Moderate to Severe Atopic Dermatitis
Also known as: Moderate/Severe Atopic Dermatitis / Moderate-to-Severe Atopic Dermatiti / Moderate-to-severe Atopic Dermatitis
| Drug | Drug Name | Drug Description |
|---|---|---|
| DB12159 | Dupilumab | A monoclonal antibody used to treat moderate to severe atopic dermatitis, asthma, and nasal polyps accompanied by chronic rhinosinusitis in adolescents and adults. |
| DB11914 | Lebrikizumab | An IgG4 monoclonal antibody against IL-13 used to treat moderate-to-severe atopic dermatitis in adults and adolescents. |
| DB12169 | Tralokinumab | A monoclonal antibody directed against interleukin-13 which is used in the treatment of moderate-to-severe atopic dermatitis in patients requiring systemic therapy. |
| Drug | Drug Name | Target | Type |
|---|---|---|---|
| DB12159 | Dupilumab | Interleukin-4 receptor subunit alpha | target |
| DB12159 | Dupilumab | Interleukin-13 | target |
| DB12159 | Dupilumab | Interleukin-4 | target |
| DB11914 | Lebrikizumab | Interleukin-13 | target |
| DB12169 | Tralokinumab | Interleukin-13 | target |
| Drug | Drug Name | Phase | Status | Count |
|---|---|---|---|---|
| DB18990 | Stapokibart | 1 / 2 | Completed | 1 |
| DB15252 | Nemolizumab | 2 | Recruiting | 1 |
| DB18995 | Rademikibart | 2 | Completed | 2 |
| DB18992 | Rezpegaldesleukin | 2 | Recruiting | 1 |
| DB18990 | Stapokibart | 2 | Completed | 1 |
| DB18990 | Stapokibart | 2 | Recruiting | 1 |
| DB16374 | Telazorlimab | 2 | Completed | 1 |
| DB12159 | Dupilumab | 3 | Completed | 1 |
| DB00563 | Methotrexate | 3 | Recruiting | 1 |
| DB15252 | Nemolizumab | 3 | Active Not Recruiting | 1 |
| DB15252 | Nemolizumab | 3 | Completed | 2 |
| DB15252 | Nemolizumab | 3 | Withdrawn | 1 |
| DB18809 | Rocatinlimab | 3 | Active Not Recruiting | 1 |
| DB12159 | Dupilumab | 4 | Active Not Recruiting | 1 |
| DB00864 | Tacrolimus | 4 | Completed | 1 |
| DB00091 | Cyclosporine | Not Available | Completed | 1 |
| DB12159 | Dupilumab | Not Available | Completed | 1 |
| DB00337 | Pimecrolimus | Not Available | Completed | 1 |
| DB01130 | Prednicarbate | Not Available | Completed | 1 |
| DB00860 | Prednisolone | Not Available | Completed | 1 |
| DB00864 | Tacrolimus | Not Available | Completed | 1 |