Relapsed Or Refractory Multiple Myeloma

Also known as: Relapsed and/or Refractory Multiple Myeloma (RRMM) / Relapsed, Refractory, Multiple Myeloma / Relapse or Refractory Multiple Myeloma / Relapse and/or Refractory Multiple Myeloma / Relapsed/Refractory Multiple Myeloma (RRMM) / Relapsed and Refractory Multiple Myeloma / Relapsed/Refractory Multiple Myeloma(MM) / Relapsed, Refractory Multiple Myeloma / Relapsed/ Refractory Multiple Myeloma / Relapsed/Refractory Multiple Myeloma / Relapsed and/or Refractory Multiple Myeloma / Relapsed and/or Relapsed-refractory Multiple Myeloma / Refractory or Relapsed Multiple Myeloma / Relapsed Refractory Multiple Myeloma / Refractory, relapsed Multiple Myeloma / Plasma cell myeloma refractory

Drug	Drug Name	Drug Description
DB15719	Belantamab mafodotin	An anti B-cell maturation antigen antibody conjugated to a microtubule inhibitor to treat relapsed or refractory multiple myeloma.
DB08889	Carfilzomib	A proteasome inhibitor used either alone or in conjunction with a chemotherapy regimen to treat patients with relapsed or refractory multiple myeloma.
DB16627	Melphalan flufenamide	A melphalan prodrug used to treat relapsed or refractory multiple myeloma.

Drug	Drug Name	Target	Type
DB15719	Belantamab mafodotin	Solute carrier organic anion transporter family member 1B1	transporter
DB15719	Belantamab mafodotin	Solute carrier organic anion transporter family member 1B3	transporter
DB15719	Belantamab mafodotin	Multidrug resistance-associated protein 1	transporter
DB15719	Belantamab mafodotin	Canalicular multispecific organic anion transporter 1	transporter
DB15719	Belantamab mafodotin	Canalicular multispecific organic anion transporter 2	transporter
DB15719	Belantamab mafodotin	Bile salt export pump	transporter
DB15719	Belantamab mafodotin	P-glycoprotein 1	transporter
DB15719	Belantamab mafodotin	Tumor necrosis factor receptor superfamily member 17	target
DB08889	Carfilzomib	P-glycoprotein 1	transporter
DB08889	Carfilzomib	Proteasome subunit beta type-5	target
DB08889	Carfilzomib	Proteasome subunit beta type-9	target
DB08889	Carfilzomib	Proteasome subunit beta type-10	target
DB08889	Carfilzomib	Proteasome subunit beta type-8	target
DB08889	Carfilzomib	Proteasome subunit beta type-1	target
DB08889	Carfilzomib	Proteasome subunit beta type-2	target
DB16627	Melphalan flufenamide	Aminopeptidase N	enzyme
DB16627	Melphalan flufenamide	DNA	target

Drug	Drug Name	Phase	Status	Count
DB00531	Cyclophosphamide	0	Recruiting	1
DB01073	Fludarabine	0	Recruiting	1
DB17357	AMG 424	1	Terminated	1
DB12015	Alpelisib	1	Completed	1
DB00098	Antithymocyte immunoglobulin (rabbit)	1	Active Not Recruiting	1
DB00098	Antithymocyte immunoglobulin (rabbit)	1	Completed	1
DB00928	Azacitidine	1	Completed	1
DB00928	Azacitidine	1	Recruiting	1
DB00188	Bortezomib	1	Completed	1
DB00188	Bortezomib	1	Recruiting	1
DB00188	Bortezomib	1	Withdrawn	1
DB16741	Bortezomib D-mannitol	1	Recruiting	1
DB16874	CB-5083	1	Terminated	1
DB00631	Clofarabine	1	Active Not Recruiting	1
DB00531	Cyclophosphamide	1	Active Not Recruiting	1
DB00531	Cyclophosphamide	1	Recruiting	3
DB00531	Cyclophosphamide	1	Terminated	1
DB00531	Cyclophosphamide	1	Withdrawn	1
DB09331	Daratumumab	1	Recruiting	1
DB01234	Dexamethasone	1	Active Not Recruiting	1
DB01234	Dexamethasone	1	Completed	4
DB01234	Dexamethasone	1	Recruiting	2
DB01234	Dexamethasone	1	Terminated	2
DB01234	Dexamethasone	1	Withdrawn	1
DB01073	Fludarabine	1	Active Not Recruiting	1
DB01073	Fludarabine	1	Recruiting	3
DB01073	Fludarabine	1	Terminated	1
DB17251	ISB 1342	1	Recruiting	1
DB16479	Inbakicept	1	Unknown Status	1
DB01167	Itraconazole	1	Recruiting	1
DB09570	Ixazomib	1	Completed	2
DB09570	Ixazomib	1	Terminated	1
DB14943	LGH-447	1	Completed	1
DB00480	Lenalidomide	1	Completed	1
DB00480	Lenalidomide	1	Recruiting	1
DB00480	Lenalidomide	1	Terminated	1
DB17430	MT-0169	1	Recruiting	1
DB01204	Mitoxantrone	1	Recruiting	1
DB16399	Modakafusp alfa	1	Withdrawn	1
DB12005	Nirogacestat	1	Recruiting	2
DB15395	PF-06863135	1	Active Not Recruiting	1
DB17254	Pacanalotamab	1	Completed	1
DB08910	Pomalidomide	1	Active Not Recruiting	1
DB08910	Pomalidomide	1	Completed	1
DB08910	Pomalidomide	1	Recruiting	1
DB08910	Pomalidomide	1	Withdrawn	1
DB17556	S65487	1	Active Not Recruiting	1
DB11942	Selinexor	1	Completed	1
DB16678	Talquetamab	1	Recruiting	1
DB17166	Tapotoclax	1	Recruiting	1
DB16655	Teclistamab	1	Recruiting	1
DB11581	Venetoclax	1	Completed	1
DB02546	Vorinostat	1	Completed	1
DB15386	ALT-801	1 / 2	Terminated	1
DB11881	AUY922	1 / 2	Completed	1
DB12001	Abemaciclib	1 / 2	Recruiting	1
DB15719	Belantamab mafodotin	1 / 2	Recruiting	3
DB06769	Bendamustine	1 / 2	Not Yet Recruiting	1
DB00188	Bortezomib	1 / 2	Completed	1
DB00188	Bortezomib	1 / 2	Withdrawn	1
DB15286	CB-1158	1 / 2	Terminated	1
DB05153	Cabozantinib	1 / 2	Completed	1
DB08875	Cabozantinib	1 / 2	Completed	1
DB08875	Cabozantinib	1 / 2	Terminated	1
DB08889	Carfilzomib	1 / 2	Recruiting	1
DB08889	Carfilzomib	1 / 2	Terminated	1
DB05239	Cobimetinib	1 / 2	Recruiting	1
DB00531	Cyclophosphamide	1 / 2	Completed	1
DB00531	Cyclophosphamide	1 / 2	Recruiting	2
DB09331	Daratumumab	1 / 2	Recruiting	2
DB09331	Daratumumab	1 / 2	Terminated	1
DB09331	Daratumumab	1 / 2	Withdrawn	1
DB01234	Dexamethasone	1 / 2	Completed	2
DB01234	Dexamethasone	1 / 2	Not Yet Recruiting	2
DB01234	Dexamethasone	1 / 2	Recruiting	6
DB01234	Dexamethasone	1 / 2	Terminated	2
DB01234	Dexamethasone	1 / 2	Withdrawn	1
DB06317	Elotuzumab	1 / 2	Not Yet Recruiting	1
DB06317	Elotuzumab	1 / 2	Recruiting	1
DB16153	Eltanexor	1 / 2	Recruiting	1
DB13874	Enasidenib	1 / 2	Recruiting	1
DB12147	Erdafitinib	1 / 2	Recruiting	1
DB01073	Fludarabine	1 / 2	Completed	1
DB01073	Fludarabine	1 / 2	Recruiting	1
DB14740	Hyaluronidase	1 / 2	Recruiting	1
DB06186	Ipilimumab	1 / 2	Terminated	1
DB09570	Ixazomib	1 / 2	Recruiting	1
DB00480	Lenalidomide	1 / 2	Terminated	1
DB16627	Melphalan flufenamide	1 / 2	Terminated	1
DB16370	Mezagitamab	1 / 2	Recruiting	1
DB12005	Nirogacestat	1 / 2	Completed	1
DB01229	Paclitaxel	1 / 2	Terminated	1
DB08910	Pomalidomide	1 / 2	Not Yet Recruiting	2
DB08910	Pomalidomide	1 / 2	Recruiting	3
DB08910	Pomalidomide	1 / 2	Withdrawn	1
DB14851	Relatlimab	1 / 2	Not Yet Recruiting	1
DB14851	Relatlimab	1 / 2	Recruiting	1
DB11942	Selinexor	1 / 2	Recruiting	1
DB16406	Subasumstat	1 / 2	Recruiting	1
DB11581	Venetoclax	1 / 2	Completed	1
DB11581	Venetoclax	1 / 2	Recruiting	1
DB11967	Binimetinib	2	Active Not Recruiting	1
DB00188	Bortezomib	2	Completed	1
DB16741	Bortezomib D-mannitol	2	Completed	1
DB05147	CYT997	2	Terminated	1
DB08889	Carfilzomib	2	Active Not Recruiting	1
DB08889	Carfilzomib	2	Recruiting	1
DB08889	Carfilzomib	2	Terminated	1
DB08889	Carfilzomib	2	Unknown Status	1
DB00531	Cyclophosphamide	2	Completed	3
DB09331	Daratumumab	2	Recruiting	1
DB01234	Dexamethasone	2	Active Not Recruiting	1
DB01234	Dexamethasone	2	Completed	6
DB01234	Dexamethasone	2	Not Yet Recruiting	2
DB01234	Dexamethasone	2	Recruiting	2
DB01234	Dexamethasone	2	Terminated	1
DB01234	Dexamethasone	2	Unknown Status	1
DB05928	Dovitinib	2	Completed	1
DB06317	Elotuzumab	2	Completed	1
DB11718	Encorafenib	2	Active Not Recruiting	1
DB06205	Hyaluronidase (human recombinant)	2	Recruiting	1
DB14811	Isatuximab	2	Recruiting	1
DB09570	Ixazomib	2	Completed	2
DB09570	Ixazomib	2	Not Yet Recruiting	1
DB09570	Ixazomib	2	Recruiting	1
DB00480	Lenalidomide	2	Completed	1
DB08910	Pomalidomide	2	Active Not Recruiting	1
DB08910	Pomalidomide	2	Completed	3
DB08910	Pomalidomide	2	Not Yet Recruiting	1
DB08910	Pomalidomide	2	Recruiting	1
DB11942	Selinexor	2	Not Yet Recruiting	1
DB01041	Thalidomide	2	Completed	1
DB01041	Thalidomide	2	Unknown Status	1
DB11581	Venetoclax	2	Not Yet Recruiting	1
DB02546	Vorinostat	2	Completed	1
DB15719	Belantamab mafodotin	3	Withdrawn	1
DB00188	Bortezomib	3	Completed	1
DB00188	Bortezomib	3	Recruiting	3
DB16741	Bortezomib D-mannitol	3	Recruiting	1
DB08889	Carfilzomib	3	Active Not Recruiting	1
DB08889	Carfilzomib	3	Completed	1
DB08889	Carfilzomib	3	Recruiting	2
DB09331	Daratumumab	3	Recruiting	1
DB01234	Dexamethasone	3	Active Not Recruiting	1
DB01234	Dexamethasone	3	Completed	4
DB01234	Dexamethasone	3	Recruiting	5
DB00480	Lenalidomide	3	Active Not Recruiting	1
DB00480	Lenalidomide	3	Completed	1
DB04977	Plitidepsin	3	Completed	1
DB08910	Pomalidomide	3	Recruiting	3
DB11942	Selinexor	3	Recruiting	1
DB16678	Talquetamab	3	Recruiting	1
DB16678	Talquetamab	3	Withdrawn	1
DB16655	Teclistamab	3	Recruiting	1
DB11581	Venetoclax	3	Completed	1
DB00188	Bortezomib	4	Completed	1
DB08889	Carfilzomib	4	Active Not Recruiting	1
DB08889	Carfilzomib	4	Completed	1
DB01234	Dexamethasone	4	Active Not Recruiting	1
DB01234	Dexamethasone	4	Completed	1
DB09570	Ixazomib	4	Completed	1
DB00480	Lenalidomide	4	Active Not Recruiting	1
DB00480	Lenalidomide	4	Completed	1
DB15719	Belantamab mafodotin	Not Available	Recruiting	1
DB00531	Cyclophosphamide	Not Available	Active Not Recruiting	1
DB01234	Dexamethasone	Not Available	Approved for Marketing	1
DB01234	Dexamethasone	Not Available	Completed	1
DB01234	Dexamethasone	Not Available	Unknown Status	1
DB01073	Fludarabine	Not Available	Active Not Recruiting	1
DB09570	Ixazomib	Not Available	Completed	2
DB09570	Ixazomib	Not Available	Unknown Status	1
DB00480	Lenalidomide	Not Available	Completed	1
DB00480	Lenalidomide	Not Available	Unknown Status	1
DB16627	Melphalan flufenamide	Not Available	Approved for Marketing	1
DB16678	Talquetamab	Not Available	No Longer Available	1
DB16655	Teclistamab	Not Available	Approved for Marketing	1