Refractory Gastrointestinal stromal tumor

Drug	Drug Name	Drug Description
DB04868	Nilotinib	A kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib.

Drug	Drug Name	Target	Type
DB04868	Nilotinib	Tyrosine-protein kinase ABL1	target
DB04868	Nilotinib	Mast/stem cell growth factor receptor Kit	target
DB04868	Nilotinib	Cytochrome P450 2D6	enzyme
DB04868	Nilotinib	Cytochrome P450 2C8	enzyme
DB04868	Nilotinib	Cytochrome P450 2C9	enzyme
DB04868	Nilotinib	Cytochrome P450 3A4	enzyme
DB04868	Nilotinib	P-glycoprotein 1	transporter
DB04868	Nilotinib	ATP-binding cassette sub-family G member 2	transporter
DB04868	Nilotinib	UDP-glucuronosyltransferase 1-1	transporter
DB04868	Nilotinib	Cytochrome P450 2B6	enzyme
DB04868	Nilotinib	Solute carrier organic anion transporter family member 1B1	transporter

Drug	Drug Name	Phase	Status	Count