Advanced Breast Cancer

Also known as: Malignant neoplasm of breast / Malignant breast neoplasm / Breast cancer / Breast tumor malignant / Breast tumour malignant / Breast cancer NOS / Breast cancer stage unspecified / Ca breast

DrugDrug NameDrug Description
DB01217AnastrozoleA competitive, selective, non-steroidal aromatase inhibitor used as adjuvant therapy for the treatment of hormone receptor-positive breast cancer in postmenopausal women.
DB00947FulvestrantAn estrogen receptor antagonist used to treat HR+ breast cancer that may also be HER2-.
DB00014GoserelinA synthetic analog of luteinizing hormone-releasing hormone used to treat breast cancer and prostate cancer by reducing secretion of gonadotropins from the pituitary.
DB01006LetrozoleAn aromatase inhibitor used to treat breast cancer in postmenopausal women.
DB09073PalbociclibAn endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer.
DB11730RibociclibA kinase inhibitor used to treat HR+, HER2- advanced or metastatic breast cancer.
DrugDrug NameTargetType
DB01217AnastrozoleCytochrome P450 19A1target
DB01217AnastrozoleP-glycoprotein 1transporter
DB01217AnastrozoleCytochrome P450 3A4enzyme
DB01217AnastrozoleCytochrome P450 3A5enzyme
DB01217AnastrozoleCytochrome P450 2C8enzyme
DB01217AnastrozoleUDP-glucuronosyltransferase 1-4enzyme
DB01217AnastrozoleUDP-glucuronosyltransferase 1-3enzyme
DB01217AnastrozoleUDP-glucuronosyltransferase 2B7enzyme
DB01217AnastrozoleCytochrome P450 1A2enzyme
DB01217AnastrozoleCytochrome P450 2C9enzyme
DB00947FulvestrantEstrogen receptor alphatarget
DB00947FulvestrantCytochrome P450 3A4enzyme
DB00947FulvestrantUDP-glucuronosyltransferase 1-1enzyme
DB00014GoserelinLutropin-choriogonadotropic hormone receptortarget
DB00014GoserelinGonadotropin-releasing hormone receptortarget
DB01006LetrozoleCytochrome P450 19A1target
DB01006LetrozoleCytochrome P450 3A4enzyme
DB01006LetrozoleCytochrome P450 2A6enzyme
DB01006LetrozoleCytochrome P450 19A1enzyme
DB01006LetrozoleCytochrome P450 2C19enzyme
DB01006LetrozoleUDP-glucuronosyltransferase 2B7enzyme
DB01006LetrozoleSerum albumincarrier
DB01006LetrozoleP-glycoprotein 1transporter
DB09073PalbociclibCyclin-dependent kinase 4target
DB09073PalbociclibCyclin-dependent kinase 6target
DB09073PalbociclibCytochrome P450 3A4enzyme
DB09073PalbociclibBile salt sulfotransferaseenzyme
DB09073PalbociclibP-glycoprotein 1transporter
DB09073PalbociclibATP-binding cassette sub-family G member 2transporter
DB09073PalbociclibSerum albumincarrier
DB09073PalbociclibSolute carrier family 22 member 1transporter
DB11730RibociclibCyclin-dependent kinase 4target
DB11730RibociclibCyclin-dependent kinase 6target
DB11730RibociclibCytochrome P450 3A4enzyme
DrugDrug NamePhaseStatusCount
DB12001Abemaciclib1Recruiting2
DB12015Alpelisib1Recruiting2
DB01217Anastrozole1Recruiting1
DB01101Capecitabine1Completed1
DB01254Dasatinib1Completed1
DB01262Decitabine1Unknown Status1
DB01248Docetaxel1Completed1
DB01590Everolimus1Recruiting1
DB00990Exemestane1Recruiting1
DB00947Fulvestrant1Completed1
DB00947Fulvestrant1Not Yet Recruiting1
DB00947Fulvestrant1Recruiting3
DB01611Hydroxychloroquine1Recruiting1
DB00762Irinotecan1Not Yet Recruiting1
DB01006Letrozole1Active Not Recruiting1
DB01006Letrozole1Not Yet Recruiting1
DB01006Letrozole1Recruiting2
DB12852MK-07521Completed1
DB09074Olaparib1Recruiting1
DB01229Paclitaxel1Active Not Recruiting1
DB01229Paclitaxel1Not Yet Recruiting1
DB01229Paclitaxel1Unknown Status2
DB09073Palbociclib1Active Not Recruiting2
DB09073Palbociclib1Completed1
DB09073Palbociclib1Not Yet Recruiting1
DB09073Palbociclib1Recruiting1
DB06366Pertuzumab1Recruiting1
DB16751RLY-26081Recruiting1
DB11730Ribociclib1Active Not Recruiting1
DB09143Sonidegib1Completed1
DB00072Trastuzumab1Recruiting1
DB05773Trastuzumab emtansine1Completed1
DB02546Vorinostat1Completed1
DB08916Afatinib1 / 2Recruiting1
DB01217Anastrozole1 / 2Active Not Recruiting1
DB15370Balixafortide1 / 2Not Yet Recruiting1
DB08871Eribulin1 / 2Not Yet Recruiting1
DB00947Fulvestrant1 / 2Active Not Recruiting1
DB00947Fulvestrant1 / 2Recruiting1
DB01006Letrozole1 / 2Active Not Recruiting1
DB11828Neratinib1 / 2Completed2
DB11793Niraparib1 / 2Completed1
DB01229Paclitaxel1 / 2Completed1
DB01229Paclitaxel1 / 2Not Yet Recruiting1
DB09037Pembrolizumab1 / 2Completed1
DB09037Pembrolizumab1 / 2Not Yet Recruiting1
DB12275Seviteronel1 / 2Completed1
DB11760Talazoparib1 / 2Completed1
DB00072Trastuzumab1 / 2Completed1
DB12001Abemaciclib2Not Yet Recruiting1
DB12001Abemaciclib2Recruiting1
DB12015Alpelisib2Recruiting2
DB01217Anastrozole2Active Not Recruiting1
DB11595Atezolizumab2Recruiting1
DB00112Bevacizumab2Recruiting1
DB06616Bosutinib2Terminated1
DB15279CB-1032Active Not Recruiting1
DB09061Cannabidiol2Recruiting1
DB01101Capecitabine2Completed1
DB01101Capecitabine2Not Yet Recruiting2
DB01101Capecitabine2Recruiting1
DB01101Capecitabine2Terminated1
DB01101Capecitabine2Unknown Status1
DB12218Capivasertib2Recruiting1
DB04849Cediranib2Completed1
DB14917Ceralasertib2Recruiting1
DB00515Cisplatin2Unknown Status1
DB11672Curcumin2Completed1
DB00531Cyclophosphamide2Recruiting1
DB01254Dasatinib2Completed2
DB01234Dexamethasone2Completed1
DB01248Docetaxel2Completed1
DB00997Doxorubicin2Recruiting1
DB08899Enzalutamide2Active Not Recruiting1
DB01590Everolimus2Active Not Recruiting1
DB01590Everolimus2Completed1
DB00990Exemestane2Active Not Recruiting1
DB00990Exemestane2Completed1
DB00990Exemestane2Terminated1
DB11741Famitinib2Recruiting1
DB00947Fulvestrant2Completed4
DB00947Fulvestrant2Not Yet Recruiting1
DB00947Fulvestrant2Recruiting5
DB00441Gemcitabine2Active Not Recruiting1
DB00014Goserelin2Completed1
DB11743Ipatasertib2Not Yet Recruiting1
DB01259Lapatinib2Completed1
DB01259Lapatinib2Terminated1
DB12984Larotaxel2Completed1
DB16218Lerociclib2Recruiting1
DB01006Letrozole2Active Not Recruiting1
DB01006Letrozole2Recruiting2
DB14967Margetuximab2Not Yet Recruiting1
DB00218Moxifloxacin2Completed1
DB11828Neratinib2Completed1
DB11828Neratinib2Recruiting1
DB09074Olaparib2Active Not Recruiting1
DB09074Olaparib2Recruiting1
DB09074Olaparib2Terminated1
DB01229Paclitaxel2Completed1
DB01229Paclitaxel2Recruiting1
DB09073Palbociclib2Not Yet Recruiting1
DB09073Palbociclib2Recruiting1
DB09037Pembrolizumab2Active Not Recruiting1
DB06366Pertuzumab2Not Yet Recruiting1
DB14993Pyrotinib2Not Yet Recruiting2
DB11730Ribociclib2Not Yet Recruiting1
DB11760Talazoparib2Not Yet Recruiting1
DB11760Talazoparib2Recruiting2
DB00072Trastuzumab2Active Not Recruiting1
DB00072Trastuzumab2Completed1
DB00072Trastuzumab2Not Yet Recruiting2
DB00072Trastuzumab2Terminated1
DB14962Trastuzumab deruxtecan2Completed1
DB05773Trastuzumab emtansine2Not Yet Recruiting1
DB11652Tucatinib2Not Yet Recruiting2
DB05294Vandetanib2Completed1
DB00361Vinorelbine2Recruiting1
DB12015Alpelisib3Recruiting1
DB01217Anastrozole3Active Not Recruiting1
DB01217Anastrozole3Completed2
DB01217Anastrozole3Not Yet Recruiting1
DB01101Capecitabine3Recruiting1
DB01248Docetaxel3Withdrawn1
DB11841Entinostat3Active Not Recruiting1
DB08871Eribulin3Recruiting1
DB00990Exemestane3Active Not Recruiting1
DB00947Fulvestrant3Active Not Recruiting2
DB00947Fulvestrant3Completed2
DB00947Fulvestrant3Recruiting2
DB00441Gemcitabine3Completed1
DB00441Gemcitabine3Terminated1
DB01006Letrozole3Active Not Recruiting1
DB01006Letrozole3Not Yet Recruiting1
DB01229Paclitaxel3Completed1
DB01229Paclitaxel3Terminated1
DB06366Pertuzumab3Withdrawn1
DB11730Ribociclib3Active Not Recruiting1
DB00072Trastuzumab3Recruiting1
DB00072Trastuzumab3Withdrawn1
DB11641Vinflunine3Terminated1
DB00361Vinorelbine3Recruiting1
DB00361Vinorelbine3Withdrawn1
DB01217AnastrozoleNot AvailableCompleted1
DB08871EribulinNot AvailableUnknown Status1
DB00947FulvestrantNot AvailableRecruiting1
DB09073PalbociclibNot AvailableCompleted1
DB01268SunitinibNot AvailableCompleted1
DB06334TucidinostatNot AvailableRecruiting1