Postmenopausal

Also known as: Post-menopausal Period / Post-Menopause / Post Menopausal / Post-menopausal Status / Postmenopause / Post-Menopausal / Postmenopausal Period / Postmenopausal state (finding)

DrugDrug NameDrug Description
DB05084AbaloparatideA parathyroid hormone-related protein (PTHrP) analog used for the treatment of osteoporosis in postmenopausal women with a high risk of fracture.
DB00630Alendronic acidA bisphosphonate drug that prevents osteoclastic bone resorption which is used for the prevention and treatment of osteoporosis.
DB06643DenosumabA RANK ligand (RANKL) inhibitor used for the management of osteoporosis in patients at high risk for bone fractures.
DB00783EstradiolAn estrogenic steroid used to treat vasomotor symptoms of vulvar and vaginal atrophy in menopause, hypoestrogenism, prevention of postmenopausal osteoporosis, treatment of breast cancer, and advanced androgen-dependent carcinoma of the prostate.
DB00990ExemestaneAn aromatase inhibitor used to treat breast cancer in postmenopausal women after treatment with tamoxifen.
DB01259LapatinibAn antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-negative breast cancer in patients who received prior chemotherapeutic treatments.
DB01006LetrozoleAn aromatase inhibitor used to treat breast cancer in postmenopausal women.
DB00281LidocaineA local anesthetic used in a wide variety of superficial and invasive procedures.
DB09073PalbociclibAn endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer.
DB00396ProgesteroneA hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia.
DB11730RibociclibA kinase inhibitor used to treat HR+, HER2- advanced or metastatic breast cancer.
DB00884Risedronic acidA bisphosphonate used to treat osteoporosis and Paget's disease.
DB11866RomosozumabA monoclonal antibody used to treat osteoporosis in postmenopausal women at high risk of fracture, patients who are intolerant of other treatments, or patients who have failed other treatments.
DB00017Salmon calcitoninA synthetic peptide form of calcitonin used to inhibit bone resorption in the treatment of hypercalcemia, osteoporosis, and Paget's disease.
DB00539ToremifeneA first generation nonsteroidal selective estrogen receptor modulator used to treat certain breast cancers.
DB00285VenlafaxineA selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression.
DrugDrug NameTargetType
DB05084AbaloparatideParathyroid hormone/parathyroid hormone-related peptide receptortarget
DB00630Alendronic acidFarnesyl pyrophosphate synthasetarget
DB00630Alendronic acidTyrosine-protein phosphatase non-receptor type 4target
DB00630Alendronic acidReceptor-type tyrosine-protein phosphatase Starget
DB00630Alendronic acidReceptor-type tyrosine-protein phosphatase epsilontarget
DB00630Alendronic acidV-type proton ATPase catalytic subunit Atarget
DB00630Alendronic acidHydroxylapatitetarget
DB06643DenosumabTumor necrosis factor ligand superfamily member 11target
DB00783EstradiolEstrogen receptor alphatarget
DB00783EstradiolNuclear receptor subfamily 1 group I member 2target
DB00783EstradiolSex hormone-binding globulincarrier
DB00783EstradiolEstrogen receptor betatarget
DB00783EstradiolCytochrome P450 1A2enzyme
DB00783EstradiolUDP-glucuronosyltransferase 1-1enzyme
DB00783EstradiolSerum albumincarrier
DB00783EstradiolFatty acid-binding protein, intestinalcarrier
DB00783EstradiolCytochrome P450 3A4enzyme
DB00783EstradiolCytochrome P450 3A5enzyme
DB00783EstradiolCytochrome P450 3A7enzyme
DB00783EstradiolSolute carrier family 22 member 2transporter
DB00783EstradiolSolute carrier family 22 member 3transporter
DB00783EstradiolMultidrug resistance-associated protein 7transporter
DB00783EstradiolSolute carrier family 22 member 11transporter
DB00783EstradiolATP-binding cassette sub-family G member 2transporter
DB00783EstradiolSolute carrier organic anion transporter family member 1B1transporter
DB00783EstradiolP-glycoprotein 1transporter
DB00783EstradiolCytochrome P450 1A1enzyme
DB00783EstradiolCytochrome P450 1B1enzyme
DB00783EstradiolCytochrome P450 2C19enzyme
DB00783EstradiolCytochrome P450 2C8enzyme
DB00783EstradiolCytochrome P450 2C9enzyme
DB00783EstradiolSolute carrier family 22 member 8transporter
DB00783EstradiolSolute carrier organic anion transporter family member 1B3transporter
DB00783EstradiolSolute carrier organic anion transporter family member 1C1transporter
DB00783EstradiolNeuronal acetylcholine receptor subunit alpha-4target
DB00783EstradiolG-protein coupled estrogen receptor 1target
DB00783EstradiolATP synthase subunit atarget
DB00783EstradiolBeclin-1target
DB00783EstradiolUDP-glucuronosyltransferase 2B15enzyme
DB00783EstradiolCatechol O-methyltransferaseenzyme
DB00783EstradiolUDP-glucuronosyltransferases (UGTs)enzyme
DB00990ExemestaneCytochrome P450 19A1target
DB00990ExemestaneCytochrome P450 3A4enzyme
DB00990ExemestaneCytochrome P450 19A1enzyme
DB01259LapatinibEpidermal growth factor receptortarget
DB01259LapatinibReceptor tyrosine-protein kinase erbB-2target
DB01259LapatinibCytochrome P450 3A4enzyme
DB01259LapatinibCytochrome P450 2C8enzyme
DB01259LapatinibP-glycoprotein 1transporter
DB01259LapatinibAntigen peptide transporter 1transporter
DB01259LapatinibCytochrome P450 3A5enzyme
DB01259LapatinibCytochrome P450 2C19enzyme
DB01006LetrozoleCytochrome P450 19A1target
DB01006LetrozoleCytochrome P450 3A4enzyme
DB01006LetrozoleCytochrome P450 2A6enzyme
DB01006LetrozoleCytochrome P450 19A1enzyme
DB01006LetrozoleCytochrome P450 2C19enzyme
DB01006LetrozoleUDP-glucuronosyltransferase 2B7enzyme
DB01006LetrozoleSerum albumincarrier
DB01006LetrozoleP-glycoprotein 1transporter
DB00281LidocaineSodium channel protein type 5 subunit alphatarget
DB00281LidocaineSodium channel protein type 10 subunit alphatarget
DB00281LidocaineEpidermal growth factor receptortarget
DB00281LidocaineSodium channel protein type 9 subunit alphatarget
DB00281LidocaineCytochrome P450 1A2enzyme
DB00281LidocaineCytochrome P450 2D6enzyme
DB00281LidocaineCytochrome P450 3A4enzyme
DB00281LidocaineCytochrome P450 3A5enzyme
DB00281LidocaineCytochrome P450 3A7enzyme
DB00281LidocaineSolute carrier family 22 member 5transporter
DB00281LidocaineP-glycoprotein 1transporter
DB00281LidocaineCytochrome P450 2A6enzyme
DB00281LidocaineCytochrome P450 2B6enzyme
DB00281LidocaineCytochrome P450 2C8enzyme
DB00281LidocaineCytochrome P450 2C9enzyme
DB00281LidocaineSodium channel protein type 4 subunit alphatarget
DB00281LidocaineAlpha-1-acid glycoprotein 1target
DB00281LidocaineAlpha-1-acid glycoprotein 2target
DB09073PalbociclibCyclin-dependent kinase 4target
DB09073PalbociclibCyclin-dependent kinase 6target
DB09073PalbociclibCytochrome P450 3A4enzyme
DB09073PalbociclibBile salt sulfotransferaseenzyme
DB09073PalbociclibP-glycoprotein 1transporter
DB09073PalbociclibATP-binding cassette sub-family G member 2transporter
DB09073PalbociclibSerum albumincarrier
DB09073PalbociclibSolute carrier family 22 member 1transporter
DB00396ProgesteroneProgesterone receptortarget
DB00396ProgesteroneEstrogen receptor alphatarget
DB00396ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyasetarget
DB00396ProgesteroneCytochrome P450 2C19enzyme
DB00396ProgesteroneCytochrome P450 2C9enzyme
DB00396ProgesteroneCytochrome P450 3A4enzyme
DB00396ProgesteroneCytochrome P450 3A5enzyme
DB00396ProgesteroneCytochrome P450 3A7enzyme
DB00396ProgesteroneP-glycoprotein 1transporter
DB00396ProgesteroneSolute carrier family 22 member 2transporter
DB00396ProgesteroneSolute carrier family 22 member 1transporter
DB00396ProgesteroneSolute carrier family 22 member 3transporter
DB00396ProgesteroneBile salt export pumptransporter
DB00396ProgesteroneMultidrug resistance-associated protein 1transporter
DB00396ProgesteroneSodium/bile acid cotransportertransporter
DB00396ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB00396ProgesteroneCytochrome P450 1A1enzyme
DB00396ProgesteroneCytochrome P450 1B1enzyme
DB00396ProgesteroneCytochrome P450 2A6enzyme
DB00396ProgesteroneCytochrome P450 2D6enzyme
DB00396ProgesteroneMineralocorticoid receptortarget
DB00396ProgesteroneKappa-type opioid receptortarget
DB00396ProgesteroneAlpha-1-acid glycoprotein 1target
DB00396ProgesteroneGlucocorticoid receptortarget
DB00396ProgesteroneAndrogen receptortarget
DB00396ProgesteroneSex hormone-binding globulintarget
DB00396ProgesteroneSolute carrier organic anion transporter family member 1B1transporter
DB00396ProgesteroneATP-binding cassette sub-family G member 2transporter
DB00396ProgesteroneEstrogen receptor betatarget
DB00396ProgesteroneSolute carrier organic anion transporter family member 1B3transporter
DB11730RibociclibCyclin-dependent kinase 4target
DB11730RibociclibCyclin-dependent kinase 6target
DB11730RibociclibCytochrome P450 3A4enzyme
DB00884Risedronic acidFarnesyl pyrophosphate synthasetarget
DB00884Risedronic acidHydroxylapatitetarget
DB00884Risedronic acidProstaglandin G/H synthase 2enzyme
DB11866RomosozumabSclerostintarget
DB00017Salmon calcitoninCalcitonin receptortarget
DB00539ToremifeneEstrogen receptor alphatarget
DB00539ToremifeneCytochrome P450 3A4enzyme
DB00539ToremifeneP-glycoprotein 1transporter
DB00539ToremifeneCytochrome P450 1A1enzyme
DB00539ToremifeneSex hormone-binding globulintarget
DB00285VenlafaxineSodium-dependent serotonin transportertarget
DB00285VenlafaxineSodium-dependent noradrenaline transportertarget
DB00285VenlafaxineCytochrome P450 2D6enzyme
DB00285VenlafaxineCytochrome P450 3A4enzyme
DB00285VenlafaxineSodium-dependent dopamine transportertarget
DB00285VenlafaxineP-glycoprotein 1transporter
DB00285VenlafaxineATP-binding cassette sub-family G member 2transporter
DrugDrug NamePhaseStatusCount
DB06401Bazedoxifene1Completed3
DB00286Conjugated estrogens1Completed7
DB06643Denosumab1Terminated1
DB00783Estradiol1Completed1
DB00005Etanercept1Terminated1
DB01590Everolimus1Completed1
DB01006Letrozole1Completed1
DB00603Medroxyprogesterone acetate1Completed3
DB00884Risedronic acid1Completed1
DB11866Romosozumab1Completed1
DB00624Testosterone1Withdrawn1
DB00072Trastuzumab1Completed1
DB12483Copanlisib1 / 2Active Not Recruiting1
DB00783Estradiol1 / 2Completed1
DB01006Letrozole1 / 2Active Not Recruiting1
DB01006Letrozole1 / 2Recruiting1
DB09073Palbociclib1 / 2Active Not Recruiting1
DB00396Progesterone1 / 2Completed1
DB11730Ribociclib1 / 2Recruiting1
DB00072Trastuzumab1 / 2Recruiting1
DB05812Abiraterone2Completed1
DB05220Alisertib2Active Not Recruiting1
DB14336Angelica sinensis root2Completed1
DB00125Arginine2Completed1
DB06680Asoprisnil2Completed2
DB01076Atorvastatin2Completed1
DB06401Bazedoxifene2Recruiting1
DB13975Black cohosh2Completed1
DB01156Bupropion2Completed1
DB00286Conjugated estrogens2Completed4
DB00286Conjugated estrogens2Recruiting1
DB01395Drospirenone2Completed1
DB00783Estradiol2Completed3
DB00990Exemestane2Completed1
DB00947Fulvestrant2Active Not Recruiting1
DB01645Genistein2Completed1
DB00619Imatinib2Completed1
DB01006Letrozole2Active Not Recruiting1
DB01006Letrozole2Completed1
DB01006Letrozole2Recruiting1
DB01006Letrozole2Unknown Status1
DB00007Leuprolide2Completed1
DB00603Medroxyprogesterone acetate2Completed1
DB00331Metformin2Completed1
DB00107Oxytocin2Completed1
DB09073Palbociclib2Recruiting1
DB09037Pembrolizumab2Recruiting1
DB00860Prednisolone2Completed1
DB00635Prednisone2Completed1
DB11787Ralimetinib2Terminated1
DB00481Raloxifene2Completed1
DB11730Ribociclib2Active Not Recruiting1
DB00884Risedronic acid2Completed1
DB00675Tamoxifen2Terminated1
DB08867Ulipristal2Completed1
DB00783Estradiol2 / 3Completed1
DB00126Ascorbic acid3Completed1
DB06401Bazedoxifene3Completed1
DB06401Bazedoxifene3Recruiting1
DB01373Calcium3Completed1
DB00286Conjugated estrogens3Completed2
DB00286Conjugated estrogens3Recruiting1
DB01395Drospirenone3Completed2
DB00378Dydrogesterone3Completed2
DB00783Estradiol3Completed10
DB12007Isoflavone3Unknown Status1
DB01006Letrozole3Completed1
DB00603Medroxyprogesterone acetate3Completed3
DB00717Norethisterone3Completed1
DB01708Prasterone3Withdrawn1
DB00396Progesterone3Completed3
DB00017Salmon calcitonin3Completed1
DB11094Vitamin D3Completed1
DB00163Vitamin E3Completed1
DB00399Zoledronic acid3Completed1
DB01217Anastrozole4Withdrawn1
DB01395Drospirenone4Completed1
DB00783Estradiol4Completed5
DB00990Exemestane4Withdrawn1
DB01006Letrozole4Withdrawn1
DB00396Progesterone4Completed3
DB00675Tamoxifen4Withdrawn1
DB09070Tibolone4Completed1
DB00539Toremifene4Withdrawn1
DB13129Trimegestone4Completed1
DB01217AnastrozoleNot AvailableCompleted1
DB06401BazedoxifeneNot AvailableTerminated1
DB00286Conjugated estrogensNot AvailableCompleted2
DB01395DrospirenoneNot AvailableCompleted2
DB00783EstradiolNot AvailableCompleted6
DB04573EstriolNot AvailableRecruiting1
DB05829Parathyroid hormoneNot AvailableCompleted1
DB00396ProgesteroneNot AvailableCompleted1
DB00481RaloxifeneNot AvailableTerminated1
DB09321Zinc oxideNot AvailableCompleted1