Parkinsonian Syndromes

Also known as: Parkinsonian Syndrome / Parkinsonian Disorders / Parkinsonism (finding) / Parkinsonism / Parkinsonism (disorder) / Hypokinetic-rigid syndrome

DrugDrug NameDrug Description
DB12153CiticolineAn endogenous intermediate in the formation of phosphatidylcholine from choline which is thought to have neuroprotective effects.
DB00363ClozapineAn antipsychotic drug used in treatment resistant schizophrenia and to decrease suicide risk in schizophrenic patients.
DB01075DiphenhydramineA H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.
DrugDrug NameTargetType
DB12153CiticolineLicC proteintarget
DB00363ClozapineDopamine D4 receptortarget
DB00363ClozapineHistamine H1 receptortarget
DB00363ClozapineDopamine D2 receptortarget
DB00363ClozapineNeuron-specific vesicular protein calcyontarget
DB00363ClozapineHistamine H4 receptortarget
DB00363Clozapine5-hydroxytryptamine receptor 2Atarget
DB00363Clozapine5-hydroxytryptamine receptor 1Atarget
DB00363Clozapine5-hydroxytryptamine receptor 2Ctarget
DB00363ClozapineDopamine D1 receptortarget
DB00363ClozapineCytochrome P450 1A2enzyme
DB00363ClozapineCytochrome P450 2D6enzyme
DB00363ClozapineDopamine D3 receptortarget
DB00363ClozapineMuscarinic acetylcholine receptor M1target
DB00363ClozapineMuscarinic acetylcholine receptor M2target
DB00363ClozapineMuscarinic acetylcholine receptor M3target
DB00363ClozapineMuscarinic acetylcholine receptor M4target
DB00363ClozapineMuscarinic acetylcholine receptor M5target
DB00363Clozapine5-hydroxytryptamine receptor 1Btarget
DB00363Clozapine5-hydroxytryptamine receptor 1Dtarget
DB00363Clozapine5-hydroxytryptamine receptor 1Etarget
DB00363Clozapine5-hydroxytryptamine receptor 3Atarget
DB00363Clozapine5-hydroxytryptamine receptor 6target
DB00363Clozapine5-hydroxytryptamine receptor 7target
DB00363ClozapineAlpha-1A adrenergic receptortarget
DB00363ClozapineAlpha-1B adrenergic receptortarget
DB00363ClozapineAlpha-2A adrenergic receptortarget
DB00363ClozapineAlpha-2B adrenergic receptortarget
DB00363ClozapineAlpha-2C adrenergic receptortarget
DB00363ClozapineCytochrome P450 2C9enzyme
DB00363ClozapineP-glycoprotein 1transporter
DB00363ClozapineCytochrome P450 3A4enzyme
DB00363ClozapineCytochrome P450 2C19enzyme
DB00363ClozapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00363ClozapineUDP-glucuronosyltransferase 1-4enzyme
DB00363ClozapineCytochrome P450 1A1enzyme
DB00363ClozapineCytochrome P450 2A6enzyme
DB00363ClozapineCytochrome P450 2C8enzyme
DB00363ClozapineGlutathione S-transferase Ptarget
DB01075DiphenhydramineHistamine H1 receptortarget
DB01075DiphenhydramineCytochrome P450 2D6enzyme
DB01075DiphenhydramineCytochrome P450 2C9enzyme
DB01075DiphenhydramineCytochrome P450 2C19enzyme
DB01075DiphenhydramineSolute carrier family 22 member 2transporter
DB01075DiphenhydramineSolute carrier family 22 member 5transporter
DB01075DiphenhydramineProstaglandin G/H synthase 1enzyme
DB01075DiphenhydramineMuscarinic acetylcholine receptor M2target
DrugDrug NamePhaseStatusCount
DB01235Levodopa2Completed1
DB13004Mavoglurant2Completed3
DB00413Pramipexole2Completed1
DB11864Preladenant2Terminated1
DB04947Altropane3Unknown Status1
DB08824Ioflupane I-1233Completed1
DB15823Lactobacillus acidophilus4Recruiting1
DB16540Lactobacillus delbrueckii bulgaricus4Recruiting1
DB00915AmantadineNot AvailableActive Not Recruiting1
DB00248CabergolineNot AvailableCompleted1
DB00190CarbidopaNot AvailableActive Not Recruiting1
DB00190CarbidopaNot AvailableCompleted1
DB00494EntacaponeNot AvailableActive Not Recruiting1
DB01235LevodopaNot AvailableActive Not Recruiting1
DB01235LevodopaNot AvailableCompleted1
DB00413PramipexoleNot AvailableActive Not Recruiting1
DB00268RopiniroleNot AvailableActive Not Recruiting1
DB00323TolcaponeNot AvailableActive Not Recruiting1