Peptic Ulcers

Also known as: Ulcer Peptic / Peptic Ulcer / Gastroduodenal ulcer / Ulcer gastroduodenal / Peptic ulcer, site unspecified / Peptic ulcer NOS / Peptic ulcer syndrome / Ulcer syndrome peptic / Peptic ulcer disease / Syndrome peptic ulcer / PUD / Peptic ulceration / GDU

DrugDrug NameDrug Description
DB00572AtropineA muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs.
DB00736EsomeprazoleA proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion.
DB00986GlycopyrroniumAn anticholinergic agent used to treat hyperhidrosis, severe drooling, COPD, used with other medications to treat ulcers, and used in anesthesia.
DB00424HyoscyamineAn anticholinergic indicated to treat functional gastrointestinal disorders, biliary and renal colic, and acute rhinitis.
DB08938MagaldrateAn antacid used to treat various conditions in the GI tract, such as esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux.
DB04843MepenzolateA postganglionic parasympathetic inhibitor that was previously approved for improving the healing of gastric ulcers, but has been discontinued.
DB00462Methscopolamine bromideA muscarinic antagonist used to treat peptic ulcers, nausea, vomiting, and motion sickness.
DB13844PipenzolateAn antimuscarinic agent indicated in the treatment of gastrointestinal motility disorders and arrhythmia.
DB00782PropanthelineAn antimuscarinic agent used to treat urinary incontinence, hyperhidrosis, as well as cramps and spasms of the stomach, intestines, and bladder.
DB09512SimethiconeAn anti-flatulence agent used to relieve pressure, bloating, and symptoms referred to as gas.
DB00364SucralfateA gastro-duodenal protective agent used in the treatment of gastric and duodenal ulcers and to prevent duodenal ulcer recurrence.
DrugDrug NameTargetType
DB00572AtropineMuscarinic acetylcholine receptor M2target
DB00572AtropineMuscarinic acetylcholine receptor M1target
DB00572AtropineMuscarinic acetylcholine receptor M4target
DB00572AtropineMuscarinic acetylcholine receptor M5target
DB00572AtropineMuscarinic acetylcholine receptor M3target
DB00572AtropineGlycine receptor subunit alpha-1target
DB00572AtropineNeuronal acetylcholine receptor subunit alpha-4target
DB00572AtropineNeuronal acetylcholine receptor subunit beta-2target
DB00572AtropineBile salt export pumptransporter
DB00736EsomeprazolePotassium-transporting ATPase alpha chain 1target
DB00736EsomeprazoleCytochrome P450 2C19enzyme
DB00736EsomeprazoleCytochrome P450 3A4enzyme
DB00736EsomeprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
DB00736EsomeprazoleP-glycoprotein 1transporter
DB00736EsomeprazoleSolute carrier family 22 member 8transporter
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M1target
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M3target
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M2target
DB00986GlycopyrroniumCytochrome P450 2D6enzyme
DB00986GlycopyrroniumCytochrome P450 1A2enzyme
DB00986GlycopyrroniumCytochrome P450 2B6enzyme
DB00986GlycopyrroniumCytochrome P450 2C9enzyme
DB00986GlycopyrroniumCytochrome P450 2C18enzyme
DB00986GlycopyrroniumCytochrome P450 2C19enzyme
DB00986GlycopyrroniumCytochrome P450 3A4enzyme
DB00986GlycopyrroniumSolute carrier family 22 member 2transporter
DB00986GlycopyrroniumMultidrug and toxin extrusion protein 1transporter
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M4target
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M5target
DB00986GlycopyrroniumSerum albumincarrier
DB00986Glycopyrroniumalpha1-acid glycoproteincarrier
DB00424HyoscyamineMuscarinic acetylcholine receptor M1target
DB00424HyoscyamineMuscarinic acetylcholine receptor M2target
DB00424HyoscyamineMuscarinic acetylcholine receptor M3target
DB00424HyoscyamineMuscarinic acetylcholine receptor M4target
DB00424HyoscyamineAdenylate cyclase type 1target
DB04843MepenzolateMuscarinic acetylcholine receptor M1target
DB04843MepenzolateMuscarinic acetylcholine receptor M3target
DB00462Methscopolamine bromideMuscarinic acetylcholine receptor M1target
DB00462Methscopolamine bromideMuscarinic acetylcholine receptor M2target
DB00462Methscopolamine bromideMuscarinic acetylcholine receptor M3target
DB00782PropanthelineMuscarinic acetylcholine receptor M1target
DB00364SucralfateFibrinogentarget
DB00364SucralfatePepsin A-5target
DB00364SucralfatePro-epidermal growth factortarget
DB00364SucralfateFibroblast growth factor 2target
DrugDrug NamePhaseStatusCount
DB13135AGN-2019041Completed1
DB00736Esomeprazole1Completed1
DB12770Lafutidine1Completed1
DB00758Clopidogrel2Completed1
DB00736Esomeprazole2Completed1
DB09099Somatostatin2Completed1
DB00571Propranolol2 / 3Terminated1
DB01129Rabeprazole2 / 3Terminated1
DB16078Abeprazan3Not Yet Recruiting1
DB00945Acetylsalicylic acid3Completed1
DB00482Celecoxib3Completed1
DB00736Esomeprazole3Completed1
DB05369HZT-5013Completed1
DB01050Ibuprofen3Completed1
DB11964Ilaprazole3Completed1
DB00448Lansoprazole3Completed1
DB00448Lansoprazole3Not Yet Recruiting1
DB00448Lansoprazole3Unknown Status1
DB00788Naproxen3Completed1
DB00338Omeprazole3Completed1
DB00213Pantoprazole3Completed3
DB00213Pantoprazole3Unknown Status2
DB00945Acetylsalicylic acid4Completed1
DB01060Amoxicillin4Completed6
DB01060Amoxicillin4Enrolling by Invitation1
DB00207Azithromycin4Completed1
DB04115Berberine4Completed2
DB00482Celecoxib4Completed1
DB01211Clarithromycin4Completed6
DB00736Esomeprazole4Completed3
DB00736Esomeprazole4Enrolling by Invitation1
DB00736Esomeprazole4Unknown Status1
DB00736Esomeprazole4Withdrawn1
DB00927Famotidine4Completed1
DB00614Furazolidone4Enrolling by Invitation1
DB11964Ilaprazole4Completed1
DB00448Lansoprazole4Completed4
DB00916Metronidazole4Completed2
DB00788Naproxen4Completed1
DB00338Omeprazole4Completed2
DB00338Omeprazole4Withdrawn1
DB00213Pantoprazole4Withdrawn1
DB09125Potassium citrate4Completed3
DB00863Ranitidine4Withdrawn1
DB00759Tetracycline4Enrolling by Invitation1
DB06723Aluminum hydroxideNot AvailableUnknown Status1
DB00668EpinephrineNot AvailableCompleted1
DB00927FamotidineNot AvailableCompleted2
DB05381HistamineNot AvailableCompleted2
DB14522Hydroxide ionNot AvailableUnknown Status1
DB00448LansoprazoleNot AvailableUnknown Status1
DB00213PantoprazoleNot AvailableCompleted1
DB00213PantoprazoleNot AvailableUnknown Status1