Idiopathic Thrombocytopenic Purpura

Also known as: Purpura, Thrombocytopenic, Idiopathic / Immune Thrombocytopenic Purpura / Immune Thrombocytopenic Purpura (ITP) / Idiopathic Thrombopenic Purpura (ITP) / Immune (Idiopathic) Thrombocytopenic Purpura (ITP) / Immune Thrombocytopenia / ITP / Idiopathic Thrombocytopenic Purpura (ITP) / ITP - Immune Thrombocytopenic Purpura / Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) / Immune Thrombocytopenic Purpura ( ITP ) / Immune Thrombocytopenia (ITP) / Thrombocytopenic Purpura, Immune / Idiopathic Thrombocytopenia Purpura / Immune (Idiopathic) Thrombocytopenic Purpura / Thrombocytopenia (& [auto-immune]) / Immune thrombocytopenia (disorder) / Autoimmune thrombocytopenia / Autoimmune thrombocytopenia (disorder) / Chronic idiopathic thrombocytopenic purpura (disorder) / Immune thrombocytopenic purpura (disorder) / Hemorrhagic (thrombocytopenic) purpura / Werlhof's syndrome / Idiopathic purpura / (Thrombocytopenia: [primary] or [idopathic purpuric] or [idiopathic] or [purpuric]) or (Evan's syndrome) / Thrombocytopenic purpura: [primary] or [idiopathic] / Idiopathic purpura (& thrombocytopenic)

DrugDrug NameDrug Description
DB00993AzathioprineAn immunosuppressant used to prevent renal transplant rejection, treat rheumatoid arthritis, Crohn's disease, and ulcerative colitis.
DB01380Cortisone acetateA steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones.
DB00091CyclosporineA steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis.
DB01234DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
DB00741HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
DB14545Hydrocortisone succinateA corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders.
DB00959MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
DB14644Methylprednisolone hemisuccinateA water soluble corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders.
DB00860PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
DB00635PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
DB00570VinblastineA vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
DB00541VincristineA vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
DrugDrug NameTargetType
DB00993AzathioprineThiopurine S-methyltransferaseenzyme
DB00993AzathioprineXanthine dehydrogenase/oxidaseenzyme
DB00993AzathioprineGlutathione S-transferase A1enzyme
DB00993AzathioprineGlutathione S-transferase A2enzyme
DB00993AzathioprineGlutathione S-transferase Mu 1enzyme
DB00993AzathioprineRas-related C3 botulinum toxin substrate 1target
DB00993AzathioprineCytochrome P450 1A2enzyme
DB00993AzathioprineHypoxanthine-guanine phosphoribosyltransferaseenzyme
DB00993AzathioprineNucleotide triphosphate diphosphatase NUDT15enzyme
DB00993AzathioprineEquilibrative nucleoside transporter 2transporter
DB00993AzathioprineSolute carrier family 28 member 3transporter
DB00993AzathioprineP-glycoprotein 1transporter
DB00993AzathioprineSolute carrier family 43 member 3transporter
DB00993AzathioprineSerum albumincarrier
DB00993AzathioprineInosine-5'-monophosphate dehydrogenase 1enzyme
DB00993AzathioprineInosine-5'-monophosphate dehydrogenase 2enzyme
DB00993AzathioprineGMP synthase [glutamine-hydrolyzing]enzyme
DB00993AzathioprineInosine triphosphate pyrophosphataseenzyme
DB01380Cortisone acetateGlucocorticoid receptortarget
DB01380Cortisone acetateCytochrome P450 3A4enzyme
DB01380Cortisone acetateCytochrome P450 3A5enzyme
DB01380Cortisone acetateAnnexin A1target
DB01380Cortisone acetateCorticosteroid-binding globulincarrier
DB01380Cortisone acetateSerum albumincarrier
DB01380Cortisone acetateSolute carrier organic anion transporter family member 1A2transporter
DB01380Cortisone acetateP-glycoprotein 1transporter
DB01380Cortisone acetateSolute carrier family 22 member 8transporter
DB00091CyclosporineCalcium signal-modulating cyclophilin ligandtarget
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase Atarget
DB00091CyclosporineCalcineurin subunit B type 2target
DB00091CyclosporineCytochrome P450 3A5enzyme
DB00091CyclosporineCytochrome P450 3A4enzyme
DB00091CyclosporineP-glycoprotein 1transporter
DB00091CyclosporineBile salt export pumptransporter
DB00091CyclosporineIleal sodium/bile acid cotransportertransporter
DB00091CyclosporineSodium/bile acid cotransportertransporter
DB00091CyclosporineSolute carrier family 22 member 6transporter
DB00091CyclosporineMultidrug resistance-associated protein 7transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 1transporter
DB00091CyclosporineATP-binding cassette sub-family G member 2transporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1B1transporter
DB00091CyclosporineCytochrome P450 2C19enzyme
DB00091CyclosporineCytochrome P450 2D6enzyme
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
DB00091CyclosporineSolute carrier organic anion transporter family member 1B3transporter
DB01234DexamethasoneGlucocorticoid receptortarget
DB01234DexamethasoneAnnexin A1target
DB01234DexamethasoneNitric oxide synthase, inducibletarget
DB01234DexamethasoneNuclear receptor subfamily 0 group B member 1target
DB01234DexamethasoneCytochrome P450 3A4enzyme
DB01234DexamethasoneCytochrome P450 3A5enzyme
DB01234DexamethasoneCytochrome P450 3A7enzyme
DB01234DexamethasoneBile salt export pumptransporter
DB01234DexamethasoneP-glycoprotein 1transporter
DB01234DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DB01234DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DB01234DexamethasoneATP-binding cassette sub-family G member 2transporter
DB01234DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01234DexamethasoneCytochrome P450 1A1enzyme
DB01234DexamethasoneCytochrome P450 2A6enzyme
DB01234DexamethasoneCytochrome P450 2B6enzyme
DB01234DexamethasoneCytochrome P450 2C19enzyme
DB01234DexamethasoneCytochrome P450 2C8enzyme
DB01234DexamethasoneCytochrome P450 2E1enzyme
DB01234DexamethasoneCytochrome P450 3A43enzyme
DB01234DexamethasoneCytochrome P450 4A11enzyme
DB01234DexamethasoneNuclear receptor subfamily 1 group I member 2target
DB01234DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DB01234DexamethasoneSerum albumincarrier
DB01234DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DB01234DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB01234DexamethasoneSolute carrier family 22 member 8transporter
DB00741HydrocortisoneAnnexin A1target
DB00741HydrocortisoneGlucocorticoid receptortarget
DB00741HydrocortisoneSex hormone-binding globulincarrier
DB00741HydrocortisoneCytochrome P450 3A4enzyme
DB00741HydrocortisoneCytochrome P450 3A5enzyme
DB00741HydrocortisoneCytochrome P450 3A7enzyme
DB00741HydrocortisoneP-glycoprotein 1transporter
DB00741HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
DB00741HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 2C8enzyme
DB00741HydrocortisoneCorticosteroid-binding globulincarrier
DB00741HydrocortisoneSolute carrier family 22 member 8transporter
DB00741Hydrocortisone3-oxo-5-beta-steroid 4-dehydrogenaseenzyme
DB00741Hydrocortisone3-oxo-5-alpha-steroid 4-dehydrogenase 2enzyme
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB00741HydrocortisoneCytochrome P450 2A6enzyme
DB00741HydrocortisoneCytochrome P450 1B1enzyme
DB00741HydrocortisoneCytochrome P450 2B6enzyme
DB00741HydrocortisoneCytochrome P450 2C9enzyme
DB00741HydrocortisoneCytochrome P450 2C19enzyme
DB14545Hydrocortisone succinateCytochrome P450 3A4enzyme
DB14545Hydrocortisone succinateCytochrome P450 2C8enzyme
DB14545Hydrocortisone succinateCytochrome P450 11B1, mitochondrialenzyme
DB14545Hydrocortisone succinateCytochrome P450 11B2, mitochondrialenzyme
DB00959MethylprednisoloneGlucocorticoid receptortarget
DB00959MethylprednisoloneCytochrome P450 3A4enzyme
DB00959MethylprednisoloneP-glycoprotein 1transporter
DB00959MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
DB00959MethylprednisoloneCytochrome P450 2A6enzyme
DB00959MethylprednisoloneCytochrome P450 1B1enzyme
DB00959MethylprednisoloneCytochrome P450 2B6enzyme
DB00959MethylprednisoloneCytochrome P450 2C8enzyme
DB00959MethylprednisoloneCytochrome P450 2C9enzyme
DB00959MethylprednisoloneCytochrome P450 2C19enzyme
DB00959MethylprednisoloneAnnexin A1target
DB00959Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
DB00959Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
DB00959MethylprednisoloneSerum albumincarrier
DB14644Methylprednisolone hemisuccinateCytochrome P450 3A4enzyme
DB14644Methylprednisolone hemisuccinateCytochrome P450 3A5enzyme
DB00860PrednisoloneCorticosteroid-binding globulincarrier
DB00860PrednisoloneCytochrome P450 3A4enzyme
DB00860PrednisoloneGlucocorticoid receptortarget
DB00860PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
DB00860PrednisoloneP-glycoprotein 1transporter
DB00860PrednisoloneSerum albumincarrier
DB00635PrednisoneGlucocorticoid receptortarget
DB00635PrednisoneCytochrome P450 3A4enzyme
DB00635PrednisoneP-glycoprotein 1transporter
DB00635PrednisoneSolute carrier organic anion transporter family member 1A2transporter
DB00635PrednisoneCytochrome P450 2C19enzyme
DB00635PrednisoneSerum albumincarrier
DB00635PrednisoneCytochrome P450 3A5enzyme
DB00635PrednisoneCorticosteroid-binding globulincarrier
DB00635PrednisoneCytochrome P450 3A Subfamilyenzyme
DB00635PrednisoneCytochrome P450 2A6enzyme
DB00635PrednisoneCytochrome P450 1B1enzyme
DB00635PrednisoneCytochrome P450 2B6enzyme
DB00635PrednisoneCytochrome P450 2C8enzyme
DB00635PrednisoneCytochrome P450 2C9enzyme
DB00635PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB00570VinblastineTubulin beta chaintarget
DB00570VinblastineTranscription factor AP-1target
DB00570VinblastineCytochrome P450 3A4enzyme
DB00570VinblastineP-glycoprotein 1transporter
DB00570VinblastineMultidrug resistance-associated protein 1transporter
DB00570VinblastineCanalicular multispecific organic anion transporter 1transporter
DB00570VinblastineMultidrug resistance-associated protein 6transporter
DB00570VinblastineBile salt export pumptransporter
DB00570VinblastineTubulin alpha-1A chaintarget
DB00570VinblastineTubulin delta chaintarget
DB00570VinblastineTubulin epsilon chaintarget
DB00570VinblastineTubulin gamma-1 chaintarget
DB00570VinblastineCytochrome P450 2D6enzyme
DB00570VinblastineSolute carrier organic anion transporter family member 1B1transporter
DB00541VincristineTubulin beta chaintarget
DB00541VincristineCytochrome P450 3A4enzyme
DB00541VincristineCytochrome P450 3A5enzyme
DB00541VincristineCytochrome P450 3A7enzyme
DB00541VincristineP-glycoprotein 1transporter
DB00541VincristineCanalicular multispecific organic anion transporter 2transporter
DB00541VincristineSolute carrier family 22 member 3transporter
DB00541VincristineMultidrug resistance-associated protein 1transporter
DB00541VincristineMultidrug resistance-associated protein 7transporter
DB00541VincristineCanalicular multispecific organic anion transporter 1transporter
DB00541VincristineBile salt export pumptransporter
DB00541VincristineATP-binding cassette sub-family G member 2transporter
DB00541VincristineTubulin alpha-4A chaintarget
DB00541VincristineRalA-binding protein 1transporter
DB00541VincristineSolute carrier organic anion transporter family member 1B1transporter
DB00541VincristineSolute carrier organic anion transporter family member 1B3transporter
DrugDrug NamePhaseStatusCount
DB00316Acetaminophen1Not Yet Recruiting1
DB11995Avatrombopag1Completed4
DB15301Bevifimod1Terminated1
DB00091Cyclosporine1Completed2
DB01075Diphenhydramine1Not Yet Recruiting1
DB06210Eltrombopag1Completed2
DB06210Eltrombopag1Recruiting1
DB15397GMA-1611Terminated1
DB16364Recombinant Human Thrombopoietin1Recruiting1
DB00073Rituximab1Recruiting1
DB09536Titanium dioxide1Completed1
DB00661Verapamil1Completed1
DB09321Zinc oxide1Completed1
DB06151Acetylcysteine1 / 2Not Yet Recruiting1
DB01076Atorvastatin1 / 2Not Yet Recruiting1
DB15301Bevifimod1 / 2Terminated2
DB01406Danazol1 / 2Not Yet Recruiting1
DB00028Human immunoglobulin G1 / 2Terminated1
DB00073Rituximab1 / 2Completed1
DB05332Romiplostim1 / 2Completed2
DB00877Sirolimus1 / 2Completed1
DB05656Veltuzumab1 / 2Terminated1
DB06151Acetylcysteine2Recruiting1
DB11995Avatrombopag2Completed2
DB00188Bortezomib2Unknown Status1
DB01406Danazol2Not Yet Recruiting1
DB01406Danazol2Recruiting1
DB09331Daratumumab2Recruiting1
DB01262Decitabine2Completed1
DB01234Dexamethasone2Completed3
DB01234Dexamethasone2Recruiting6
DB01234Dexamethasone2Unknown Status2
DB01234Dexamethasone2Withdrawn1
DB06210Eltrombopag2Active Not Recruiting1
DB06210Eltrombopag2Completed4
DB06210Eltrombopag2Recruiting2
DB06210Eltrombopag2Suspended1
DB06210Eltrombopag2Unknown Status1
DB12010Fostamatinib2Completed1
DB00028Human immunoglobulin G2Completed2
DB09570Ixazomib2Withdrawn1
DB16070KZR-6162Withdrawn1
DB13125Lusutrombopag2Terminated2
DB00959Methylprednisolone2Unknown Status1
DB16272Orelabrutinib2Not Yet Recruiting1
DB16364Recombinant Human Thrombopoietin2Recruiting1
DB00073Rituximab2Active Not Recruiting1
DB00073Rituximab2Completed4
DB00073Rituximab2Recruiting1
DB00073Rituximab2Unknown Status2
DB00073Rituximab2Withdrawn1
DB05332Romiplostim2Completed4
DB05332Romiplostim2Not Yet Recruiting1
DB05332Romiplostim2Recruiting1
DB05332Romiplostim2Unknown Status1
DB05209Rozrolimupab2Completed1
DB00864Tacrolimus2Recruiting1
DB00871Terbutaline2Recruiting1
DB01041Thalidomide2Withdrawn1
DB00755Tretinoin2Active Not Recruiting1
DB00755Tretinoin2Not Yet Recruiting1
DB00755Tretinoin2Recruiting1
DB00087Alemtuzumab2 / 3Completed1
DB01076Atorvastatin2 / 3Not Yet Recruiting1
DB12330Blisibimod2 / 3Withdrawn1
DB00531Cyclophosphamide2 / 3Completed1
DB01234Dexamethasone2 / 3Completed1
DB01234Dexamethasone2 / 3Not Yet Recruiting1
DB01234Dexamethasone2 / 3Unknown Status1
DB00635Prednisone2 / 3Completed2
DB00073Rituximab2 / 3Completed2
DB05332Romiplostim2 / 3Completed1
DB00541Vincristine2 / 3Completed1
DB11995Avatrombopag3Completed1
DB11995Avatrombopag3Recruiting1
DB11995Avatrombopag3Terminated1
DB00188Bortezomib3Not Yet Recruiting1
DB00091Cyclosporine3Unknown Status1
DB00091Cyclosporine3Withdrawn1
DB01262Decitabine3Not Yet Recruiting1
DB01234Dexamethasone3Completed6
DB01234Dexamethasone3Not Yet Recruiting2
DB01234Dexamethasone3Recruiting1
DB01234Dexamethasone3Terminated1
DB01234Dexamethasone3Withdrawn3
DB06210Eltrombopag3Completed5
DB06210Eltrombopag3Recruiting1
DB06210Eltrombopag3Terminated1
DB06210Eltrombopag3Unknown Status1
DB12010Fostamatinib3Completed3
DB16184Hetrombopag3Not Yet Recruiting1
DB00028Human immunoglobulin G3Completed7
DB00028Human immunoglobulin G3Not Yet Recruiting1
DB00028Human immunoglobulin G3Unknown Status1
DB00741Hydrocortisone3Not Yet Recruiting1
DB00959Methylprednisolone3Completed1
DB00688Mycophenolate mofetil3Active Not Recruiting1
DB00688Mycophenolate mofetil3Withdrawn1
DB00198Oseltamivir3Recruiting1
DB00860Prednisolone3Active Not Recruiting1
DB00860Prednisolone3Completed1
DB00635Prednisone3Completed1
DB00635Prednisone3Terminated1
DB16364Recombinant Human Thrombopoietin3Completed5
DB16364Recombinant Human Thrombopoietin3Not Yet Recruiting1
DB16364Recombinant Human Thrombopoietin3Unknown Status2
DB16364Recombinant Human Thrombopoietin3Withdrawn2
DB00073Rituximab3Completed5
DB00073Rituximab3Not Yet Recruiting1
DB00073Rituximab3Recruiting1
DB00073Rituximab3Withdrawn3
DB05332Romiplostim3Completed9
DB00755Tretinoin3Withdrawn1
DB01060Amoxicillin4Recruiting1
DB11995Avatrombopag4Recruiting2
DB00993Azathioprine4Completed1
DB00136Calcitriol4Not Yet Recruiting1
DB01211Clarithromycin4Recruiting1
DB01234Dexamethasone4Completed2
DB01234Dexamethasone4Not Yet Recruiting1
DB01234Dexamethasone4Recruiting1
DB01234Dexamethasone4Withdrawn1
DB06210Eltrombopag4Completed1
DB06210Eltrombopag4Not Yet Recruiting1
DB06210Eltrombopag4Recruiting1
DB00028Human immunoglobulin G4Completed1
DB01611Hydroxychloroquine4Completed1
DB00825Levomenthol4Withdrawn1
DB00635Prednisone4Completed1
DB00073Rituximab4Completed1
DB00073Rituximab4Recruiting1
DB05332Romiplostim4Completed2
DB00541Vincristine4Completed1
DB11995AvatrombopagNot AvailableNot Yet Recruiting1
DB00993AzathioprineNot AvailableRecruiting1
DB08879BelimumabNot AvailableCompleted1
DB00091CyclosporineNot AvailableNot Yet Recruiting1
DB01234DexamethasoneNot AvailableNot Yet Recruiting2
DB06210EltrombopagNot AvailableCompleted2
DB06210EltrombopagNot AvailableRecruiting2
DB06210EltrombopagNot AvailableTerminated1
DB12010FostamatinibNot AvailableNo Longer Available1
DB12010FostamatinibNot AvailableRecruiting1
DB01033MercaptopurineNot AvailableCompleted1
DB00688Mycophenolate mofetilNot AvailableCompleted1
DB00688Mycophenolate mofetilNot AvailableRecruiting1
DB00073RituximabNot AvailableCompleted3
DB00073RituximabNot AvailableNot Yet Recruiting1
DB00073RituximabNot AvailableRecruiting1
DB00073RituximabNot AvailableWithdrawn1
DB05332RomiplostimNot AvailableCompleted2
DB00877SirolimusNot AvailableCompleted2
DB06534ThrombopoietinNot AvailableRecruiting1
DB00755TretinoinNot AvailableCompleted1