Advanced Breast Cancer

Also known as: Malignant neoplasm of breast / Malignant breast neoplasm / Breast cancer / Breast tumor malignant / Breast tumour malignant / Breast cancer NOS / Breast cancer stage unspecified / Ca breast

DrugDrug NameDrug Description
DB01217AnastrozoleA competitive, selective, non-steroidal aromatase inhibitor used as adjuvant therapy for the treatment of hormone receptor-positive breast cancer in postmenopausal women.
DB06374ElacestrantAn estrogen receptor antagonist used to treat ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy.
DB00947FulvestrantAn estrogen receptor antagonist used to treat HR+ breast cancer that may also be HER2-.
DB00014GoserelinA synthetic analog of luteinizing hormone-releasing hormone used to treat breast cancer and prostate cancer by reducing secretion of gonadotropins from the pituitary.
DB01006LetrozoleAn aromatase inhibitor used to treat breast cancer in postmenopausal women.
DB09073PalbociclibAn endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer.
DB11730RibociclibA kinase inhibitor used to treat HR+, HER2- advanced or metastatic breast cancer.
DrugDrug NameTargetType
DB01217AnastrozoleAromatasetarget
DB01217AnastrozoleATP-dependent translocase ABCB1transporter
DB01217AnastrozoleCytochrome P450 3A4enzyme
DB01217AnastrozoleCytochrome P450 3A5enzyme
DB01217AnastrozoleCytochrome P450 2C8enzyme
DB01217AnastrozoleUDP-glucuronosyltransferase 1A4enzyme
DB01217AnastrozoleUDP-glucuronosyltransferase 1A3enzyme
DB01217AnastrozoleUDP-glucuronosyltransferase 2B7enzyme
DB01217AnastrozoleCytochrome P450 1A2enzyme
DB01217AnastrozoleCytochrome P450 2C9enzyme
DB06374ElacestrantEstrogen receptortarget
DB06374ElacestrantCytochrome P450 3A4enzyme
DB06374ElacestrantCytochrome P450 2A6enzyme
DB06374ElacestrantCytochrome P450 2C9enzyme
DB06374ElacestrantSolute carrier organic anion transporter family member 2B1transporter
DB06374ElacestrantATP-dependent translocase ABCB1transporter
DB06374ElacestrantBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
DB00947FulvestrantEstrogen receptortarget
DB00947FulvestrantCytochrome P450 3A4enzyme
DB00947FulvestrantUDP-glucuronosyltransferase 1A1enzyme
DB00014GoserelinLutropin-choriogonadotropic hormone receptortarget
DB00014GoserelinGonadotropin-releasing hormone receptortarget
DB00014GoserelinProgonadoliberin-1target
DB01006LetrozoleAromatasetarget
DB01006LetrozoleCytochrome P450 3A4enzyme
DB01006LetrozoleCytochrome P450 2A6enzyme
DB01006LetrozoleAromataseenzyme
DB01006LetrozoleCytochrome P450 2C19enzyme
DB01006LetrozoleUDP-glucuronosyltransferase 2B7enzyme
DB01006LetrozoleAlbumincarrier
DB01006LetrozoleATP-dependent translocase ABCB1transporter
DB09073PalbociclibCyclin-dependent kinase 4target
DB09073PalbociclibCyclin-dependent kinase 6target
DB09073PalbociclibCytochrome P450 3A4enzyme
DB09073PalbociclibSulfotransferase 2A1enzyme
DB09073PalbociclibATP-dependent translocase ABCB1transporter
DB09073PalbociclibBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
DB09073PalbociclibAlbumincarrier
DB09073PalbociclibSolute carrier family 22 member 1transporter
DB11730RibociclibCyclin-dependent kinase 4target
DB11730RibociclibCyclin-dependent kinase 6target
DB11730RibociclibCytochrome P450 3A4enzyme
DrugDrug NamePhaseStatusCount
DB01217AnastrozoleNot AvailableCompleted1
DB17456DalpiciclibNot AvailableNot Yet Recruiting1
DB17208Disitamab vedotinNot AvailableRecruiting1
DB06374ElacestrantNot AvailableRecruiting1
DB08871EribulinNot AvailableUnknown Status1
DB00947FulvestrantNot AvailableActive Not Recruiting1
DB00947FulvestrantNot AvailableUnknown Status1
DB01006LetrozoleNot AvailableActive Not Recruiting1
DB09073PalbociclibNot AvailableActive Not Recruiting1
DB09073PalbociclibNot AvailableCompleted1
DB00635PrednisoneNot AvailableRecruiting1
DB01268SunitinibNot AvailableCompleted1
DB06334TucidinostatNot AvailableUnknown Status1
DB00361VinorelbineNot AvailableNot Yet Recruiting1
DB12001Abemaciclib1Active Not Recruiting2
DB12001Abemaciclib1Withdrawn1
DB00041Aldesleukin1Not Yet Recruiting1
DB12015Alpelisib1Active Not Recruiting1
DB12015Alpelisib1Recruiting1
DB01217Anastrozole1Withdrawn1
DB01101Capecitabine1Completed1
DB01254Dasatinib1Completed1
DB01262Decitabine1Unknown Status1
DB01248Docetaxel1Completed1
DB00997Doxorubicin1Completed1
DB01590Everolimus1Active Not Recruiting1
DB00990Exemestane1Unknown Status1
DB00947Fulvestrant1Active Not Recruiting3
DB00947Fulvestrant1Completed1
DB00947Fulvestrant1Recruiting2
DB00947Fulvestrant1Unknown Status1
DB00947Fulvestrant1Withdrawn1
DB01611Hydroxychloroquine1Withdrawn1
DB19043Imlunestrant1Active Not Recruiting1
DB00762Irinotecan1Completed1
DB01006Letrozole1Active Not Recruiting1
DB01006Letrozole1Recruiting1
DB01006Letrozole1Unknown Status3
DB01006Letrozole1Withdrawn1
DB12852MK-07521Completed1
DB09074Olaparib1Active Not Recruiting1
DB01229Paclitaxel1Completed1
DB01229Paclitaxel1Unknown Status3
DB18971Palazestrant1Recruiting1
DB09073Palbociclib1Active Not Recruiting2
DB09073Palbociclib1Completed2
DB09073Palbociclib1Recruiting2
DB09073Palbociclib1Unknown Status2
DB06366Pertuzumab1Active Not Recruiting1
DB16751RLY-26081Recruiting1
DB11730Ribociclib1Active Not Recruiting1
DB11730Ribociclib1Completed1
DB11730Ribociclib1Recruiting2
DB09143Sonidegib1Completed1
DB14876TAS-1161Recruiting1
DB00072Trastuzumab1Active Not Recruiting1
DB05773Trastuzumab emtansine1Completed1
DB02546Vorinostat1Completed1
DB08916Afatinib1 / 2Terminated1
DB01217Anastrozole1 / 2Completed1
DB15370Balixafortide1 / 2Withdrawn1
DB17456Dalpiciclib1 / 2Completed1
DB17208Disitamab vedotin1 / 2Recruiting1
DB08871Eribulin1 / 2Withdrawn1
DB00947Fulvestrant1 / 2Completed1
DB00947Fulvestrant1 / 2Withdrawn1
DB01611Hydroxychloroquine1 / 2Recruiting1
DB01006Letrozole1 / 2Completed1
DB11828Neratinib1 / 2Completed2
DB11793Niraparib1 / 2Completed1
DB09074Olaparib1 / 2Recruiting1
DB01229Paclitaxel1 / 2Completed1
DB01229Paclitaxel1 / 2Withdrawn1
DB09037Pembrolizumab1 / 2Active Not Recruiting1
DB09037Pembrolizumab1 / 2Completed1
DB12893Sacituzumab govitecan1 / 2Recruiting1
DB12275Seviteronel1 / 2Completed1
DB11760Talazoparib1 / 2Completed1
DB00072Trastuzumab1 / 2Completed1
DB14962Trastuzumab deruxtecan1 / 2Recruiting1
DB11652Tucatinib1 / 2Recruiting1
DB12001Abemaciclib2Active Not Recruiting1
DB12001Abemaciclib2Recruiting2
DB16412Adebrelimab2Not Yet Recruiting2
DB12015Alpelisib2Active Not Recruiting1
DB12015Alpelisib2Recruiting1
DB12015Alpelisib2Terminated1
DB01217Anastrozole2Terminated1
DB11595Atezolizumab2Completed1
DB00112Bevacizumab2Completed1
DB06616Bosutinib2Terminated1
DB15279CB-1032Terminated1
DB13051CH-51327992Recruiting1
DB14776Camrelizumab2Recruiting1
DB09061Cannabidiol2Active Not Recruiting1
DB01101Capecitabine2Completed1
DB01101Capecitabine2Not Yet Recruiting2
DB01101Capecitabine2Recruiting3
DB01101Capecitabine2Terminated1
DB01101Capecitabine2Unknown Status2
DB01101Capecitabine2Withdrawn1
DB12218Capivasertib2Unknown Status1
DB00958Carboplatin2Recruiting1
DB04849Cediranib2Completed1
DB14917Ceralasertib2Unknown Status1
DB00515Cisplatin2Unknown Status1
DB11672Curcumin2Completed1
DB00531Cyclophosphamide2Recruiting1
DB17456Dalpiciclib2Not Yet Recruiting1
DB17456Dalpiciclib2Recruiting2
DB17456Dalpiciclib2Unknown Status2
DB01254Dasatinib2Completed2
DB01234Dexamethasone2Completed1
DB01248Docetaxel2Completed1
DB01248Docetaxel2Unknown Status1
DB00997Doxorubicin2Recruiting1
DB00997Doxorubicin2Unknown Status1
DB08899Enzalutamide2Completed1
DB08871Eribulin2Recruiting3
DB18923Ertumaxomab2Terminated2
DB01590Everolimus2Completed2
DB01590Everolimus2Recruiting3
DB00990Exemestane2Completed2
DB00990Exemestane2Terminated1
DB11741Famitinib2Recruiting1
DB11741Famitinib2Unknown Status1
DB15637Fluzoparib2Recruiting1
DB00947Fulvestrant2Active Not Recruiting1
DB00947Fulvestrant2Completed5
DB00947Fulvestrant2Not Yet Recruiting2
DB00947Fulvestrant2Recruiting4
DB00947Fulvestrant2Terminated2
DB00947Fulvestrant2Unknown Status1
DB00441Gemcitabine2Completed1
DB00441Gemcitabine2Recruiting1
DB00014Goserelin2Completed1
DB00014Goserelin2Recruiting1
DB00014Goserelin2Terminated1
DB11743Ipatasertib2Recruiting1
DB01259Lapatinib2Completed1
DB01259Lapatinib2Terminated1
DB12984Larotaxel2Completed1
DB16218Lerociclib2Terminated1
DB01006Letrozole2Completed1
DB01006Letrozole2Terminated2
DB01006Letrozole2Unknown Status1
DB14967Margetuximab2Withdrawn1
DB00218Moxifloxacin2Completed1
DB11828Neratinib2Completed1
DB11828Neratinib2Recruiting1
DB11828Neratinib2Unknown Status1
DB09074Olaparib2Completed1
DB09074Olaparib2Not Yet Recruiting1
DB09074Olaparib2Terminated1
DB09074Olaparib2Unknown Status1
DB14954PIK3CA2Recruiting1
DB01229Paclitaxel2Completed2
DB01229Paclitaxel2Recruiting1
DB09073Palbociclib2Completed1
DB09073Palbociclib2Recruiting1
DB09037Pembrolizumab2Completed1
DB06366Pertuzumab2Recruiting1
DB14993Pyrotinib2Not Yet Recruiting1
DB14993Pyrotinib2Unknown Status1
DB11730Ribociclib2Recruiting2
DB14765Rivoceranib2Not Yet Recruiting1
DB12893Sacituzumab govitecan2Recruiting2
DB11760Talazoparib2Completed1
DB11760Talazoparib2Recruiting3
DB00072Trastuzumab2Completed2
DB00072Trastuzumab2Recruiting1
DB00072Trastuzumab2Terminated1
DB00072Trastuzumab2Unknown Status1
DB14962Trastuzumab deruxtecan2Completed1
DB14962Trastuzumab deruxtecan2Not Yet Recruiting1
DB14962Trastuzumab deruxtecan2Recruiting1
DB05773Trastuzumab emtansine2Recruiting2
DB11652Tucatinib2Recruiting1
DB11652Tucatinib2Withdrawn1
DB17575Utidelone2Recruiting1
DB05294Vandetanib2Completed1
DB00361Vinorelbine2Recruiting3
DB05773Trastuzumab emtansine2 / 3Recruiting1
DB17391Trastuzumab vedotin2 / 3Recruiting1
DB12001Abemaciclib3Recruiting1
DB00062Albumin human3Not Yet Recruiting1
DB12015Alpelisib3Active Not Recruiting1
DB01217Anastrozole3Completed2
DB01217Anastrozole3Not Yet Recruiting1
DB01217Anastrozole3Recruiting3
DB01217Anastrozole3Unknown Status1
DB19218Camizestrant3Recruiting1
DB01101Capecitabine3Active Not Recruiting1
DB17456Dalpiciclib3Recruiting1
DB17456Dalpiciclib3Unknown Status2
DB01234Dexamethasone3Not Yet Recruiting1
DB01248Docetaxel3Withdrawn1
DB06374Elacestrant3Not Yet Recruiting1
DB11841Entinostat3Unknown Status1
DB08871Eribulin3Active Not Recruiting1
DB01175Escitalopram3Not Yet Recruiting1
DB00783Estradiol3Not Yet Recruiting1
DB01590Everolimus3Not Yet Recruiting1
DB00990Exemestane3Recruiting2
DB00990Exemestane3Unknown Status1
DB00947Fulvestrant3Active Not Recruiting2
DB00947Fulvestrant3Completed3
DB00947Fulvestrant3Recruiting4
DB00947Fulvestrant3Unknown Status2
DB00441Gemcitabine3Completed1
DB00441Gemcitabine3Terminated1
DB00014Goserelin3Recruiting1
DB00014Goserelin3Unknown Status1
DB01006Letrozole3Not Yet Recruiting1
DB01006Letrozole3Recruiting3
DB01006Letrozole3Unknown Status1
DB14741Luteinizing hormone3Not Yet Recruiting1
DB01229Paclitaxel3Completed1
DB01229Paclitaxel3Not Yet Recruiting1
DB01229Paclitaxel3Terminated1
DB18971Palazestrant3Recruiting1
DB09073Palbociclib3Recruiting1
DB06366Pertuzumab3Withdrawn1
DB11730Ribociclib3Completed1
DB11730Ribociclib3Recruiting1
DB14765Rivoceranib3Recruiting1
DB18982Saruparib3Recruiting1
DB00072Trastuzumab3Active Not Recruiting1
DB00072Trastuzumab3Withdrawn1
DB19006Vepdegestrant3Recruiting1
DB11641Vinflunine3Terminated1
DB00361Vinorelbine3Active Not Recruiting1
DB00361Vinorelbine3Withdrawn1
DB12015Alpelisib4Recruiting1
DB01101Capecitabine4Recruiting1
DB00947Fulvestrant4Recruiting1
DB14993Pyrotinib4Recruiting1
DB11730Ribociclib4Recruiting1
DB00072Trastuzumab4Recruiting1