Cataract Surgery

Also known as: Cataract operation / Surgery for Cataract / Cataract removal / Cataract Extraction / Lens operation (& cataract extraction) / Cataract extractions (procedure) / Cataract extractions / Extraction of cataract (procedure) / Cataract surgery specialty (qualifier value)

DrugDrug NameDrug Description
DB00963BromfenacAn NSAID used to treat postoperative pain and inflammation of the eye.
DB00411CarbamoylcholineA direct acting miotic agent administered ophthalmically to decrease intraocular pressure after cataract surgery, and to induce miosis during surgery.
DB01234DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
DB00586DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
DB00465KetorolacAn NSAID used to treat moderate to severe pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders, and headaches.
DB06802NepafenacAn ophthalmic NSAID used for the symptomatic treatment of pain and inflammation associated with cataract surgery.
DrugDrug NameTargetType
DB00963BromfenacProstaglandin G/H synthase 1target
DB00963BromfenacProstaglandin G/H synthase 2target
DB00963BromfenacProstaglandin G/H synthase 2enzyme
DB00411CarbamoylcholineMuscarinic acetylcholine receptor M1target
DB00411CarbamoylcholineMuscarinic acetylcholine receptor M2target
DB00411CarbamoylcholineNeuronal acetylcholine receptor subunit alpha-2target
DB00411CarbamoylcholineCytosolic phospholipase A2enzyme
DB00411CarbamoylcholineMuscarinic acetylcholine receptor M3target
DB00411CarbamoylcholineMuscarinic acetylcholine receptor M4target
DB00411CarbamoylcholineAcetylcholinesteraseenzyme
DB01234DexamethasoneGlucocorticoid receptortarget
DB01234DexamethasoneAnnexin A1target
DB01234DexamethasoneNitric oxide synthase, inducibletarget
DB01234DexamethasoneNuclear receptor subfamily 0 group B member 1target
DB01234DexamethasoneCytochrome P450 3A4enzyme
DB01234DexamethasoneCytochrome P450 3A5enzyme
DB01234DexamethasoneCytochrome P450 3A7enzyme
DB01234DexamethasoneBile salt export pumptransporter
DB01234DexamethasoneP-glycoprotein 1transporter
DB01234DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DB01234DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DB01234DexamethasoneATP-binding cassette sub-family G member 2transporter
DB01234DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01234DexamethasoneCytochrome P450 1A1enzyme
DB01234DexamethasoneCytochrome P450 2A6enzyme
DB01234DexamethasoneCytochrome P450 2B6enzyme
DB01234DexamethasoneCytochrome P450 2C19enzyme
DB01234DexamethasoneCytochrome P450 2C8enzyme
DB01234DexamethasoneCytochrome P450 2E1enzyme
DB01234DexamethasoneCytochrome P450 3A43enzyme
DB01234DexamethasoneCytochrome P450 4A11enzyme
DB01234DexamethasoneNuclear receptor subfamily 1 group I member 2target
DB01234DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DB01234DexamethasoneSerum albumincarrier
DB01234DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DB01234DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB01234DexamethasoneSolute carrier family 22 member 8transporter
DB00586DiclofenacProstaglandin G/H synthase 1target
DB00586DiclofenacProstaglandin G/H synthase 2target
DB00586DiclofenacTransthyretincarrier
DB00586DiclofenacCytochrome P450 2C9enzyme
DB00586DiclofenacCytochrome P450 2C19enzyme
DB00586DiclofenacCytochrome P450 1A2enzyme
DB00586DiclofenacCytochrome P450 2C8enzyme
DB00586DiclofenacSerum albumincarrier
DB00586DiclofenacMultidrug resistance-associated protein 4transporter
DB00586DiclofenacMultidrug resistance-associated protein 1transporter
DB00586DiclofenacSolute carrier family 22 member 6transporter
DB00586DiclofenacSolute carrier family 22 member 8transporter
DB00586DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DB00586DiclofenacSolute carrier family 22 member 11transporter
DB00586DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DB00586DiclofenacCytochrome P450 3A4enzyme
DB00586DiclofenacCytochrome P450 2B6enzyme
DB00586DiclofenacCytochrome P450 2C18enzyme
DB00586DiclofenacCytochrome P450 2E1enzyme
DB00586DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DB00586DiclofenacBile salt export pumptransporter
DB00586DiclofenacUDP-glucuronosyltransferase 1-3enzyme
DB00586DiclofenacUDP-glucuronosyltransferase 1-9enzyme
DB00586DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DB00586DiclofenacArachidonate 5-lipoxygenaseenzyme
DB00586DiclofenacSodium channel protein type 4 subunit alphatransporter
DB00586DiclofenacAcid-sensing ion channel 1transporter
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DB00586DiclofenacPhospholipase A2, membrane associatedenzyme
DB00586DiclofenacP-glycoprotein 1transporter
DB00465KetorolacProstaglandin G/H synthase 1target
DB00465KetorolacProstaglandin G/H synthase 2target
DB00465KetorolacUDP-glucuronosyltransferase 2B7enzyme
DB00465KetorolacCytochrome P450 2C8enzyme
DB00465KetorolacCytochrome P450 2C9enzyme
DB06802NepafenacProstaglandin G/H synthase 1target
DB06802NepafenacProstaglandin G/H synthase 2target
DrugDrug NamePhaseStatusCount
DB06771Besifloxacin1Completed1
DB01044Gatifloxacin1Completed1
DB00218Moxifloxacin1Completed1
DB00963Bromfenac2Completed1
DB12513Omaveloxolone2Completed1
DB01234Dexamethasone2 / 3Withdrawn1
DB15566Prednisolone acetate2 / 3Withdrawn1
DB01234Dexamethasone3Completed1
DB00465Ketorolac3Completed2
DB01137Levofloxacin3Completed1
DB00218Moxifloxacin3Not Yet Recruiting1
DB00955Netilmicin3Completed1
DB00512Vancomycin3Not Yet Recruiting1
DB00207Azithromycin4Completed1
DB06771Besifloxacin4Completed2
DB01234Dexamethasone4Not Yet Recruiting1
DB01234Dexamethasone4Recruiting1
DB01044Gatifloxacin4Completed1
DB00465Ketorolac4Completed2
DB00465Ketorolac4Recruiting1
DB01137Levofloxacin4Completed1
DB14596Loteprednol etabonate4Completed1
DB14596Loteprednol etabonate4Unknown Status1
DB00218Moxifloxacin4Completed5
DB06802Nepafenac4Completed1
DB00388Phenylephrine4Recruiting1
DB15566Prednisolone acetate4Completed2
DB15566Prednisolone acetate4Recruiting1
DB00620Triamcinolone4Terminated1
DB00484BrimonidineNot AvailableCompleted1
DB00297BupivacaineNot AvailableNot Yet Recruiting1
DB00979CyclopentolateNot AvailableRecruiting1
DB15919DiquafosolNot AvailableCompleted1
DB08818Hyaluronic acidNot AvailableCompleted1
DB00281LidocaineNot AvailableNot Yet Recruiting1
DB00410MupirocinNot AvailableCompleted1
DB01270RanibizumabNot AvailableRecruiting1
DB01236SevofluraneNot AvailableCompleted1