050Ibuprofen4Completed1
DB01050Ibuprofen4Recruiting1
DB01050Ibuprofen4Unknown Status1
DB01020Isosorbide mononitrate4Completed1
DB00598Labetalol4Completed2
DB00598Labetalol4Recruiting1
DB01002Levobupivacaine4Completed1
DB00653Magnesium sulfate4Completed3
DB00653Magnesium sulfate4Terminated1
DB00653Magnesium sulfate4Unknown Status1
DB00968Methyldopa4Completed1
DB00968Methyldopa4Recruiting1
DB00968Methyldopa4Unknown Status2
DB01115Nifedipine4Completed2
DB01115Nifedipine4Recruiting1
DB00388Phenylephrine4Terminated1
DB00899Remifentanil4Unknown Status1
DB14546Sulfate ion4Unknown Status1
DB00945Acetylsalicylic acidNot AvailableCompleted1
DB00945Acetylsalicylic acidNot AvailableRecruiting3
DB00945Acetylsalicylic acidNot AvailableTerminated2
DB00125ArginineNot AvailableCompleted1
DB00297BupivacaineNot AvailableCompleted1
DB00297BupivacaineNot AvailableRecruiting1
DB01373CalciumNot AvailableCompleted1
DB01373CalciumNot AvailableUnknown Status1
DB06779DalteparinNot AvailableTerminated1
DB00055Drotrecogin alfaNot AvailableCompleted1
DB01225EnoxaparinNot AvailableCompleted1
DB01364EphedrineNot AvailableCompleted2
DB01364EphedrineNot AvailableRecruiting1
DB01364EphedrineNot AvailableUnknown Status1
DB00736EsomeprazoleNot AvailableRecruiting2
DB00813FentanylNot AvailableCompleted1
DB00813FentanylNot AvailableRecruiting1
DB06215FerumoxytolNot AvailableActive Not Recruiting1
DB06789Hydroxyprogesterone caproateNot AvailableWithdrawn1
DB01029IrbesartanNot AvailableSuspended1
DB00598LabetalolNot AvailableRecruiting1
DB00722LisinoprilNot AvailableWithdrawn1
DB00653Magnesium sulfateNot AvailableCompleted4
DB00653Magnesium sulfateNot AvailableNot Yet Recruiting1
DB00653Magnesium sulfateNot AvailableRecruiting2
DB00653Magnesium sulfateNot AvailableUnknown Status1
DB00610MetaraminolNot AvailableUnknown Status1
DB00331MetforminNot AvailableNot Yet Recruiting1
DB00331MetforminNot AvailableRecruiting1
DB00968MethyldopaNot AvailableCompleted1
DB00929MisoprostolNot AvailableActive Not Recruiting1
DB00929MisoprostolNot AvailableCompleted1
DB01115NifedipineNot AvailableCompleted1
DB01115NifedipineNot AvailableRecruiting1
DB00393NimodipineNot AvailableCompleted1
DB00107OxytocinNot AvailableActive Not Recruiting1
DB00107OxytocinNot AvailableCompleted2
DB00107OxytocinNot AvailableRecruiting1
DB00388PhenylephrineNot AvailableCompleted1
DB00388PhenylephrineNot AvailableUnknown Status1
DB00396ProgesteroneNot AvailableTerminated1
DB00396ProgesteroneNot AvailableWithdrawn1
DB00203SildenafilNot AvailableRecruiting1
DB00162Vitamin ANot AvailableRecruiting1
DB00163Vitamin ENot AvailableRecruiting1