Cardiovascular Risk

Also known as: Cardiovascular Disease Risk Factor / Risk Factor, Cardiovascular / Cardiovascular Factor Risk / Cardiovascular Risk Factors / Cardiovascular Risk Factor / Cardiovascular Disease (CVD) Risk Factors / Cardiovascular Disease Risk Factors / Risk Factors Cardiovascular Disease / Cardiovascular Disease Risk / Cardiovascular Diseases Risk / Cardiovascular (CV) Risk / Cardiovascular Risks / Disease risk factor

DrugDrug NameDrug Description
DB00945Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
DB01076AtorvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
DB09045DulaglutideA GLP-1 agonist used to manage type 2 diabetes mellitus.
DrugDrug NameTargetType
DB00945Acetylsalicylic acidProstaglandin G/H synthase 1target
DB00945Acetylsalicylic acidProstaglandin G/H synthase 2target
DB00945Acetylsalicylic acidAldo-keto reductase family 1 member C1target
DB00945Acetylsalicylic acidSolute carrier family 22 member 6transporter
DB00945Acetylsalicylic acidP-glycoprotein 1transporter
DB00945Acetylsalicylic acidCytochrome P450 2C19enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C9enzyme
DB00945Acetylsalicylic acid5'-AMP-activated protein kinasetarget
DB00945Acetylsalicylic acidEndothelin-1 receptortarget
DB00945Acetylsalicylic acidCellular tumor antigen p53target
DB00945Acetylsalicylic acid78 kDa glucose-regulated proteintarget
DB00945Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
DB00945Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
DB00945Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
DB00945Acetylsalicylic acidCaspase-1target
DB00945Acetylsalicylic acidCaspase-3target
DB00945Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00945Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
DB00945Acetylsalicylic acidG1/S-specific cyclin-D1target
DB00945Acetylsalicylic acidMyc proto-oncogene proteintarget
DB00945Acetylsalicylic acidProliferating cell nuclear antigentarget
DB00945Acetylsalicylic acidCyclin Atarget
DB00945Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
DB00945Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
DB00945Acetylsalicylic acidSolute carrier family 22 member 8transporter
DB01076Atorvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB01076AtorvastatinCytochrome P450 3A4enzyme
DB01076AtorvastatinDipeptidyl peptidase 4target
DB01076AtorvastatinCytochrome P450 2D6enzyme
DB01076AtorvastatinCytochrome P450 2C9enzyme
DB01076AtorvastatinCytochrome P450 2C19enzyme
DB01076AtorvastatinCytochrome P450 3A5enzyme
DB01076AtorvastatinCytochrome P450 3A7enzyme
DB01076AtorvastatinP-glycoprotein 1transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 1A2transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 1B1transporter
DB01076AtorvastatinMultidrug resistance-associated protein 4transporter
DB01076AtorvastatinMultidrug resistance-associated protein 5transporter
DB01076AtorvastatinMultidrug resistance-associated protein 1transporter
DB01076AtorvastatinCytochrome P450 2B6enzyme
DB01076AtorvastatinCytochrome P450 2C8enzyme
DB01076AtorvastatinAryl hydrocarbon receptortarget
DB01076AtorvastatinSolute carrier organic anion transporter family member 2B1transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 1B3transporter
DB01076AtorvastatinUDP-glucuronosyltransferase 1-1enzyme
DB01076AtorvastatinUDP-glucuronosyltransferase 1-3enzyme
DB01076AtorvastatinCanalicular multispecific organic anion transporter 1transporter
DB01076AtorvastatinBile salt export pumptransporter
DB01076AtorvastatinSerum albumincarrier
DB01076AtorvastatinHistone deacetylase 2target
DB01076AtorvastatinNuclear receptor subfamily 1 group I member 3target
DB09045DulaglutideGlucagon-like peptide 1 receptortarget
DrugDrug NamePhaseStatusCount
DB12301Doravirine0Not Yet Recruiting1
DB00470Dronabinol0Not Yet Recruiting1
DB00879Emtricitabine0Not Yet Recruiting1
DB14009Medical Cannabis0Not Yet Recruiting1
DB09299Tenofovir alafenamide0Not Yet Recruiting1
DB00437Allopurinol1Completed3
DB12618Apocynin1Completed3
DB00125Arginine1Recruiting1
DB00126Ascorbic acid1Recruiting1
DB12054BQ-1231Recruiting1
DB01164Calcium chloride1Recruiting1
DB01136Carvedilol1Recruiting1
DB14547Chloride ion1Completed1
DB04398Lactic acid1Recruiting1
DB12750N-omega-nitro-L-arginine methyl ester1Completed1
DB12750N-omega-nitro-L-arginine methyl ester1Recruiting2
DB00325Nitroprusside1Completed1
DB00325Nitroprusside1Recruiting1
DB00368Norepinephrine1Recruiting1
DB00388Phenylephrine1Completed1
DB00761Potassium chloride1Recruiting1
DB00360Sapropterin1Completed1
DB09153Sodium chloride1Recruiting1
DB12449Tempol1Completed2
DB00945Acetylsalicylic acid2Recruiting1
DB01076Atorvastatin2Recruiting1
DB06292Dapagliflozin2Recruiting1
DB11228Methylcellulose2Unknown Status1
DB00435Nitric Oxide2Recruiting1
DB12290Puerarin2Completed1
DB04115Berberine2 / 3Completed1
DB09061Cannabidiol2 / 3Recruiting1
DB01076Atorvastatin3Active Not Recruiting1
DB14901Inclisiran3Completed1
DB00583Levocarnitine3Active Not Recruiting1
DB00922Levosimendan3Recruiting1
DB11062Octisalate3Active Not Recruiting1
DB09535Octocrylene3Active Not Recruiting1
DB09321Zinc oxide3Active Not Recruiting1
DB00284Acarbose4Completed1
DB00945Acetylsalicylic acid4Completed1
DB00381Amlodipine4Recruiting1
DB11672Curcumin4Unknown Status1
DB09038Empagliflozin4Recruiting1
DB00977Ethinylestradiol4Completed1
DB00222Glimepiride4Recruiting1
DB08887Icosapent ethyl4Recruiting1
DB04835Maraviroc4Completed1
DB00563Methotrexate4Recruiting1
DB00957Norgestimate4Completed1
DB00715Paroxetine4Completed1
DB08860Pitavastatin4Completed1
DB01098Rosuvastatin4Completed1
DB01098Rosuvastatin4Not Yet Recruiting1
DB01098Rosuvastatin4Recruiting1
DB00641Simvastatin4Withdrawn1
DB11325Soy sterol4Not Yet Recruiting1
DB00795Sulfasalazine4Recruiting1
DB00758ClopidogrelNot AvailableCompleted1
DB00973EzetimibeNot AvailableCompleted1
DB01592IronNot AvailableRecruiting1
DB00722LisinoprilNot AvailableCompleted1
DB01024Mycophenolic acidNot AvailableNot Yet Recruiting1
DB00184NicotineNot AvailableUnknown Status1
DB12930OpipramolNot AvailableEnrolling by Invitation1
DB06209PrasugrelNot AvailableCompleted1
DB00175PravastatinNot AvailableCompleted1
DB00641SimvastatinNot AvailableCompleted1
DB02772SucroseNot AvailableRecruiting1
DB00864TacrolimusNot AvailableNot Yet Recruiting1
DB08816TicagrelorNot AvailableCompleted1