Acne Rosacea

Also known as: Rosacea / Rosaceas / Rosacea, unspecified

DrugDrug NameDrug Description
DB01380Cortisone acetateA steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones.
DB01234DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
DB00254DoxycyclineA tetracycline antibiotic used to treat a wide variety of bacterial infections.
DB00982IsotretinoinA retinoid used to treat severe recalcitrant acne.
DB00602IvermectinAn anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis.
DB00873LoteprednolNot Annotated
DB00959MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
DB00916MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
DB00860PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
DB00759TetracyclineAn antibiotic used to treat a wide variety of susceptible infections.
DrugDrug NameTargetType
DB01380Cortisone acetateGlucocorticoid receptortarget
DB01380Cortisone acetateCytochrome P450 3A4enzyme
DB01380Cortisone acetateCytochrome P450 3A5enzyme
DB01234DexamethasoneGlucocorticoid receptortarget
DB01234DexamethasoneAnnexin A1target
DB01234DexamethasoneNitric oxide synthase, inducibletarget
DB01234DexamethasoneNuclear receptor subfamily 0 group B member 1target
DB01234DexamethasoneCytochrome P450 3A4enzyme
DB01234DexamethasoneCytochrome P450 3A5enzyme
DB01234DexamethasoneCytochrome P450 3A7enzyme
DB01234DexamethasoneBile salt export pumptransporter
DB01234DexamethasoneP-glycoprotein 1transporter
DB01234DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DB01234DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DB01234DexamethasoneATP-binding cassette sub-family G member 2transporter
DB01234DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01234DexamethasoneCytochrome P450 1A1enzyme
DB01234DexamethasoneCytochrome P450 2A6enzyme
DB01234DexamethasoneCytochrome P450 2B6enzyme
DB01234DexamethasoneCytochrome P450 2C19enzyme
DB01234DexamethasoneCytochrome P450 2C8enzyme
DB01234DexamethasoneCytochrome P450 2E1enzyme
DB01234DexamethasoneCytochrome P450 3A43enzyme
DB01234DexamethasoneCytochrome P450 4A11enzyme
DB01234DexamethasoneNuclear receptor subfamily 1 group I member 2target
DB01234DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DB01234DexamethasoneSerum albumincarrier
DB01234DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DB01234DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB01234DexamethasoneSolute carrier family 22 member 8transporter
DB00254Doxycycline16S ribosomal RNAtarget
DB00254DoxycyclineSolute carrier family 22 member 6transporter
DB00254DoxycyclineCytochrome P450 3A4enzyme
DB00254DoxycyclineATP-binding cassette sub-family B member 5transporter
DB00982IsotretinoinRetinoic acid receptor alphatarget
DB00982IsotretinoinSerum albumincarrier
DB00982IsotretinoinRetinoic acid receptor gammatarget
DB00982IsotretinoinCytochrome P450 3A4enzyme
DB00602IvermectinGamma-aminobutyric acid receptor subunit beta-3target
DB00602IvermectinGlycine receptor subunit alpha-3target
DB00602IvermectinP-glycoprotein 1transporter
DB00602IvermectinMultidrug resistance-associated protein 1transporter
DB00602IvermectinCanalicular multispecific organic anion transporter 1transporter
DB00602IvermectinATP-binding cassette sub-family G member 2transporter
DB00602IvermectinCytochrome P450 3A4enzyme
DB00602IvermectinSolute carrier organic anion transporter family member 1B1transporter
DB00602IvermectinSolute carrier organic anion transporter family member 1B3transporter
DB00959MethylprednisoloneGlucocorticoid receptortarget
DB00959MethylprednisoloneCytochrome P450 3A4enzyme
DB00959MethylprednisoloneP-glycoprotein 1transporter
DB00959MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
DB00959MethylprednisoloneCytochrome P450 2A6enzyme
DB00959MethylprednisoloneCytochrome P450 1B1enzyme
DB00959MethylprednisoloneCytochrome P450 2B6enzyme
DB00959MethylprednisoloneCytochrome P450 2C8enzyme
DB00959MethylprednisoloneCytochrome P450 2C9enzyme
DB00959MethylprednisoloneCytochrome P450 2C19enzyme
DB00959MethylprednisoloneAnnexin A1target
DB00959Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
DB00959Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
DB00959MethylprednisoloneSerum albumincarrier
DB00916MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
DB00916MetronidazoleCytochrome P450 2C9enzyme
DB00916MetronidazoleCytochrome P450 3A4enzyme
DB00916MetronidazoleCytochrome P450 2C8enzyme
DB00916MetronidazoleUDP-glucuronosyltransferase 1-1enzyme
DB00916MetronidazoleAnaerobic bacterial DNAtarget
DB00916MetronidazoleProtozoal DNAtarget
DB00916MetronidazoleP-glycoprotein 1transporter
DB00916MetronidazoleCytochrome P450 2A6enzyme
DB00916MetronidazoleCytochrome P450 3A5enzyme
DB00916MetronidazoleCytochrome P450 3A7enzyme
DB00860PrednisoloneCorticosteroid-binding globulincarrier
DB00860PrednisoloneCytochrome P450 3A4enzyme
DB00860PrednisoloneGlucocorticoid receptortarget
DB00860PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
DB00860PrednisoloneP-glycoprotein 1transporter
DB00860PrednisoloneSerum albumincarrier
DB00759Tetracycline16S ribosomal RNAtarget
DB00759TetracyclineMajor prion proteintarget
DB00759TetracyclineSerum albumincarrier
DB00759TetracyclineCytochrome P450 3A4enzyme
DB00759TetracyclineSolute carrier family 22 member 6transporter
DB00759TetracyclineSolute carrier family 22 member 8transporter
DB00759TetracyclineSolute carrier family 22 member 11transporter
DB00759TetracyclineSolute carrier family 22 member 7transporter
DB00759Tetracycline30S ribosomal protein S3target
DB00759Tetracycline30S ribosomal protein S8target
DB00759Tetracycline30S ribosomal protein S19target
DB00759Tetracycline30S ribosomal protein S14target
DB00759Tetracycline30S ribosomal protein S7target
DB00759TetracyclineMultidrug translocase MdfAtarget
DB00759TetracyclineProtein-arginine deiminase type-4target
DB00759TetracyclineSolute carrier organic anion transporter family member 2B1transporter
DrugDrug NamePhaseStatusCount
DB00513Aminocaproic acid0Completed1
DB00254Doxycycline0Active Not Recruiting2
DB00602Ivermectin0Active Not Recruiting1
DB00548Azelaic acid1Completed2
DB00254Doxycycline1Completed1
DB11629Laropiprant1Completed1
DB00916Metronidazole1Completed1
DB00373Timolol1Recruiting1
DB00602Ivermectin1 / 2Completed1
DB00083Botulinum toxin type A2Completed1
DB00250Dapsone2Completed1
DB00254Doxycycline2Completed1
DB14039Erenumab2Recruiting1
DB00602Ivermectin2Not Yet Recruiting1
DB00916Metronidazole2Completed1
DB01017Minocycline2Completed2
DB01017Minocycline2Terminated1
DB12428PAC-140282Completed1
DB01220Rifaximin2Withdrawn1
DB00755Tretinoin2Completed1
DB00548Azelaic acid2 / 3Completed1
DB01190Clindamycin2 / 3Completed1
DB00755Tretinoin2 / 3Completed1
DB00548Azelaic acid3Completed4
DB00484Brimonidine3Completed4
DB00254Doxycycline3Completed2
DB00602Ivermectin3Completed1
DB00602Ivermectin3Unknown Status1
DB06574Omiganan3Completed1
DB06610Omiganan3Completed3
DB00935Oxymetazoline3Completed4
DB00755Tretinoin3Terminated1
DB00855Aminolevulinic acid4Unknown Status1
DB00548Azelaic acid4Completed1
DB12792Boscalid4Completed1
DB00484Brimonidine4Completed4
DB00484Brimonidine4Recruiting1
DB00091Cyclosporine4Completed1
DB00254Doxycycline4Completed5
DB00602Ivermectin4Completed2
DB00916Metronidazole4Completed3
DB00935Oxymetazoline4Completed1
DB12035Sarecycline4Active Not Recruiting1
DB00548Azelaic acidNot AvailableCompleted3
DB00112BevacizumabNot AvailableCompleted1
DB00484BrimonidineNot AvailableCompleted1
DB00254DoxycyclineNot AvailableUnknown Status1
DB04465LactoseNot AvailableTerminated1
DB00916MetronidazoleNot AvailableCompleted2
DB00669SumatriptanNot AvailableCompleted1
DB09322Zinc sulfateNot AvailableTerminated1