Narcolepsy With Cataplexy

Also known as: Cataplexy Narcolepsy / Narcolepsy-cataplexy / Narcolepsy and cataplexy / Cataplexy and narcolepsy (disorder) / Narcolepsy-Cataplexy Syndrome / Cataplexy and narcolepsy / Cataplexy or narcolepsy NOS (disorder) / Narcolepsy / Narcolepsy without cataplexy / (CNS disorders NOS) or (narcolepsy) or (Ondine's curse) or (Schilder's disease) / Narcolepsy (disorder)

Drug	Drug Name	Drug Description
DB11642	Pitolisant	An antagonist and inverse agonist at the histamine H3 receptor that is used to treat narcolepsy in adults.

Drug	Drug Name	Target	Type
DB11642	Pitolisant	Histamine H3 receptor	target
DB11642	Pitolisant	Cytochrome P450 3A4	enzyme
DB11642	Pitolisant	Cytochrome P450 2D6	enzyme
DB11642	Pitolisant	Cytochrome P450 1A2	enzyme
DB11642	Pitolisant	Cytochrome P450 2B6	enzyme
DB11642	Pitolisant	Solute carrier family 22 member 1	transporter
DB11642	Pitolisant	Potassium voltage-gated channel subfamily H member 2	target
DB11642	Pitolisant	Serum albumin	carrier
DB11642	Pitolisant	Alpha-1-acid glycoprotein 1	carrier

Drug	Drug Name	Phase	Status	Count
DB09072	Sodium oxybate	1	Completed	1
DB01211	Clarithromycin	2	Recruiting	1
DB00579	Mazindol	2	Completed	2
DB00234	Reboxetine	2	Completed	1
DB00579	Mazindol	3	Not Yet Recruiting	1
DB11642	Pitolisant	3	Active Not Recruiting	1
DB11642	Pitolisant	3	Completed	1
DB09072	Sodium oxybate	3	Completed	2
DB09072	Sodium oxybate	4	Completed	1
DB01440	gamma-Hydroxybutyric acid	4	Completed	1
DB11642	Pitolisant	Not Available	No Longer Available	1