Rejection, Transplant

Also known as: Transplant rejections / Graft Rejection / Transplant Rejection / Transplanted Organ Rejection / Organ Transplant Rejection / Transplanted organ rejection (disorder) / Graft rejection (finding) / Complication of transplanted organ (disorder)

DrugDrug NameDrug Description
DB00091CyclosporineA steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis.
DB00860PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
DB15566Prednisolone acetateA glucocorticoid used to treat a wide variety of endocrine, inflammatory, and immune conditions as well as for palliation of neoplastic conditions.
DB00877SirolimusAn mTOR inhibitor immunosuppressant used to prevent organ transplant rejections, treat lymphangioleiomyomatosis, and treat adults with perivascular epithelioid cell tumors.
DrugDrug NameTargetType
DB00091CyclosporineCalcium signal-modulating cyclophilin ligandtarget
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase Atarget
DB00091CyclosporineCalcineurin subunit B type 2target
DB00091CyclosporineCytochrome P450 3A5enzyme
DB00091CyclosporineCytochrome P450 3A4enzyme
DB00091CyclosporineP-glycoprotein 1transporter
DB00091CyclosporineBile salt export pumptransporter
DB00091CyclosporineIleal sodium/bile acid cotransportertransporter
DB00091CyclosporineSodium/bile acid cotransportertransporter
DB00091CyclosporineSolute carrier family 22 member 6transporter
DB00091CyclosporineMultidrug resistance-associated protein 7transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 1transporter
DB00091CyclosporineATP-binding cassette sub-family G member 2transporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1B1transporter
DB00091CyclosporineCytochrome P450 2C19enzyme
DB00091CyclosporineCytochrome P450 2D6enzyme
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
DB00091CyclosporineSolute carrier organic anion transporter family member 1B3transporter
DB00860PrednisoloneCorticosteroid-binding globulincarrier
DB00860PrednisoloneCytochrome P450 3A4enzyme
DB00860PrednisoloneGlucocorticoid receptortarget
DB00860PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
DB00860PrednisoloneP-glycoprotein 1transporter
DB00860PrednisoloneSerum albumincarrier
DB15566Prednisolone acetateCorticosteroid-binding globulincarrier
DB15566Prednisolone acetateCytochrome P450 3A4enzyme
DB15566Prednisolone acetateGlucocorticoid receptortarget
DB15566Prednisolone acetateSolute carrier organic anion transporter family member 1A2transporter
DB15566Prednisolone acetateP-glycoprotein 1transporter
DB15566Prednisolone acetateSerum albumincarrier
DB00877SirolimusCytochrome P450 3A4enzyme
DB00877SirolimusSerine/threonine-protein kinase mTORtarget
DB00877SirolimusCytochrome P450 3A5enzyme
DB00877SirolimusCytochrome P450 3A7enzyme
DB00877SirolimusP-glycoprotein 1transporter
DB00877SirolimusSolute carrier organic anion transporter family member 1B1transporter
DB00877SirolimusMultidrug and toxin extrusion protein 1transporter
DB00877SirolimusSerum albumincarrier
DB00877SirolimusAlpha-1-acid glycoprotein 1carrier
DB00877SirolimusApolipoproteinscarrier
DrugDrug NamePhaseStatusCount
DB00864Tacrolimus0Completed1
DB00877Sirolimus1Completed1
DB00316Acetaminophen2Completed1
DB00087Alemtuzumab2Completed1
DB00098Antithymocyte immunoglobulin (rabbit)2Completed3
DB06681Belatacept2Active Not Recruiting1
DB06681Belatacept2Completed1
DB00188Bortezomib2Completed1
DB16741Bortezomib D-mannitol2Completed1
DB00091Cyclosporine2Completed1
DB01075Diphenhydramine2Completed1
DB08868Fingolimod2Not Yet Recruiting1
DB06404Human C1-esterase inhibitor2Completed1
DB06404Human C1-esterase inhibitor2Withdrawn1
DB00028Human immunoglobulin G2Recruiting1
DB11228Methylcellulose2Not Yet Recruiting1
DB00959Methylprednisolone2Completed1
DB00688Mycophenolate mofetil2Completed2
DB01024Mycophenolic acid2Recruiting1
DB00073Rituximab2Completed1
DB00073Rituximab2Recruiting1
DB00864Tacrolimus2Completed1
DB00864Tacrolimus2Recruiting1
DB00074Basiliximab3Completed1
DB00091Cyclosporine3Completed3
DB01590Everolimus3Completed3
DB00688Mycophenolate mofetil3Completed1
DB01024Mycophenolic acid3Completed1
DB00073Rituximab3Unknown Status1
DB09153Sodium chloride3Unknown Status1
DB09154Sodium citrate3Unknown Status1
DB00864Tacrolimus3Completed1
DB00087Alemtuzumab4Completed1
DB00098Antithymocyte immunoglobulin (rabbit)4Unknown Status1
DB00207Azithromycin4Completed1
DB06681Belatacept4Completed1
DB00201Caffeine4Completed1
DB00091Cyclosporine4Completed1
DB00091Cyclosporine4Unknown Status1
DB00514Dextromethorphan4Completed1
DB04465Lactose4Completed1
DB00678Losartan4Completed1
DB00959Methylprednisolone4Completed1
DB00683Midazolam4Completed1
DB00471Montelukast4Completed1
DB00688Mycophenolate mofetil4Completed1
DB00688Mycophenolate mofetil4Unknown Status1
DB01024Mycophenolic acid4Unknown Status1
DB00338Omeprazole4Completed1
DB00860Prednisolone4Completed1
DB00635Prednisone4Unknown Status1
DB00073Rituximab4Completed1
DB00877Sirolimus4Completed5
DB00877Sirolimus4Unknown Status1
DB00864Tacrolimus4Completed5
DB00864Tacrolimus4Unknown Status1
DB00087AlemtuzumabNot AvailableActive Not Recruiting1