Varicosities of the great saphenous vein

Also known as: Vein, Varicose / Veins, Varicose / Varicose Veins / Varicose Vein / Asymptomatic varicose veins of unspecified lower extremity / Vein varicose / Varicose veins NOS / Venous varices / Varicosity / Venous ectasia (morphologic abnormality) / Venous varices (disorder) / Varix (morphologic abnormality)

Drug	Drug Name	Drug Description
DB15907	Escin	An anti-inflammatory and vasoconstrictive agent indicated to treat minor muscle and joint trauma.
DB01109	Heparin	An anticoagulant indicated for thromboprophylaxis and to treat thrombosis associated with a variety of conditions such as pulmonary embolism and atrial fibrillation.
DB06811	Polidocanol	A sclerosing agent used for the treatment of uncomplicated spider veins and uncomplicated reticular veins, all less than 3 mm in diameter, in the lower extremity.
DB13124	Troxerutin	Troxerutin has been used in trials studying the treatment of Chronic Venous Insufficiency.

Drug	Drug Name	Target	Type
DB01109	Heparin	Antithrombin-III	target
DB01109	Heparin	Coagulation factor X	target
DB01109	Heparin	P-selectin	target
DB01109	Heparin	Heparanase	enzyme
DB01109	Heparin	Fibroblast growth factor receptor 4	target
DB01109	Heparin	Fibroblast growth factor 4	target
DB01109	Heparin	Fibroblast growth factor 19	target
DB01109	Heparin	Fibroblast growth factor receptor 1	target
DB01109	Heparin	Fibroblast growth factor 1	target
DB01109	Heparin	Fibroblast growth factor receptor 2	target
DB01109	Heparin	Fibroblast growth factor 2	target
DB01109	Heparin	Platelet factor 4	target
DB01109	Heparin	Hepatocyte growth factor	target

Drug	Drug Name	Phase	Status	Count
DB06811	Polidocanol	1	Completed	1
DB11955	Avotermin	2	Completed	1
DB15786	Maritime pine extract	2	Unknown Status	1
DB06811	Polidocanol	2	Completed	2
DB06811	Polidocanol	2 / 3	Completed	1
DB16564	Mucopolysaccharide polysulphate	3	Withdrawn	2
DB06811	Polidocanol	3	Completed	2
DB06812	Povidone-iodine	3	Terminated	1
DB06605	Apixaban	4	Recruiting	1
DB06695	Dabigatran etexilate	4	Recruiting	1
DB06779	Dalteparin	4	Recruiting	1
DB09341	Dextrose, unspecified form	4	Completed	2
DB01225	Enoxaparin	4	Recruiting	1
DB00668	Epinephrine	4	Completed	2
DB00281	Lidocaine	4	Completed	1
DB00961	Mepivacaine	4	Completed	1
DB06811	Polidocanol	4	Completed	3
DB06811	Polidocanol	4	Recruiting	1
DB06811	Polidocanol	4	Withdrawn	1
DB06228	Rivaroxaban	4	Recruiting	1
DB01390	Sodium bicarbonate	4	Completed	2
DB00464	Sodium tetradecyl sulfate	4	Completed	1
DB11328	Tetradecyl hydrogen sulfate (ester)	4	Completed	1
DB06822	Tinzaparin	4	Recruiting	1
DB08995	Diosmin	Not Available	Completed	1
DB00668	Epinephrine	Not Available	Active Not Recruiting	1
DB04703	Hesperidin	Not Available	Completed	1
DB01002	Levobupivacaine	Not Available	Active Not Recruiting	1
DB00281	Lidocaine	Not Available	Active Not Recruiting	1
DB06811	Polidocanol	Not Available	Completed	1
DB06811	Polidocanol	Not Available	Terminated	1
DB00818	Propofol	Not Available	Terminated	1
DB01236	Sevoflurane	Not Available	Terminated	1
DB00464	Sodium tetradecyl sulfate	Not Available	Completed	1
DB00464	Sodium tetradecyl sulfate	Not Available	Terminated	1
DB09099	Somatostatin	Not Available	Completed	1