Hereditary Angioedema (HAE)

Also known as: Hereditary Angioedema, HAE / Angioedema, Hereditary / Angioedemas, Hereditary / Hereditary Angioedema / Hereditary angioedema C1 inhibitor deficiency / Hereditary angioneurotic edema (disorder) / C1 esterase inhibitor deficiency

DrugDrug NameDrug Description
DB01406DanazolA synthetic steroid and pituitary gonadotropin inhibitor used in the treatment of endometriosis and symptomatic treatment of severe pain and tenderness associated with benign fibrocystic breasts.
DB14597LanadelumabA plasma kallikrein inhibitor used to treat attacks of hereditary angioedema.
DB06718StanozololAn anabolic steroid used to manage hereditary angioedema.
DB00302Tranexamic acidAn antifibrinolytic used to reduce or prevent hemorrhagic episodes, especially in the context of hyperfibrinolytic disorders.
DrugDrug NamePhaseStatusCount
DB12120Avoralstat1Completed2
DB15982Berotralstat1Completed4
DB00091Cyclosporine1Completed1
DB00390Digoxin1Completed1
DB06196Icatibant1Completed1
DB14597Lanadelumab1Completed2
DB01098Rosuvastatin1Completed1
DB12120Avoralstat2Completed1
DB15982Berotralstat2Completed2
DB09228Conestat alfa2Completed3
DB05311Ecallantide2Completed1
DB15629Garadacimab2Active Not Recruiting1
DB06404Human C1-esterase inhibitor2Completed4
DB06205Hyaluronidase (human recombinant)2Completed2
DB12120Avoralstat2 / 3Completed1
DB15982Berotralstat2 / 3Active Not Recruiting1
DB09228Conestat alfa2 / 3Completed1
DB05311Ecallantide2 / 3Withdrawn1
DB06404Human C1-esterase inhibitor2 / 3Completed1
DB06404Human C1-esterase inhibitor2 / 3Not Yet Recruiting1
DB12120Avoralstat3Terminated1
DB15982Berotralstat3Active Not Recruiting2
DB15982Berotralstat3Not Yet Recruiting1
DB09228Conestat alfa3Completed1
DB05311Ecallantide3Completed3
DB15629Garadacimab3Recruiting2
DB06404Human C1-esterase inhibitor3Completed4
DB06196Icatibant3Completed6
DB14597Lanadelumab3Active Not Recruiting1
DB14597Lanadelumab3Completed3
DB14597Lanadelumab3Recruiting1
DB00302Tranexamic acid3Completed1
DB06404Human C1-esterase inhibitor4Completed1
DB06196Icatibant4Completed1
DB15982BerotralstatNot AvailableApproved for Marketing1
DB09228Conestat alfaNot AvailableRecruiting2
DB05311EcallantideNot AvailableCompleted1
DB06196IcatibantNot AvailableRecruiting1
DB14597LanadelumabNot AvailableAvailable1