Skin Infections

Also known as: Skin Structure Infections / Skin-structure infections / Minor skin infection / Skin Infection / Infections of the skin and subcutaneous tissue (L00-L08) / Infected: [sebaceous cyst] or [skin and subcut tissue NOS] / Skin and subcut tissue infection NOS (disorder) / Infective dermatological disorders / [X]Infections of the skin and subcutaneous tissue (disorder) / (Skin infections NOS) or (perleche) / Infection of skin and/or subcutaneous tissue (disorder) / Skin infection NOS / Skin Diseases, Infectious / Infection of skin (disorder)

DrugDrug NameDrug Description
DB13373AcriflavineA topical antiseptic indicated in the treatment of infected wounds and for skin disinfection.
DB11561AminacrineA slow-acting germicide effective against bacteria and fungi which is included in drug formulations for its anti-septic properties.
DB00355AztreonamA beta-lactam antibiotic used to treat select aztreonam sensitive gram negative bacteria.
DB11482Balsam of PeruBalsam of Peru is found in diverse cosmetics and perfumes as well as a flavoring agent in cough syrups, lozenges, chewing gum, and candies. As a medical agent, balsam of...
DB00443BetamethasoneA systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
DB00878ChlorhexidineAn antiseptic used to sterilize for surgeries and in healthcare practice, to reduce pocket depth in periodontitis, and to treat gingivitis.
DB01243ChloroxineAn antibacterial agent used for the treatment of dandruff and mild to moderately severe seborrheic dermatitis of the scalp.
DB11121ChloroxylenolAn antimicrobial used to treat cuts, bites, stings, abrasions, and used as an antiseptic hand cleaner.
DB13306ChlorquinaldolChlorquinaldol was used historically as a topical antiseptic agent for skin infections. It maintains use in European countries as a combination vaginal tablet with promestriene for use in the treatment...
DB00537CiprofloxacinA second generation fluoroquinolone used to treat various susceptible bacterial infections.
DB04815ClioquinolAn antifungal cream used to treat a variety of fungal infections.
DB00257ClotrimazoleA topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
DB00254DoxycyclineA tetracycline antibiotic used to treat a wide variety of bacterial infections.
DB00798GentamicinAn aminoglycoside used to treat a wide variety of aerobic infections in the body.
DB09462GlycerinIt is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.
DB11254HexylresorcinolAn ingredient used to relieve irritation, pain, and prevent infection.
DB14112Human vaccinia virus immune globulinA purified gamma globulin used to treat vaccinia infections where skin is compromised, or infections of the eyes, mouth, or other areas where vaccinia infections present a special hazard.
DB14539Hydrocortisone acetateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses and ulcerative colitis.
DB14512Mometasone furoateA corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus.
DB00218MoxifloxacinA fluoroquinolone antibiotic used to treat various bacterial infections.
DB00994NeomycinAn aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body.
DB00336NitrofuralA topical antibacterial for the prevention and treatment of bacterial infections of the skin.
DB00595OxytetracyclineA tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections.
DB06812Povidone-iodineA topical antiseptic agent used for the treatment and prevention of infection in wounds.
DB00778RoxithromycinAn antibiotic used to treat a variety of susceptible bacterial infections.
DB13503TyrothricinA topical antibiotic with broad spectrum activity against Gram positive bacteria and some fungal infections.
DrugDrug NameTargetType
DB00355AztreonamPenicillin-binding protein 3target
DB00355AztreonamBeta-lactamasetarget
DB00443BetamethasoneGlucocorticoid receptortarget
DB00443BetamethasoneCytochrome P450 3A4enzyme
DB00443BetamethasoneP-glycoprotein 1transporter
DB00443BetamethasoneCytochrome P450 19A1enzyme
DB00443BetamethasoneCytochrome P450 3A5enzyme
DB00443BetamethasoneCytochrome P450 3A7enzyme
DB00443BetamethasoneCytochrome P450 2A6enzyme
DB00443BetamethasoneCytochrome P450 1B1enzyme
DB00443BetamethasoneCytochrome P450 2B6enzyme
DB00443BetamethasoneCytochrome P450 2C8enzyme
DB00443BetamethasoneCytochrome P450 2C9enzyme
DB00443BetamethasoneCytochrome P450 2C19enzyme
DB00443BetamethasoneSerum albumincarrier
DB00443BetamethasoneCorticosteroid-binding globulincarrier
DB00878ChlorhexidineBacterial outer membranetarget
DB00878ChlorhexidineSerum albumincarrier
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 2-alphatarget
DB00537CiprofloxacinCytochrome P450 1A2enzyme
DB00537CiprofloxacinCytochrome P450 3A4enzyme
DB00537CiprofloxacinCytochrome P450 3A5enzyme
DB00537CiprofloxacinCytochrome P450 3A7enzyme
DB00537CiprofloxacinP-glycoprotein 1transporter
DB00537CiprofloxacinPotassium voltage-gated channel subfamily H member 2target
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Btarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinMultidrug resistance protein MdtKtarget
DB00537CiprofloxacinGyrase Atarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinMultidrug and toxin extrusion protein 1transporter
DB00537CiprofloxacinMultidrug and toxin extrusion protein 2transporter
DB00537CiprofloxacinSerum albumincarrier
DB00257ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
DB00257ClotrimazoleCytochrome P450 2D6enzyme
DB00257ClotrimazoleCytochrome P450 2C8enzyme
DB00257ClotrimazoleCytochrome P450 3A4enzyme
DB00257ClotrimazoleCytochrome P450 2B6enzyme
DB00257ClotrimazoleP-glycoprotein 1transporter
DB00257ClotrimazoleCytochrome P450 2A6enzyme
DB00257ClotrimazoleCytochrome P450 2C9enzyme
DB00257ClotrimazoleCytochrome P450 2E1enzyme
DB00257ClotrimazoleCytochrome P450 3A7enzyme
DB00257ClotrimazoleCytochrome P450 51target
DB00257ClotrimazoleNuclear receptor subfamily 1 group I member 2target
DB00257ClotrimazoleHydroxycarboxylic acid receptor 2target
DB00257ClotrimazoleBile salt export pumptransporter
DB00257ClotrimazoleSolute carrier organic anion transporter family member 1B1transporter
DB00257ClotrimazoleSolute carrier organic anion transporter family member 1B3transporter
DB00257ClotrimazoleErgosteroltarget
DB00254Doxycycline16S ribosomal RNAtarget
DB00254DoxycyclineSolute carrier family 22 member 6transporter
DB00254DoxycyclineCytochrome P450 3A4enzyme
DB00254DoxycyclineATP-binding cassette sub-family B member 5transporter
DB00798Gentamicin30S ribosomal protein S12target
DB00798Gentamicin16S ribosomal RNAtarget
DB00798GentamicinNH(3)-dependent NAD(+) synthetasetarget
DB00798GentamicinDihydrofolate reductasetarget
DB00798Gentamicin23S ribosomal RNAtarget
DB00798GentamicinBacterial outer membranetarget
DB00798GentamicinCytoplasmic membranetarget
DB00798GentamicinLow-density lipoprotein receptor-related protein 2transporter
DB00798GentamicinSolute carrier family 22 member 2transporter
DB00798GentamicinCanalicular multispecific organic anion transporter 1transporter
DB09462GlycerinGroup IIE secretory phospholipase A2target
DB09462GlycerinInositol-3-phosphate synthase 1target
DB09462GlycerinAlcohol dehydrogenase 1Btarget
DB09462GlycerinInositol 1,4,5-trisphosphate receptor type 1target
DB09462GlycerinGlycodelintarget
DB09462GlycerinAlpha-N-acetylgalactosaminidasetarget
DB09462GlycerinADP-ribosylation factor 1target
DB09462GlycerinBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1target
DB09462GlycerinDNA mismatch repair protein MutLtarget
DB09462GlycerinRibonucleoside-diphosphate reductase 1 subunit betatarget
DB09462GlycerinA/G-specific adenine glycosylasetarget
DB09462GlycerintRNA (cytosine(38)-C(5))-methyltransferasetarget
DB09462GlycerinCytochrome P450 2E1enzyme
DB09462GlycerinRetinal dehydrogenase 1enzyme
DB09462GlycerinPeroxisome proliferator-activated receptor deltatarget
DB09462GlycerinMaleylacetoacetate isomerasetarget
DB09462GlycerinAquaporin-7transporter
DB09462GlycerinAquaporin-9transporter
DB09462GlycerinGlycerol uptake facilitator proteintransporter
DB11254HexylresorcinolDNA topoisomerase 1target
DB11254HexylresorcinolProtein-glutamine gamma-glutamyltransferase 2target
DB11254HexylresorcinolTyrosinasetarget
DB14539Hydrocortisone acetateAnnexin A1target
DB14539Hydrocortisone acetateGlucocorticoid receptortarget
DB14539Hydrocortisone acetateSex hormone-binding globulincarrier
DB14539Hydrocortisone acetateCytochrome P450 3A4enzyme
DB14539Hydrocortisone acetateCytochrome P450 3A5enzyme
DB14539Hydrocortisone acetateCytochrome P450 3A7enzyme
DB14539Hydrocortisone acetateP-glycoprotein 1transporter
DB14539Hydrocortisone acetateSolute carrier organic anion transporter family member 1A2transporter
DB14539Hydrocortisone acetateATP-binding cassette sub-family G member 2transporter
DB14539Hydrocortisone acetateCytochrome P450 11B1, mitochondrialenzyme
DB14539Hydrocortisone acetateCytochrome P450 11B2, mitochondrialenzyme
DB14539Hydrocortisone acetateCytochrome P450 2C8enzyme
DB14539Hydrocortisone acetateCorticosteroid-binding globulincarrier
DB14539Hydrocortisone acetateCorticosteroid 11-beta-dehydrogenase isozyme 2target
DB14539Hydrocortisone acetate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1target
DB14539Hydrocortisone acetateSolute carrier family 22 member 8transporter
DB14512Mometasone furoateGlucocorticoid receptortarget
DB14512Mometasone furoateCytochrome P450 2C8enzyme
DB14512Mometasone furoateProgesterone receptortarget
DB14512Mometasone furoateCytochrome P450 3A4enzyme
DB14512Mometasone furoateCytochrome P450 3A5enzyme
DB00218MoxifloxacinDNA gyrase subunit Atarget
DB00218MoxifloxacinDNA topoisomerase 4 subunit Atarget
DB00218MoxifloxacinDNA topoisomerase 2-alphatarget
DB00218MoxifloxacinCytochrome P450 1A2enzyme
DB00994Neomycin30S ribosomal protein S12target
DB00994Neomycin16S ribosomal RNAtarget
DB00994NeomycinExtracellular calcium-sensing receptortarget
DB00336NitrofuralGlutathione reductasetarget
DB00336NitrofuralXanthine dehydrogenase/oxidaseenzyme
DB00595Oxytetracycline30S ribosomal protein S4target
DB00595Oxytetracycline30S ribosomal protein S9target
DB00595Oxytetracycline16S ribosomal RNAtarget
DB00595OxytetracyclineSolute carrier family 22 member 6transporter
DB00595OxytetracyclineSolute carrier family 22 member 8transporter
DB00595OxytetracyclineSolute carrier family 22 member 11transporter
DB00595OxytetracyclineSolute carrier family 22 member 7transporter
DB00595OxytetracyclineSerum albumincarrier
DB00778Roxithromycin50S ribosomal protein L10target
DB00778RoxithromycinP-glycoprotein 1target
DB00778RoxithromycinCytochrome P450 3A4enzyme
DB00778RoxithromycinCytochrome P450 2B6enzyme
DB13503TyrothricinAcetylcholinesterasetarget
DB13503TyrothricinBeta-galactosidasetarget
DB13503TyrothricinPhospholipid membranetarget
DrugDrug NamePhaseStatusCount
DB12997Brilacidin2Completed1
DB12347CG-4005492Completed1
DB00080Daptomycin2Completed1
DB11943Delafloxacin2Completed1
DB00254Doxycycline2Recruiting1
DB12587Razupenem2Completed1
DB01015Sulfamethoxazole2Recruiting1
DB00560Tigecycline2Completed1
DB00440Trimethoprim2Recruiting1
DB01597Cilastatin3Completed1
DB00898Ethanol3Unknown Status1
DB01598Imipenem3Completed1
DB00760Meropenem3Completed1
DB00626Bacitracin4Completed1
DB06219Dalbavancin4Recruiting1
DB00080Daptomycin4Completed1
DB14242Honey4Completed1
DB00512Vancomycin4Completed1