Angioneurotic Edema

Also known as: Angioneurotic oedema / Allergic angioedema / Allergic angioedema (disorder) / Angioedema (morphologic abnormality) / Oedema angioneurotic / Quincke's edema / Angioedema / Angioedema (disorder) / Angioedemas / Edema angioneurotic / Angioedema and urticaria / Angio-edema / Oedema Quincke's / Quincke's oedema / Giant urticaria / Edema Quincke's / Urticaria giant / Giant urticaria (disorder) / Giant hives / Hives giant

Drug	Drug Name	Drug Description
DB01114	Chlorpheniramine	A histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies.
DB00668	Epinephrine	A hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
DB14542	Hydrocortisone phosphate	A corticosteroid used to treat congenital adrenal hyperplasia, for emergency asthma treatment, hypersensitivity, and inflammation.

Drug	Drug Name	Target	Type
DB01114	Chlorpheniramine	Histamine H1 receptor	target
DB01114	Chlorpheniramine	Cytochrome P450 3A4	enzyme
DB01114	Chlorpheniramine	Cytochrome P450 2D6	enzyme
DB01114	Chlorpheniramine	Sodium-dependent serotonin transporter	target
DB01114	Chlorpheniramine	Sodium-dependent noradrenaline transporter	target
DB01114	Chlorpheniramine	Sodium-dependent dopamine transporter	target
DB01114	Chlorpheniramine	Cytochrome P450 3A5	enzyme
DB01114	Chlorpheniramine	Cytochrome P450 3A7	enzyme
DB01114	Chlorpheniramine	Solute carrier family 22 member 2	transporter
DB01114	Chlorpheniramine	Solute carrier family 22 member 1	transporter
DB00668	Epinephrine	Alpha-1A adrenergic receptor	target
DB00668	Epinephrine	Beta-1 adrenergic receptor	target
DB00668	Epinephrine	Beta-2 adrenergic receptor	target
DB00668	Epinephrine	Solute carrier family 22 member 2	transporter
DB00668	Epinephrine	Solute carrier family 22 member 1	transporter
DB00668	Epinephrine	Cytochrome P450 2C9	enzyme
DB00668	Epinephrine	Cytochrome P450 3A4	enzyme
DB00668	Epinephrine	Alpha-1B adrenergic receptor	target
DB00668	Epinephrine	Alpha-1D adrenergic receptor	target
DB00668	Epinephrine	Alpha-2A adrenergic receptor	target
DB00668	Epinephrine	Alpha-2B adrenergic receptor	target
DB00668	Epinephrine	Tumor necrosis factor	target
DB00668	Epinephrine	Catechol O-methyltransferase	enzyme
DB00668	Epinephrine	Monoamine oxidase	enzyme
DB14542	Hydrocortisone phosphate	Annexin A1	target
DB14542	Hydrocortisone phosphate	Glucocorticoid receptor	target
DB14542	Hydrocortisone phosphate	Sex hormone-binding globulin	carrier
DB14542	Hydrocortisone phosphate	Cytochrome P450 3A4	enzyme
DB14542	Hydrocortisone phosphate	Cytochrome P450 3A5	enzyme
DB14542	Hydrocortisone phosphate	Cytochrome P450 3A7	enzyme
DB14542	Hydrocortisone phosphate	P-glycoprotein 1	transporter
DB14542	Hydrocortisone phosphate	Solute carrier organic anion transporter family member 1A2	transporter
DB14542	Hydrocortisone phosphate	ATP-binding cassette sub-family G member 2	transporter
DB14542	Hydrocortisone phosphate	Cytochrome P450 2C8	enzyme
DB14542	Hydrocortisone phosphate	Corticosteroid-binding globulin	carrier
DB14542	Hydrocortisone phosphate	Corticosteroid 11-beta-dehydrogenase isozyme 2	target
DB14542	Hydrocortisone phosphate	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	target
DB14542	Hydrocortisone phosphate	Solute carrier family 22 member 8	transporter

Drug	Drug Name	Phase	Status	Count
DB06196	Icatibant	1	Terminated	1
DB06404	Human C1-esterase inhibitor	2	Completed	1
DB09228	Conestat alfa	2 / 3	Completed	1
DB09228	Conestat alfa	3	Completed	1