Severe Restless Legs Syndrome

Also known as: Severe restless leg syndrome / Severe restless legs syndrome (RLS)

Drug	Drug Name	Drug Description
DB00413	Pramipexole	A non-ergot dopamine agonist used to treat the signs and symptoms of idiopathic Parkinson's disease and Restless Legs Syndrome (RLS).
DB00268	Ropinirole	A non-ergoline dopamine agonist used to treat the symptoms of Parkinson's disease and Restless Legs Syndrome.
DB05271	Rotigotine	A non-selective dopamine agonist used for the treatment of Parkinson's Disease and Restless Leg Syndrome.

Drug	Drug Name	Target	Type
DB00413	Pramipexole	Dopamine D3 receptor	target
DB00413	Pramipexole	Dopamine D4 receptor	target
DB00413	Pramipexole	Dopamine D2 receptor	target
DB00413	Pramipexole	5-hydroxytryptamine receptor 1A	target
DB00413	Pramipexole	Alpha-2A adrenergic receptor	target
DB00413	Pramipexole	Solute carrier family 22 member 2	transporter
DB00413	Pramipexole	Solute carrier family 22 member 1	transporter
DB00413	Pramipexole	Solute carrier family 22 member 3	transporter
DB00268	Ropinirole	Dopamine D2 receptor	target
DB00268	Ropinirole	Dopamine D3 receptor	target
DB00268	Ropinirole	Dopamine D4 receptor	target
DB00268	Ropinirole	Cytochrome P450 1A2	enzyme
DB00268	Ropinirole	Alpha adrenergic receptor	target
DB05271	Rotigotine	Dopamine D3 receptor	target
DB05271	Rotigotine	Dopamine D5 receptor	target
DB05271	Rotigotine	Dopamine D4 receptor	target
DB05271	Rotigotine	Dopamine D2 receptor	target
DB05271	Rotigotine	5-hydroxytryptamine receptor 1A	target
DB05271	Rotigotine	Dopamine D1 receptor	target
DB05271	Rotigotine	Cytochrome P450 2D6	enzyme
DB05271	Rotigotine	Cytochrome P450 3A4	enzyme
DB05271	Rotigotine	Alpha-2B adrenergic receptor	target
DB05271	Rotigotine	Cytochrome P450 2C19	enzyme

Drug	Drug Name	Phase	Status	Count